PMID- 35741232 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220716 IS - 2075-4418 (Print) IS - 2075-4418 (Electronic) IS - 2075-4418 (Linking) VI - 12 IP - 6 DP - 2022 Jun 9 TI - Diagnosis of Tooth Prognosis Using Artificial Intelligence. LID - 10.3390/diagnostics12061422 [doi] LID - 1422 AB - The accurate diagnosis of individual tooth prognosis has to be determined comprehensively in consideration of the broader treatment plan. The objective of this study was to establish an effective artificial intelligence (AI)-based module for an accurate tooth prognosis decision based on the Harvard School of Dental Medicine (HSDM) comprehensive treatment planning curriculum (CTPC). The tooth prognosis of 2359 teeth from 94 cases was evaluated with 1 to 5 levels (1-Hopeless, 5-Good condition for long term) by two groups (Model-A with 16, and Model-B with 13 examiners) based on 17 clinical determining factors selected from the HSDM-CTPC. Three AI machine-learning methods including gradient boosting classifier, decision tree classifier, and random forest classifier were used to create an algorithm. These three methods were evaluated against the gold standard data determined by consensus of three experienced prosthodontists, and their accuracy was analyzed. The decision tree classifier indicated the highest accuracy at 0.8413 (Model-A) and 0.7523 (Model-B). Accuracy with the gradient boosting classifier and the random forest classifier was 0.6896, 0.6687, and 0.8413, 0.7523, respectively. Overall, the decision tree classifier had the best accuracy among the three methods. The study contributes to the implementation of AI in the decision-making process of tooth prognosis in consideration of the treatment plan. FAU - Lee, Sang J AU - Lee SJ AUID- ORCID: 0000-0001-7142-2890 AD - Department of Restorative Dentistry and Biomaterial Sciences, Harvard School of Dental Medicine, Boston, MA 02115, USA. FAU - Chung, Dahee AU - Chung D AD - Harvard School of Dental Medicine, Boston, MA 02115, USA. FAU - Asano, Akiko AU - Asano A AD - Department of Restorative Dentistry, School of Dental Medicine, Iwate Medical University, Morioka 020-8505, Japan. FAU - Sasaki, Daisuke AU - Sasaki D AD - Department of Periodontology, School of Dental Medicine, Iwate Medical University, Morioka 020-8505, Japan. FAU - Maeno, Masahiko AU - Maeno M AD - Department of Adhesive Dentistry, School of Life Dentistry at Tokyo, The Nippon Dental University, Chiyoda-ku, Tokyo 102-8159, Japan. FAU - Ishida, Yoshiki AU - Ishida Y AUID- ORCID: 0000-0002-8686-3215 AD - Department of Dental Materials Science, School of Life Dentistry at Tokyo, The Nippon Dental University, Chiyoda-ku, Tokyo 102-8159, Japan. FAU - Kobayashi, Takuya AU - Kobayashi T AD - Department of Oral Rehabilitation, School of Dental Medicine, Iwate Medical University, Morioka 020-8505, Japan. FAU - Kuwajima, Yukinori AU - Kuwajima Y AD - Department of Orthodontics, School of Dental Medicine, Iwate Medical University, Morioka 020-8505, Japan. FAU - Da Silva, John D AU - Da Silva JD AUID- ORCID: 0000-0002-3341-6681 AD - Department of Restorative Dentistry and Biomaterial Sciences, Harvard School of Dental Medicine, Boston, MA 02115, USA. FAU - Nagai, Shigemi AU - Nagai S AD - Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA 02115, USA. LA - eng PT - Journal Article DEP - 20220609 PL - Switzerland TA - Diagnostics (Basel) JT - Diagnostics (Basel, Switzerland) JID - 101658402 PMC - PMC9221626 OTO - NOTNLM OT - artificial intelligence (AI) OT - diagnosis OT - machine learning OT - prosthodontics OT - tooth prognosis OT - treatment plan COIS- The authors declare no conflict of interest. EDAT- 2022/06/25 06:00 MHDA- 2022/06/25 06:01 PMCR- 2022/06/09 CRDT- 2022/06/24 01:10 PHST- 2022/05/24 00:00 [received] PHST- 2022/06/06 00:00 [revised] PHST- 2022/06/07 00:00 [accepted] PHST- 2022/06/24 01:10 [entrez] PHST- 2022/06/25 06:00 [pubmed] PHST- 2022/06/25 06:01 [medline] PHST- 2022/06/09 00:00 [pmc-release] AID - diagnostics12061422 [pii] AID - diagnostics-12-01422 [pii] AID - 10.3390/diagnostics12061422 [doi] PST - epublish SO - Diagnostics (Basel). 2022 Jun 9;12(6):1422. doi: 10.3390/diagnostics12061422.