PMID- 35681972 OWN - NLM STAT- MEDLINE DCOM- 20220613 LR - 20220716 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 19 IP - 11 DP - 2022 May 24 TI - Risky Sexual Practices, Sexually Transmitted Infections, Motivations, and Mental Health among Heterosexual Women and Men Who Practice Sexualized Drug Use in Spain. LID - 10.3390/ijerph19116387 [doi] LID - 6387 AB - Sexualized drug use (SDU) has been poorly studied among heterosexuals. The purpose of the present study was to analyze the prevalence of and gender differences in types of substances, risky sexual practices, sexually transmitted infections (STIs), motivations, and psychological adjustment among heterosexual women and men who engage in SDU. The study sample consisted of 1181 heterosexuals (795 women) between 18 and 78 years old (mean age = 24.4, SD = 7.4). Approximately 12% of the participants had engaged in SDU. No differences were found in the prevalence of SDU between men and women. Alcohol, cannabis, and 3,4-methylenedioxy-methamphetamine (MDMA) were the substances most frequently used for sexual purposes. Men were significantly more likely to use MDMA, ecstasy, cocaine, and erectile dysfunction (ED) drugs, and they tended to have more sexual partners than women. Likewise, SDU was related to have more sexual partners, penetrative sex without a condom, practice a fetish, be diagnosed with syphilis, chlamydia, and others STIs, and present more depression symptoms (but not with more anxiety). In conclusion, SDU was associated with poorer physical and mental health. It is, therefore, necessary to design programs aimed at reducing the incidence of the consequences of SDU on the physical and mental health of both men and women. Moreover, programs that seek to understand why these individuals engage in SDU should be undertaken. FAU - Incera-Fernandez, Daniel AU - Incera-Fernandez D AD - Department of Personality, Assessment and Psychological Treatment, Autonomous University of Madrid, 28049 Madrid, Spain. FAU - Roman, Francisco J AU - Roman FJ AUID- ORCID: 0000-0003-2342-9531 AD - Department of Personality, Assessment and Psychological Treatment, Autonomous University of Madrid, 28049 Madrid, Spain. FAU - Gamez-Guadix, Manuel AU - Gamez-Guadix M AD - Department of Personality, Assessment and Psychological Treatment, Autonomous University of Madrid, 28049 Madrid, Spain. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20220524 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM MH - Adolescent MH - Adult MH - Aged MH - Cross-Sectional Studies MH - Female MH - *HIV Infections/epidemiology MH - Heterosexuality MH - Homosexuality, Male MH - Humans MH - Male MH - Mental Health MH - Middle Aged MH - Motivation MH - *N-Methyl-3,4-methylenedioxyamphetamine MH - Sexual Behavior MH - Sexual Partners MH - *Sexually Transmitted Diseases/epidemiology MH - Spain/epidemiology MH - *Substance-Related Disorders/epidemiology MH - Young Adult PMC - PMC9180103 OTO - NOTNLM OT - chemsex OT - heterosexual OT - mental health OT - public health OT - sexual behavior OT - sexualized drug use COIS- The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results. EDAT- 2022/06/11 06:00 MHDA- 2022/06/14 06:00 PMCR- 2022/05/24 CRDT- 2022/06/10 01:10 PHST- 2022/03/22 00:00 [received] PHST- 2022/05/18 00:00 [revised] PHST- 2022/05/21 00:00 [accepted] PHST- 2022/06/10 01:10 [entrez] PHST- 2022/06/11 06:00 [pubmed] PHST- 2022/06/14 06:00 [medline] PHST- 2022/05/24 00:00 [pmc-release] AID - ijerph19116387 [pii] AID - ijerph-19-06387 [pii] AID - 10.3390/ijerph19116387 [doi] PST - epublish SO - Int J Environ Res Public Health. 2022 May 24;19(11):6387. doi: 10.3390/ijerph19116387.