PMID- 35685850
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2051-3380 (Print)
IS  - 2051-3380 (Electronic)
IS  - 2051-3380 (Linking)
VI  - 10
IP  - 7
DP  - 2022 Jul
TI  - A case report of coronavirus disease-2019-induced acute asthma exacerbation in an 
      obese patient.
PG  - e0979
LID - 10.1002/rcr2.979 [doi]
LID - e0979
AB  - The coronavirus disease-2019 (COVID-19) has spread worldwide. Previous studies 
      indicated a low prevalence of COVID-19 induced acute exacerbations of asthma. We 
      present a 39-year-old-male obese asthmatic case who experienced acute asthma 
      exacerbation during COVID-19. On day 8 of infection, his cough and dyspnea 
      worsened with hypoxia and wheezing. Laboratory test results revealed elevated 
      interleukin-6 (IL-6) and total immunoglobulin E (IgE) levels without 
      eosinophilia. Two months since the onset, hypoxia disappeared with decreased IL-6 
      and IgE levels. Our case suggested that obesity and high serum IL-6 and IgE 
      levels may have contributed to atypical asthma exacerbation in COVID-19.
CI  - (c) 2022 The Authors. Respirology Case Reports published by John Wiley & Sons 
      Australia, Ltd on behalf of The Asian Pacific Society of Respirology.
FAU - Sasaki, Hisashi
AU  - Sasaki H
AD  - Department of Internal Medicine Japan Self-Defense Forces Central Hospital Tokyo 
      Japan.
AD  - Division of Infectious Diseases and Respiratory Medicine, Department of Internal 
      Medicine National Defense Medical College Saitama Japan.
FAU - Miyata, Jun
AU  - Miyata J
AUID- ORCID: 0000-0002-3189-1702
AD  - Division of Infectious Diseases and Respiratory Medicine, Department of Internal 
      Medicine National Defense Medical College Saitama Japan.
FAU - Kobayashi, Ai
AU  - Kobayashi A
AD  - Department of Internal Medicine Japan Self-Defense Forces Central Hospital Tokyo 
      Japan.
FAU - Kawano, Shuichi
AU  - Kawano S
AD  - Department of Internal Medicine Japan Self-Defense Forces Central Hospital Tokyo 
      Japan.
FAU - Kawana, Akihiko
AU  - Kawana A
AD  - Division of Infectious Diseases and Respiratory Medicine, Department of Internal 
      Medicine National Defense Medical College Saitama Japan.
LA  - eng
PT  - Case Reports
DEP - 20220607
PL  - United States
TA  - Respirol Case Rep
JT  - Respirology case reports
JID - 101631052
PMC - PMC9171688
OTO - NOTNLM
OT  - COVID-19
OT  - asthma
OT  - immunoglobulin E
OT  - interleukin-6
OT  - obesity
COIS- None declared.
EDAT- 2022/06/11 06:00
MHDA- 2022/06/11 06:01
PMCR- 2022/06/07
CRDT- 2022/06/10 02:36
PHST- 2021/12/08 00:00 [received]
PHST- 2022/05/05 00:00 [accepted]
PHST- 2022/06/10 02:36 [entrez]
PHST- 2022/06/11 06:00 [pubmed]
PHST- 2022/06/11 06:01 [medline]
PHST- 2022/06/07 00:00 [pmc-release]
AID - RCR2979 [pii]
AID - 10.1002/rcr2.979 [doi]
PST - epublish
SO  - Respirol Case Rep. 2022 Jun 7;10(7):e0979. doi: 10.1002/rcr2.979. eCollection 
      2022 Jul.