PMID- 35757318
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2090-8865 (Print)
IS  - 2090-8873 (Electronic)
IS  - 2090-8873 (Linking)
VI  - 2022
DP  - 2022
TI  - Rapid Screening of 352 Pesticide Residues in Chrysanthemum Flower by Gas 
      Chromatography Coupled to Quadrupole-Orbitrap Mass Spectrometry with Sin-QuEChERS 
      Nanocolumn Extraction.
PG  - 7684432
LID - 10.1155/2022/7684432 [doi]
LID - 7684432
AB  - To analyze pesticide residues, GC coupled with quadrupole-Orbitrap MS 
      (GC-Orbitrap-MS) has become a powerful tool because of its unique characteristics 
      of accurate mass full-spectrum acquisition, high resolution, fast acquisition 
      rates, and overcoming matrix interference. This paper presents an efficiency 
      evaluation of GC-Orbitrap-MS for identification and quantitation in the 352 
      pesticide residues analysis of chrysanthemum flowers in full-scan mode. A 
      streamlined pretreatment approach using one-step extraction and dilution was 
      used, which provided high-throughput processing and excellent recovery. The 
      samples were extracted using acetonitrile. The extracted solution was purified by 
      a Sin-QuEChERS Nano column to suppress the matrix in chrysanthemum flowers and 
      determined by GC-Orbitrap-MS. The calibration curves for the 352 pesticides 
      obtained by GC-Orbitrap-MS were linear in the range of 0.5-200 mug.kg(-1), with 
      the correlation coefficients higher than 0.99. The limits of detection (LODs) and 
      the limits of quantification (LOQs) for the 352 pesticide residues were 
      0.3-3.0 mug.kg(-1) and 1.0-10.0 mug.kg(-1), respectively. The average recoveries in 
      chrysanthemum flower at three levels were 95.2%, 88.6%, and 95.7%, respectively, 
      with relative standard deviations (RSDs) of 7.1%, 7.5%, and 7.2%, respectively. 
      Lastly, the validated method and retrospective analysis was applied to a total of 
      200 chrysanthemum flower samples bought in local pharmacies. The proposed method 
      can simultaneously detect multipesticide residues with a good performance in 
      qualitative and quantitative detection.
CI  - Copyright (c) 2022 Yuanyuan Wang et al.
FAU - Wang, Yuanyuan
AU  - Wang Y
AUID- ORCID: 0000-0002-4684-3359
AD  - Department of Pharmacology, College of Basic Medicine, Hebei University of 
      Chinese Medicine, Shijiazhuang, 050200 Hebei, China.
FAU - Meng, Zhijuan
AU  - Meng Z
AUID- ORCID: 0000-0002-1664-1561
AD  - Hebei Food Inspection and Research Institute, Key Laboratory of Food Safety of 
      Hebei Province, Shijiazhuang, 050091 Hebei, China.
FAU - Su, Chunyan
AU  - Su C
AUID- ORCID: 0000-0001-5481-2176
AD  - School of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, 050200 
      Hebei, China.
FAU - Fan, Sufang
AU  - Fan S
AUID- ORCID: 0000-0002-5156-9251
AD  - Hebei Food Inspection and Research Institute, Key Laboratory of Food Safety of 
      Hebei Province, Shijiazhuang, 050091 Hebei, China.
FAU - Li, Yan
AU  - Li Y
AUID- ORCID: 0000-0003-1829-4185
AD  - Hebei Food Inspection and Research Institute, Key Laboratory of Food Safety of 
      Hebei Province, Shijiazhuang, 050091 Hebei, China.
FAU - Liu, Haiye
AU  - Liu H
AUID- ORCID: 0000-0002-9460-8572
AD  - Department of Pharmacology, College of Basic Medicine, Hebei University of 
      Chinese Medicine, Shijiazhuang, 050200 Hebei, China.
FAU - Zhang, Xuan
AU  - Zhang X
AUID- ORCID: 0000-0001-8989-9080
AD  - Department of Pharmacology, College of Basic Medicine, Hebei University of 
      Chinese Medicine, Shijiazhuang, 050200 Hebei, China.
FAU - Chen, Pingping
AU  - Chen P
AUID- ORCID: 0000-0001-7031-0766
AD  - Department of Pharmacology, College of Basic Medicine, Hebei University of 
      Chinese Medicine, Shijiazhuang, 050200 Hebei, China.
FAU - Geng, Yunyun
AU  - Geng Y
AUID- ORCID: 0000-0002-4781-4402
AD  - Department of Pharmacology, College of Basic Medicine, Hebei University of 
      Chinese Medicine, Shijiazhuang, 050200 Hebei, China.
FAU - Li, Qiang
AU  - Li Q
AUID- ORCID: 0000-0001-5744-1403
AD  - Hebei Food Inspection and Research Institute, Key Laboratory of Food Safety of 
      Hebei Province, Shijiazhuang, 050091 Hebei, China.
LA  - eng
PT  - Journal Article
DEP - 20220615
PL  - Egypt
TA  - J Anal Methods Chem
JT  - Journal of analytical methods in chemistry
JID - 101575377
PMC - PMC9217587
COIS- The authors declare that they have no potential conflicts of interest.
EDAT- 2022/06/28 06:00
MHDA- 2022/06/28 06:01
PMCR- 2022/06/15
CRDT- 2022/06/27 04:22
PHST- 2022/01/31 00:00 [received]
PHST- 2022/04/13 00:00 [revised]
PHST- 2022/05/10 00:00 [accepted]
PHST- 2022/06/27 04:22 [entrez]
PHST- 2022/06/28 06:00 [pubmed]
PHST- 2022/06/28 06:01 [medline]
PHST- 2022/06/15 00:00 [pmc-release]
AID - 10.1155/2022/7684432 [doi]
PST - epublish
SO  - J Anal Methods Chem. 2022 Jun 15;2022:7684432. doi: 10.1155/2022/7684432. 
      eCollection 2022.