PMID- 35719246
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 1178-7007 (Print)
IS  - 1178-7007 (Electronic)
IS  - 1178-7007 (Linking)
VI  - 15
DP  - 2022
TI  - Association Between Some Different Obesity Anthropometric Indices and Type 2 
      Diabetes Mellitus in Middle-Aged and Elderly Chinese Men and Women in Beijing, 
      China: A Cross-Sectional Study.
PG  - 1799-1807
LID - 10.2147/DMSO.S359657 [doi]
AB  - BACKGROUND: Obesity can lead to the development of type 2 diabetes mellitus 
      (T2DM). However, the predictive power of different obesity anthropometric indices 
      (ObAIs) for T2DM varies with race and geographical area. Therefore, the study 
      aimed to investigate the association between different ObAIs and T2DM and 
      determine the best index for screening T2DM in middle-aged and elderly men and 
      women in Beijing, China. METHODS: A cross-sectional study was conducted in 
      Shijingshan district (Beijing, China) from November 2011 to August 2012, 
      involving a total of 14,558 subjects aged >/=40 years. Data on demographic 
      information, lifestyle, history of T2DM, hypertension and dyslipidemia were 
      collected. Body height, body weight, waist circumference (WC), hip circumference, 
      and blood pressure were recorded. The oral glucose tolerance test or a standard 
      meal test and blood lipid test were performed. The relationship between different 
      ObAIs and T2DM was analyzed using multiple logistic regression. RESULTS: After 
      adjustment for age, smoking status, alcohol intake, occupation and education 
      degree, diabetes family history, hypertension and dyslipidemia, body mass index 
      (BMI), WC, waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) were 
      positively associated with T2DM in both men and women. Compared with the lowest 
      BMI, WC, WHR, and WHtR quartiles, ORs of the highest quartiles were 2.131 (95% 
      CI: 1.465-3.099), 1.752 (95% CI: 1.270-2.417), 1.342 (95% CI: 1.072-1.678), 2.739 
      (95% CI: 2.293-3.271) in men and 1.837 (95% CI: 1.584-2.130), 3.122 (95% CI: 
      1.980-4.924), 3.781 (95% CI: 2.855-5.007), 2.379 (85% CI: 2.040-2.775), 
      respectively, in women. The areas under ROC curve of BMI, WC, WHR, and WHtR for 
      men were 0.584 (95% CI: 0.568-0.600), 0.509 (95% CI: 0.492-0.525), 0.501 (95% CI: 
      0.485-0.518), and 0.642 (95% CI: 0.627-0.658) and 0.619 (95% CI: 0.607-0.632), 
      0.709 (95% CI: 0.697-0.720), 0.741 (95% CI: 0.730-0.752), and 0.654 (95% CI: 
      0.642-0.666), respectively, for women. CONCLUSION: WHtR and WHR have been found 
      to perform better as predictors of T2DM in middle-aged and elderly Chinese men 
      and women, respectively.
CI  - (c) 2022 Zhang et al.
FAU - Zhang, Xuebing
AU  - Zhang X
AD  - Department of Endocrinology, Dongzhimen Hospital Beijing University of Chinese 
      Medicine, Beijing, 100700, People's Republic of China.
FAU - Yan, Wenhua
AU  - Yan W
AD  - Department of Endocrinology, First Medical Centre of Chinese PLA General 
      Hospital, Beijing, 100853, People's Republic of China.
FAU - Wang, Bing
AU  - Wang B
AD  - Department of Endocrinology, Emergency General Hospital, Beijing, 100028, 
      People's Republic of China.
FAU - Wang, Lianjie
AU  - Wang L
AD  - Department of Endocrinology, Dongzhimen Hospital Beijing University of Chinese 
      Medicine, Beijing, 100700, People's Republic of China.
FAU - Mu, Yiming
AU  - Mu Y
AUID- ORCID: 0000-0002-3344-3540
AD  - Department of Endocrinology, First Medical Centre of Chinese PLA General 
      Hospital, Beijing, 100853, People's Republic of China.
FAU - Wang, Shidong
AU  - Wang S
AD  - Department of Endocrinology, Dongzhimen Hospital Beijing University of Chinese 
      Medicine, Beijing, 100700, People's Republic of China.
LA  - eng
PT  - Journal Article
DEP - 20220611
PL  - New Zealand
TA  - Diabetes Metab Syndr Obes
JT  - Diabetes, metabolic syndrome and obesity : targets and therapy
JID - 101515585
PMC - PMC9199527
OTO - NOTNLM
OT  - Chinese
OT  - anthropometric indices
OT  - middle-aged and elderly
OT  - obesity
OT  - type 2 diabetes mellitus
COIS- The authors declare no conflicts of interest in this work.
EDAT- 2022/06/21 06:00
MHDA- 2022/06/21 06:01
PMCR- 2022/06/11
CRDT- 2022/06/20 03:27
PHST- 2022/01/23 00:00 [received]
PHST- 2022/05/10 00:00 [accepted]
PHST- 2022/06/20 03:27 [entrez]
PHST- 2022/06/21 06:00 [pubmed]
PHST- 2022/06/21 06:01 [medline]
PHST- 2022/06/11 00:00 [pmc-release]
AID - 359657 [pii]
AID - 10.2147/DMSO.S359657 [doi]
PST - epublish
SO  - Diabetes Metab Syndr Obes. 2022 Jun 11;15:1799-1807. doi: 10.2147/DMSO.S359657. 
      eCollection 2022.