PMID- 35718694 OWN - NLM STAT- MEDLINE DCOM- 20231023 LR - 20231025 IS - 1878-0938 (Electronic) IS - 1553-8389 (Print) IS - 1878-0938 (Linking) VI - 53S DP - 2023 Aug TI - A Case of ST Segment Elevation Myocardial Infarction Within 24 h of a Third Dose of COVID-19 mRNA Vaccine. PG - S313-S316 LID - S1553-8389(22)00304-9 [pii] LID - 10.1016/j.carrev.2022.06.012 [doi] AB - Although coronavirus disease 2019 (COVID-19) vaccination is known to carry a slight risk of myocarditis and pericarditis, it remains unclear whether it has any impact on coronary artery disease. Here we present a case without particular thrombotic diathesis with a diagnosis of ST segment elevation acute myocardial infarction (STEMI) 19 h after a third dose of a COVID-19 mRNA vaccine. A primary percutaneous coronary intervention procedure for occluded right coronary artery with thrombus aspiration alone was successful in this patient. However, the relationship between STEMI and COVID-19 mRNA vaccination is uncertain, and additional studies to validate thrombogenetic effects of COVID-19 mRNA vaccines are needed. This case was helpful in distinguishing STEMI from myocarditis and pericarditis, which are recognized rare cardiac side effects of COVID-19 vaccination. It is important not to hesitate to perform coronary angiography procedures to rule out the possibility of STEMI occurrence, as in this case. CI - Copyright (c) 2022 Elsevier Inc. All rights reserved. FAU - Kawamura, Yota AU - Kawamura Y AD - Tokai University Hachioji Hospital, Division of Cardiology, Department of Internal Medicine, Hachioji, Japan. Electronic address: youta@f4.dion.ne.jp. FAU - Yoshimachi, Fuminobu AU - Yoshimachi F AD - Tokai University Hachioji Hospital, Division of Cardiology, Department of Internal Medicine, Hachioji, Japan. FAU - Nanao, Tomihisa AU - Nanao T AD - Tokai University Hachioji Hospital, Division of Cardiology, Department of Internal Medicine, Hachioji, Japan. FAU - Kasai, Satoshi AU - Kasai S AD - Tokai University Hachioji Hospital, Division of Cardiology, Department of Internal Medicine, Hachioji, Japan. FAU - Ikari, Yuji AU - Ikari Y AD - Tokai University School of Medicine, Division of Cardiology, Department of Internal Medicine, Isehara, Japan. LA - eng PT - Case Reports DEP - 20220615 PL - United States TA - Cardiovasc Revasc Med JT - Cardiovascular revascularization medicine : including molecular interventions JID - 101238551 RN - 0 (COVID-19 Vaccines) RN - 0 (mRNA Vaccines) SB - IM MH - Humans MH - Coronary Angiography MH - *COVID-19/complications MH - *COVID-19 Vaccines/adverse effects MH - mRNA Vaccines MH - *Myocarditis MH - *Percutaneous Coronary Intervention/methods MH - *Pericarditis MH - *ST Elevation Myocardial Infarction/diagnostic imaging/therapy MH - *Thrombosis MH - Treatment Outcome PMC - PMC9197822 OTO - NOTNLM OT - Acute myocardial infarction OT - COVID-19 OT - Vaccine COIS- Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2022/06/20 06:00 MHDA- 2023/10/23 12:43 PMCR- 2022/06/15 CRDT- 2022/06/19 22:18 PHST- 2022/05/04 00:00 [received] PHST- 2022/06/08 00:00 [revised] PHST- 2022/06/10 00:00 [accepted] PHST- 2023/10/23 12:43 [medline] PHST- 2022/06/20 06:00 [pubmed] PHST- 2022/06/19 22:18 [entrez] PHST- 2022/06/15 00:00 [pmc-release] AID - S1553-8389(22)00304-9 [pii] AID - 10.1016/j.carrev.2022.06.012 [doi] PST - ppublish SO - Cardiovasc Revasc Med. 2023 Aug;53S:S313-S316. doi: 10.1016/j.carrev.2022.06.012. Epub 2022 Jun 15.