PMID- 35720241 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220716 IS - 2668-0572 (Electronic) IS - 2602-0807 (Print) IS - 2602-0807 (Linking) VI - 95 IP - 1 DP - 2022 Jan TI - Effect of micro osteo-perforations (MOP) on the rate of tooth movement and levels of interleukin- 1beta - a split mouth study. PG - 65-70 LID - 10.15386/mpr-1911 [doi] AB - INTRODUCTION: Various procedures are available today to enhance tooth movement, with relative success rates, one among them being micro osteo-perforation (MOP). Our aim is to assess the rate of tooth movement and interleukin-1beta levels in gingival crevicular fluid levels (GCF) after MOPs. METHODS: A group of 22 patients were selected, who required first premolars extraction and were designated for the split mouth study with equal allocation. MOP was performed on the right side, three vertical MOPs were given using 1.2 X 8 mm mini implants with the gap of 2 mm between them and surgical depth of the implant insertion was 5 mm. The left side was used as control. The individual canine retraction was initiated with placement of 150 grams on 19*25 SS wire. The case was evaluated at different timelines for canine retraction and interleukin-1beta levels. RESULTS: There was a significant difference in the rate of canine movement at 45 days (1.42 mm) and end of canine retraction on experimental side (2.61 mm). The GCF levels were raised at T1 and T2 intervals on the side of MOP and were statically significant (p=0.00). CONCLUSION: MOP is a minimally invasive procedure which accelerates the tooth movement by 20%. The increase in IL-1beta levels indicates a higher rate of chemical interaction on the surgically assisted side. For enhanced efficiency MOPs should be repeated every 6-8 weeks. FAU - Bavikati, Venkata Naidu AU - Bavikati VN AD - Department of Orthodontics, AME's Dental College & Hospital, Raichur, Karnataka, India. FAU - Muhameed, Abdul Rasheed AU - Muhameed AR AD - Department of Orthodontics, AME's Dental College & Hospital, Raichur, Karnataka, India. FAU - Mohaley, Nikitha AU - Mohaley N AD - Department of Orthodontics, AME's Dental College & Hospital, Raichur, Karnataka, India. FAU - Thimmaiah, Manjula K AU - Thimmaiah MK AD - Department of Orthodontics, AME's Dental College & Hospital, Raichur, Karnataka, India. FAU - Botlagunta, Keerthi Kavya AU - Botlagunta KK AD - Department of Orthodontics, AME's Dental College & Hospital, Raichur, Karnataka, India. FAU - Basalingappa, Sangamesh AU - Basalingappa S AD - Department of Orthodontics, AME's Dental College & Hospital, Raichur, Karnataka, India. LA - eng PT - Journal Article DEP - 20220131 PL - Romania TA - Med Pharm Rep JT - Medicine and pharmacy reports JID - 101742144 PMC - PMC9177089 OTO - NOTNLM OT - MOP OT - interleukin-1beta OT - micro osteo-perforations OT - rapid tooth movement OT - tooth movement EDAT- 2022/06/21 06:00 MHDA- 2022/06/21 06:01 PMCR- 2022/01/01 CRDT- 2022/06/20 03:39 PHST- 2020/09/23 00:00 [received] PHST- 2021/01/12 00:00 [revised] PHST- 2021/01/24 00:00 [accepted] PHST- 2022/06/20 03:39 [entrez] PHST- 2022/06/21 06:00 [pubmed] PHST- 2022/06/21 06:01 [medline] PHST- 2022/01/01 00:00 [pmc-release] AID - cm-95-65 [pii] AID - 10.15386/mpr-1911 [doi] PST - ppublish SO - Med Pharm Rep. 2022 Jan;95(1):65-70. doi: 10.15386/mpr-1911. Epub 2022 Jan 31.