PMID- 35747852
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 1841-0987 (Print)
IS  - 1843-066X (Electronic)
IS  - 1841-0987 (Linking)
VI  - 17
IP  - 4
DP  - 2021 Oct-Dec
TI  - Platelet indices in patients with type 2 diabetes mellitus undergoing 
      percutaneous coronary intervention.
PG  - 543-547
LID - 10.4183/aeb.2021.543 [doi]
AB  - CONTEXT: Platelet indices change in relation to cardiovascular risk factors, 
      including type 2 diabetes mellitus (T2DM). An increase of platelet indices over 
      time in patients undergoing percutaneous coronary intervention (PCI) could be a 
      predictor of mortality.The objective of this study was to assess differences in 
      platelet indices in patients with and without T2DM undergoing PCI, prior and more 
      than one month after the procedure. SUBJECTS AND METHODS: In this retrospective 
      observational study, patients undergoing PCI were included. Data were extracted 
      from PCI Registry of the Emergency Institute for Cardiovascular Diseases and 
      Transplantation of Tirgu Mures, Romania. RESULTS: Of the 718 patients included in 
      the study, 222 (30.9%) had T2DM; 61% of patient underwent PCI for SCAD, the rest 
      for NSTE-ACS or STEMI. Prior to PCI, MPV, PDW and P-LCR were not higher in T2DM 
      patients irrespective of the indication for PCI. At a follow-up time of 69 
      (46-98) days, platelet indices were not different between TD2M+ and T2DM-, except 
      from MPV (11.0 vs. 10.6, p=0.02) which were higher in TD2M patients with SCAD. 
      Intraindividual variability of platelet indices was not different in diabetics, 
      but MPV, PDW and platelet count decreased over time (3.5% and 8.4% respectively) 
      in diabetics with STEMI (p=0.02). CONCLUSIONS: Platelet indices were not higher 
      in patients with T2DM undergoing PCI, but we observed an important variation in 
      platelet indices in diabetics after STEMI related PCI.
CI  - (c)2021 Acta Endocrinologica (Buc).
FAU - Sus, I
AU  - Sus I
AD  - "George Emil Palade" University of Medicine, Pharmacy, Science and Technology, 
      Tirgu Mures, Romania.
AD  - Emergency Institute for Cardiovascular Diseases and Transplantation - Tirgu 
      Mures, Romania.
FAU - Hadadi, L
AU  - Hadadi L
AD  - "George Emil Palade" University of Medicine, Pharmacy, Science and Technology, 
      Tirgu Mures, Romania.
AD  - Emergency Institute for Cardiovascular Diseases and Transplantation - Tirgu 
      Mures, Romania.
FAU - Somkereki, C
AU  - Somkereki C
AD  - "George Emil Palade" University of Medicine, Pharmacy, Science and Technology, 
      Tirgu Mures, Romania.
AD  - Emergency Institute for Cardiovascular Diseases and Transplantation - Tirgu 
      Mures, Romania.
FAU - Dobreanu, D
AU  - Dobreanu D
AD  - "George Emil Palade" University of Medicine, Pharmacy, Science and Technology, 
      Tirgu Mures, Romania.
AD  - Emergency Institute for Cardiovascular Diseases and Transplantation - Tirgu 
      Mures, Romania.
LA  - eng
PT  - Case Reports
PL  - Romania
TA  - Acta Endocrinol (Buchar)
JT  - Acta endocrinologica (Bucharest, Romania : 2005)
JID - 101269720
PMC - PMC9206164
OTO - NOTNLM
OT  - percutaneous coronary intervention
OT  - platelet indices
OT  - type 2 diabetes mellitus
COIS- The authors declare that they have no conflict of interest.
EDAT- 2022/06/25 06:00
MHDA- 2022/06/25 06:01
PMCR- 2022/04/01
CRDT- 2022/06/24 02:21
PHST- 2022/06/24 02:21 [entrez]
PHST- 2022/06/25 06:00 [pubmed]
PHST- 2022/06/25 06:01 [medline]
PHST- 2022/04/01 00:00 [pmc-release]
AID - aeb.2021.543 [pii]
AID - 10.4183/aeb.2021.543 [doi]
PST - ppublish
SO  - Acta Endocrinol (Buchar). 2021 Oct-Dec;17(4):543-547. doi: 10.4183/aeb.2021.543.