PMID- 35726733
OWN - NLM
STAT- MEDLINE
DCOM- 20230302
LR  - 20230302
IS  - 1940-1574 (Electronic)
IS  - 0003-3197 (Linking)
VI  - 74
IP  - 4
DP  - 2023 Apr
TI  - The Association of Serum Uric Acid/Albumin Ratio with No-Reflow in Patients with 
      ST Elevation Myocardial Infarction.
PG  - 381-386
LID - 10.1177/00033197221110700 [doi]
AB  - The goal of this investigation was to explore the relationship between serum uric 
      acid/albumin ratio (UAR) and no-reflow (NR) in ST elevation myocardial infarction 
      (STEMI) patients (n = 838) who underwent primary percutaneous coronary 
      intervention (pPCI). Angiographic NR was defined as thrombolysis in myocardial 
      infarction (TIMI) flows 0, 1, and 2 in the absence of coronary spasm or 
      dissection. NR developed in 91 (10.9%) STEMI patients. Patients with NR had 
      higher UAR and according to multivariable logistic regression models, a high UAR 
      was an independent risk factor for NR. The area under the curve (AUC) value of 
      the UAR was .760 (95%CI: .720-.801) in a receiver-operating characteristics curve 
      (ROC) assessment. Notably, the UAR AUC value was greater than that of its 
      components: albumin (AUC: .642) and serum uric acid (AUC: .637) (P < .05 for both 
      comparisons). The optimum UAR value in detecting NR in STEMI patients was >1.21 
      with a sensitivity of 82% and a specificity of 67%. This was the first study to 
      report that the UAR was independently associated with NR in STEMI patients who 
      underwent pPCI.
FAU - Cinar, Tufan
AU  - Cinar T
AUID- ORCID: 0000-0001-8188-5020
AD  - Department of Cardiology, 506079Istanbul Sultan II Abdulhamid Han Training and 
      Research Hospital, Istanbul, Turkey.
FAU - Saylik, Faysal
AU  - Saylik F
AUID- ORCID: 0000-0003-3165-6769
AD  - Department of Cardiology, 64259Van Training and Research Hospital, Van, Turkey.
FAU - Hayiroglu, Mert Ilker
AU  - Hayiroglu MI
AUID- ORCID: 0000-0001-6515-7349
AD  - Department of Cardiology, 111319Siyami Ersek Training and Research Hospital, 
      Istanbul, Turkey.
FAU - Asal, Suha
AU  - Asal S
AD  - Department of Cardiology, 506079Istanbul Sultan II Abdulhamid Han Training and 
      Research Hospital, Istanbul, Turkey.
FAU - Selcuk, Murat
AU  - Selcuk M
AD  - Department of Cardiology, 506079Istanbul Sultan II Abdulhamid Han Training and 
      Research Hospital, Istanbul, Turkey.
FAU - Cicek, Vedat
AU  - Cicek V
AD  - Department of Cardiology, 506079Istanbul Sultan II Abdulhamid Han Training and 
      Research Hospital, Istanbul, Turkey.
FAU - Tanboga, Ibrahim Halil
AU  - Tanboga IH
AD  - Department of Cardiology, Hisar Intercontinental Hospital, Istanbul, Turkey.
AD  - Department of Cardiology, 385796Nisantasi University, Istanbul, Turkey.
AD  - Department of Biostatistics, Ataturk University, Erzurum, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20220621
PL  - United States
TA  - Angiology
JT  - Angiology
JID - 0203706
RN  - 268B43MJ25 (Uric Acid)
RN  - 0 (Albumins)
SB  - IM
MH  - Humans
MH  - *ST Elevation Myocardial Infarction/diagnostic imaging/therapy
MH  - Uric Acid
MH  - Prognosis
MH  - Coronary Angiography
MH  - *Percutaneous Coronary Intervention
MH  - Albumins
MH  - *No-Reflow Phenomenon/etiology
OTO - NOTNLM
OT  - ST elevation myocardial infarction
OT  - no-reflow
OT  - primary percutaneous coronary intervention
OT  - uric acid/albumin ratio
EDAT- 2022/06/22 06:00
MHDA- 2023/03/03 06:00
CRDT- 2022/06/21 06:12
PHST- 2022/06/22 06:00 [pubmed]
PHST- 2023/03/03 06:00 [medline]
PHST- 2022/06/21 06:12 [entrez]
AID - 10.1177/00033197221110700 [doi]
PST - ppublish
SO  - Angiology. 2023 Apr;74(4):381-386. doi: 10.1177/00033197221110700. Epub 2022 Jun 
      21.