PMID- 35688495
OWN - NLM
STAT- MEDLINE
DCOM- 20220614
LR  - 20220728
IS  - 1873-4111 (Electronic)
IS  - 0378-5122 (Linking)
VI  - 161
DP  - 2022 Jul
TI  - Longitudinal trajectories of intrinsic capacity and their association with 
      quality of life and disability.
PG  - 49-54
LID - S0378-5122(22)00047-0 [pii]
LID - 10.1016/j.maturitas.2022.02.005 [doi]
AB  - OBJECTIVES: Intrinsic capacity (IC) is a key concept within the World Health 
      Organization's (WHO) healthy aging model. The systematic assessment of IC could 
      provide a better understanding of the functional trajectories of individuals. Our 
      aims were to identify the longitudinal trajectories of IC and estimate their 
      association with quality of life and disability. STUDY DESIGN: The study data 
      comes from the three waves of the WHO Study on global AGEing and adult health 
      (SAGE) in Mexico (2009, 2014, 2017). In total, 2735 adults aged 50 years or more 
      were included. An IC score was constructed using item response theory. We used 
      growth mixture modeling (GMM) to investigate the longitudinal trajectories of IC. 
      Three-level linear mixed effect models were used to estimate the associations of 
      IC with quality of life and disability. MAIN OUTCOME MEASURES: Disability was 
      measured using the WHO Disability Assessment Schedule (WHODAS 2.0) and quality of 
      life using the WHOQOL (WHO Quality of Life) instrument. RESULTS: Three classes 
      were identified: low baseline IC with a steeply decreasing trajectory, medium 
      baseline IC with a slightly decreasing trajectory, and high baseline IC with a 
      moderately increasing trajectory. The class with the better trajectory (higher 
      baseline IC score and a moderately increasing pattern) exhibited higher 
      quality-of-life scores and lower disability scores. CONCLUSIONS: The findings 
      show that older Mexican adults exhibit different IC trajectories, and that these 
      may be associated with quality of life and disability. Results highlight the need 
      for health policies and strategies to maintain intrinsic capacity and to promote 
      primary prevention.
CI  - Copyright (c) 2022 Elsevier B.V. All rights reserved.
FAU - Salinas-Rodriguez, Aaron
AU  - Salinas-Rodriguez A
AD  - Center for Evaluation and Surveys Research, National Institute of Public Health, 
      Av. Universidad #655. Colonia Santa Maria Ahuacatitlan, Cuernavaca, Morelos ZC 
      62100, Mexico.
FAU - Gonzalez-Bautista, Emmanuel
AU  - Gonzalez-Bautista E
AD  - Gerontopole of Toulouse, Institute of Aging, Toulouse University Hospital (CHU 
      Toulouse). CERPOP, Universite de Toulouse, Inserm, UPS, Toulouse, France.
FAU - Rivera-Almaraz, Ana
AU  - Rivera-Almaraz A
AD  - Center for Evaluation and Surveys Research, National Institute of Public Health, 
      Av. Universidad #655. Colonia Santa Maria Ahuacatitlan, Cuernavaca, Morelos ZC 
      62100, Mexico.
FAU - Manrique-Espinoza, Betty
AU  - Manrique-Espinoza B
AD  - Center for Evaluation and Surveys Research, National Institute of Public Health, 
      Av. Universidad #655. Colonia Santa Maria Ahuacatitlan, Cuernavaca, Morelos ZC 
      62100, Mexico. Electronic address: bmanrique@insp.mx.
LA  - eng
PT  - Journal Article
DEP - 20220226
PL  - Ireland
TA  - Maturitas
JT  - Maturitas
JID - 7807333
SB  - IM
MH  - Aging/physiology
MH  - *Disabled Persons
MH  - Humans
MH  - Longitudinal Studies
MH  - Mexico
MH  - *Quality of Life
OTO - NOTNLM
OT  - Disability
OT  - Growth mixture modeling
OT  - Intrinsic capacity
OT  - Longitudinal trajectories
OT  - Quality of life
COIS- The authors declare that they have no competing interests.
EDAT- 2022/06/11 06:00
MHDA- 2022/06/15 06:00
CRDT- 2022/06/10 21:04
PHST- 2021/06/10 00:00 [received]
PHST- 2022/02/01 00:00 [revised]
PHST- 2022/02/18 00:00 [accepted]
PHST- 2022/06/10 21:04 [entrez]
PHST- 2022/06/11 06:00 [pubmed]
PHST- 2022/06/15 06:00 [medline]
AID - S0378-5122(22)00047-0 [pii]
AID - 10.1016/j.maturitas.2022.02.005 [doi]
PST - ppublish
SO  - Maturitas. 2022 Jul;161:49-54. doi: 10.1016/j.maturitas.2022.02.005. Epub 2022 
      Feb 26.