PMID- 35757868 OWN - NLM STAT- MEDLINE DCOM- 20231216 LR - 20231216 IS - 1549-7852 (Electronic) IS - 1040-8398 (Linking) VI - 63 IP - 32 DP - 2023 TI - Effects of the ketogenic diet on performance and body composition in athletes and trained adults: a systematic review and Bayesian multivariate multilevel meta-analysis and meta-regression. PG - 11399-11424 LID - 10.1080/10408398.2022.2090894 [doi] AB - This systematic review with meta-analysis aimed to determine the effects of the ketogenic diet (KD) against carbohydrate (CHO)-rich diets on physical performance and body composition in trained individuals. The MEDLINE, EMBASE, CINAHL, SPORTDiscus, and The Cochrane Library were searched. Randomized and non-randomized controlled trials in athletes/trained adults were included. Meta-analytic models were carried out using Bayesian multilevel models. Eighteen studies were included providing estimates on cyclic exercise modes and strength one-maximum repetition (1-RM) performances and for total, fat, and free-fat masses. There were more favorable effects for CHO-rich than KD on time-trial performance (mode [95% credible interval]; -3.3% [-8.5%, 1.7%]), 1-RM (-5.7% [-14.9%, 2.6%]), and free-fat mass (-0.8 [-3.4, 1.9] kg); effects were more favorable to KD on total (-2.4 [-6.2, 1.8] kg) and fat mass losses (-2.4 [-5.4, 0.2] kg). Likely modifying effects on cyclic performance were the subject's sex and VO(2)max, intervention and performance durations, and mode of exercise. The intervention duration and subjects' sex were likely to modify effects on total body mass. KD can be a useful strategy for total and fat body losses, but a small negative effect on free-fat mass was observed. KD was not suitable for enhancing strength 1-RM or high-intensity cyclic performances. FAU - Koerich, Ana Clara C AU - Koerich ACC AD - Department of Nutrition, Health Sciences Center, Federal University of Santa Catarina, University Campus, Trindade, Florianopolis, Santa Catarina, Brazil. FAU - Borszcz, Fernando Klitzke AU - Borszcz FK AUID- ORCID: 0000-0002-3773-6906 AD - Physical Effort Laboratory, Sports Center, Federal University of Santa Catarina, University Campus, Pantanal, Florianopolis, Santa Catarina, Brazil. FAU - Thives Mello, Arthur AU - Thives Mello A AUID- ORCID: 0000-0001-5507-7249 AD - Department of Nutrition, Health Sciences Center, Federal University of Santa Catarina, University Campus, Trindade, Florianopolis, Santa Catarina, Brazil. FAU - de Lucas, Ricardo Dantas AU - de Lucas RD AUID- ORCID: 0000-0002-8566-3086 AD - Physical Effort Laboratory, Sports Center, Federal University of Santa Catarina, University Campus, Pantanal, Florianopolis, Santa Catarina, Brazil. FAU - Hansen, Fernanda AU - Hansen F AUID- ORCID: 0000-0003-4934-9572 AD - Department of Nutrition, Health Sciences Center, Federal University of Santa Catarina, University Campus, Trindade, Florianopolis, Santa Catarina, Brazil. LA - eng PT - Journal Article PT - Meta-Analysis PT - Systematic Review DEP - 20220627 PL - United States TA - Crit Rev Food Sci Nutr JT - Critical reviews in food science and nutrition JID - 8914818 RN - 0 (Dietary Carbohydrates) SB - IM MH - Adult MH - Humans MH - *Diet, Ketogenic MH - Bayes Theorem MH - Athletes MH - Dietary Carbohydrates MH - Body Composition MH - Randomized Controlled Trials as Topic OTO - NOTNLM OT - Athlete OT - body composition OT - endurance OT - ketogenic diet OT - performance OT - strength EDAT- 2022/06/28 06:00 MHDA- 2023/12/17 09:42 CRDT- 2022/06/27 04:34 PHST- 2023/12/17 09:42 [medline] PHST- 2022/06/28 06:00 [pubmed] PHST- 2022/06/27 04:34 [entrez] AID - 10.1080/10408398.2022.2090894 [doi] PST - ppublish SO - Crit Rev Food Sci Nutr. 2023;63(32):11399-11424. doi: 10.1080/10408398.2022.2090894. Epub 2022 Jun 27.