PMID- 35718568
OWN - NLM
STAT- MEDLINE
DCOM- 20220907
LR  - 20220907
IS  - 1773-0597 (Electronic)
IS  - 0181-5512 (Linking)
VI  - 45
IP  - 7
DP  - 2022 Sep
TI  - Filler-induced blindness "seen" by ophthalmologists: Case presentation and 
      treatment algorithm.
PG  - 771-783
LID - S0181-5512(22)00234-0 [pii]
LID - 10.1016/j.jfo.2022.03.005 [doi]
AB  - PURPOSE: Filler-induced blindness (FIB) is the most threatening complication 
      following periocular injection. To date, no standard of care has been 
      established. The goal of this study is to report a new case of FIB with partial 
      visual recovery and present our personalized algorithm for treatment based on 
      fluorescein angiography findings. MATERIALS AND METHODS: Case report with 24 
      months follow-up and treatment algorithm. RESULTS: Our patient experienced 
      complete vision loss to no light perception following forehead lipofilling. 
      Retinal angiography identified a posterior ciliary artery occlusion. Antiplatelet 
      medication, steroids and intraocular pressure lowering medications were 
      administrated, followed by hyperbaric oxygen treatment (HBOT). Visual acuity 
      improved to +0.8 logMar. The HBOT treatment was monitored by fluorescein 
      angiogram. Based on this case and on the ophthalmic literature on retinal and 
      ciliary artery occlusion, we established a personalized FIB protocol guided by 
      fluorescein angiography. CONCLUSION: Although prevention remains the best 
      treatment, all physicians should be prepared to manage FIB. Prompt management at 
      the office guided by written protocols, as well as emergency kits, are essential. 
      In referral centers, personalized treatment should be undertaken based on 
      fluorescein angiography findings.
CI  - Copyright (c) 2022 Elsevier Masson SAS. All rights reserved.
FAU - Martel, A
AU  - Martel A
AD  - Ophthalmology department, University Hospital of Nice, Cote d'Azur University, 
      30, voie romaine, 06000 Nice, France. Electronic address: 
      arnaudmartel@hotmail.fr.
FAU - Lagier, J
AU  - Lagier J
AD  - Ophthalmology department, University Hospital of Nice, Cote d'Azur University, 
      30, voie romaine, 06000 Nice, France.
FAU - Sarfati, E
AU  - Sarfati E
AD  - Ophthalmology department, Toulon Hospital, Toulon, France.
FAU - Malet, T
AU  - Malet T
AD  - Monticelli eye centre, Marseille, France.
FAU - Rocher, F
AU  - Rocher F
AD  - Pharmacovigilance department, University Hospital of Nice, 30, voie romaine, 
      06000 Nice, France.
FAU - Kauert, A
AU  - Kauert A
AD  - Hyperbaric oxygen department, University Hospital of Nice, 30, voie romaine, 
      06000 Nice, France.
FAU - Baillif, S
AU  - Baillif S
AD  - Ophthalmology department, University Hospital of Nice, Cote d'Azur University, 
      30, voie romaine, 06000 Nice, France.
FAU - Chignon-Sicard, B
AU  - Chignon-Sicard B
AD  - Plastic and reconstructive department, University Hospital of Nice, Cote d'Azur 
      University, 30, voie romaine, 06000 Nice, France.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20220616
PL  - France
TA  - J Fr Ophtalmol
JT  - Journal francais d'ophtalmologie
JID - 7804128
SB  - IM
MH  - Algorithms
MH  - Blindness/chemically induced/diagnosis
MH  - Fluorescein Angiography
MH  - Humans
MH  - *Ophthalmologists
MH  - *Retinal Artery Occlusion/etiology
OTO - NOTNLM
OT  - Acide hyaluronique
OT  - Angiographie
OT  - Angiography
OT  - Blindness
OT  - Cecite
OT  - Filler
OT  - Hyaluronic acid
OT  - Hyperbaric oxygen
OT  - Injection peribulbaire
OT  - Oxygene hyperbare
OT  - Peribulbar injection
EDAT- 2022/06/20 06:00
MHDA- 2022/09/08 06:00
CRDT- 2022/06/19 22:14
PHST- 2022/02/07 00:00 [received]
PHST- 2022/03/13 00:00 [accepted]
PHST- 2022/06/20 06:00 [pubmed]
PHST- 2022/09/08 06:00 [medline]
PHST- 2022/06/19 22:14 [entrez]
AID - S0181-5512(22)00234-0 [pii]
AID - 10.1016/j.jfo.2022.03.005 [doi]
PST - ppublish
SO  - J Fr Ophtalmol. 2022 Sep;45(7):771-783. doi: 10.1016/j.jfo.2022.03.005. Epub 2022 
      Jun 16.