PMID- 35709212
OWN - NLM
STAT- MEDLINE
DCOM- 20220620
LR  - 20220718
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 17
IP  - 6
DP  - 2022
TI  - The correlation between serum albumin and diabetic retinopathy among people with 
      type 2 diabetes mellitus: NHANES 2011-2020.
PG  - e0270019
LID - 10.1371/journal.pone.0270019 [doi]
LID - e0270019
AB  - OBJECTIVES: The objective of this research aimed to investigate the correlation 
      involving serum albumin with diabetic retinopathy (DR) in patients with type 2 
      diabetes mellitus (T2DM). METHODS: From 2011 to 2020, the National Health and 
      Nutrition Examination Survey (NHANES) surveyed 45462 participants. We used the 
      relevant data to conduct descriptive statistics, linear regression, and Logistic 
      regression analysis. RESULTS: After adjusting for age, sex, and race, as well as 
      all other variables, serum albumin was significantly negatively related to DR 
      (P<0.001). Furthermore, after controlling for confounding factors, the third 
      quartile (Q3) and the fourth quartile (Q4) had quite a negative significant 
      relationship with the incidence of DR (P<0.01). The second quartile had a 
      significant positive correlation with DR, whereas the observed negative 
      correlations were not statistically meaningful (P>0.05). CONCLUSION: Albumin 
      levels in the serum have a quantitatively significant negative correlation with 
      DR. Serum albumin levels in the blood can be used as a reference point for 
      protracted follow-up of people with T2DM.
FAU - Wang, Gao-Xiang
AU  - Wang GX
AD  - Shenzhen Traditional Chinese Medicine Hospital Affiliated to Nanjing University 
      of Chinese Medicine, Shenzhen, Guangdong, China.
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, Guangdong, China.
FAU - Fang, Ze-Bin
AU  - Fang ZB
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, Guangdong, China.
AD  - The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, 
      Shenzhen, Guangdong, China.
FAU - Li, Jun-Tong
AU  - Li JT
AD  - Shenzhen Traditional Chinese Medicine Hospital Affiliated to Nanjing University 
      of Chinese Medicine, Shenzhen, Guangdong, China.
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, Guangdong, China.
FAU - Huang, Bao-Li
AU  - Huang BL
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, Guangdong, China.
AD  - The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, 
      Shenzhen, Guangdong, China.
FAU - Liu, De-Liang
AU  - Liu DL
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, Guangdong, China.
FAU - Chu, Shu-Fang
AU  - Chu SF
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, Guangdong, China.
FAU - Li, Hui-Lin
AU  - Li HL
AUID- ORCID: 0000-0002-4888-1025
AD  - Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, 
      Shenzhen, Guangdong, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220616
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
RN  - 0 (Serum Albumin)
SB  - IM
MH  - *Diabetes Mellitus, Type 2
MH  - *Diabetic Retinopathy/diagnosis
MH  - Humans
MH  - Nutrition Surveys
MH  - Risk Factors
MH  - Serum Albumin
PMC - PMC9202838
COIS- NO authors have competing interests.
EDAT- 2022/06/17 06:00
MHDA- 2022/06/22 06:00
PMCR- 2022/06/16
CRDT- 2022/06/16 13:54
PHST- 2022/04/18 00:00 [received]
PHST- 2022/06/02 00:00 [accepted]
PHST- 2022/06/16 13:54 [entrez]
PHST- 2022/06/17 06:00 [pubmed]
PHST- 2022/06/22 06:00 [medline]
PHST- 2022/06/16 00:00 [pmc-release]
AID - PONE-D-22-11341 [pii]
AID - 10.1371/journal.pone.0270019 [doi]
PST - epublish
SO  - PLoS One. 2022 Jun 16;17(6):e0270019. doi: 10.1371/journal.pone.0270019. 
      eCollection 2022.