PMID- 35764487
OWN - NLM
STAT- MEDLINE
DCOM- 20221123
LR  - 20221123
IS  - 0929-6646 (Print)
IS  - 0929-6646 (Linking)
VI  - 121
IP  - 12
DP  - 2022 Dec
TI  - Mortality risk factors in patients on waiting list for lung transplantation 
      between 2005 and 2018: A single institutional experience.
PG  - 2566-2573
LID - S0929-6646(22)00244-3 [pii]
LID - 10.1016/j.jfma.2022.06.005 [doi]
AB  - BACKGROUND: Lung transplantation is a therapeutic option for patients with 
      end-stage lung disease. However, the increase in organ demand has surpassed the 
      number of donors, with many patients unable to outlive the long waiting period. 
      This study aimed to assess mortality and its risk factors in patients on the 
      waiting list for lung transplantation in a single medical centre. METHODS: All 
      evaluated clinical and laboratory data of the patients with end-stage lung 
      disease assessed for lung transplantation between February 2005 and November 2018 
      in National Taiwan University Hospital were recorded in the waiting list 
      database. The patients in this study were divided into two groups: survival and 
      death groups. RESULTS: Between February 2005 and November 2018, 169 patients were 
      enrolled in the waiting list. Thirty-one patients were alive and waiting for the 
      chance of lung transplantation, 56 underwent lung transplantation, and 82 died 
      while waiting. The mean age of all patients was 43.7 years, and 91 were women. 
      The mean body mass index (BMI) was 20.3. The most common blood type was type O. 
      All patients were in New York Heart Association (NYHA) class III or IV. After 
      analysis of the two groups, lower BMI presented as a mortality factor. 
      CONCLUSION: This is the first Taiwanese study to describe the mortality factors 
      in patients waiting for lung transplantation. The main factors influencing the 
      survival of these patients were lower BMI, NYHA class IV, and diseases which 
      cause end-stage lung diseases (infection and pulmonary fibrosis).
CI  - Copyright (c) 2022 Formosan Medical Association. Published by Elsevier B.V. All 
      rights reserved.
FAU - Chuang, Jen-Hao
AU  - Chuang JH
AD  - Department of Surgical Oncology, National Taiwan University Cancer Center, 
      Taipei, Taiwan; Department of Surgery, National Taiwan University Hospital and 
      National Taiwan University College of Medicine, Taipei, Taiwan.
FAU - Lu, Pham Huu
AU  - Lu PH
AD  - Cardiovascular and Thoracic Center, Viet Duc University Hospital, Hanoi Medical 
      University, Hanoi, Viet Nam.
FAU - Anh, Nguyen Viet
AU  - Anh NV
AD  - Cardiovascular and Thoracic Center, Viet Duc University Hospital, Hanoi Medical 
      University, Hanoi, Viet Nam.
FAU - Diep, Trinh Ke
AU  - Diep TK
AD  - Department of Anesthesiology, Viet Duc University Hospital, Hanoi Medical 
      University, Hanoi, Viet Nam.
FAU - Liu, Hao-Yun
AU  - Liu HY
AD  - Department of Surgery, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
FAU - Chiang, Xu-Heng
AU  - Chiang XH
AD  - Department of Surgery, National Taiwan University Hospital and National Taiwan 
      University College of Medicine, Taipei, Taiwan; Department of Medical Education, 
      National Taiwan University Hospital, Taipei, Taiwan.
FAU - Ho, Cheng-Maw
AU  - Ho CM
AD  - Department of Surgery, National Taiwan University Hospital and National Taiwan 
      University College of Medicine, Taipei, Taiwan.
FAU - Huang, Shu-Chien
AU  - Huang SC
AD  - Department of Surgery, National Taiwan University Hospital and National Taiwan 
      University College of Medicine, Taipei, Taiwan.
FAU - Hsu, Hsao-Hsun
AU  - Hsu HH
AD  - Department of Surgery, National Taiwan University Hospital and National Taiwan 
      University College of Medicine, Taipei, Taiwan. Electronic address: 
      ntuhsu@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20220625
PL  - Singapore
TA  - J Formos Med Assoc
JT  - Journal of the Formosan Medical Association = Taiwan yi zhi
JID - 9214933
SB  - IM
MH  - Humans
MH  - Female
MH  - Adult
MH  - Male
MH  - Waiting Lists
MH  - *Lung Transplantation
MH  - Tissue Donors
MH  - Risk Factors
MH  - *Pulmonary Fibrosis
OTO - NOTNLM
OT  - Lung
OT  - Pulmonary fibrosis
OT  - Risk factors
OT  - Tissue donors
OT  - Transplantation
COIS- Declaration of competing interest The authors declare that they have no conflicts 
      of interest.
EDAT- 2022/06/29 06:00
MHDA- 2022/11/24 06:00
CRDT- 2022/06/28 22:05
PHST- 2021/10/18 00:00 [received]
PHST- 2022/06/08 00:00 [revised]
PHST- 2022/06/09 00:00 [accepted]
PHST- 2022/06/29 06:00 [pubmed]
PHST- 2022/11/24 06:00 [medline]
PHST- 2022/06/28 22:05 [entrez]
AID - S0929-6646(22)00244-3 [pii]
AID - 10.1016/j.jfma.2022.06.005 [doi]
PST - ppublish
SO  - J Formos Med Assoc. 2022 Dec;121(12):2566-2573. doi: 10.1016/j.jfma.2022.06.005. 
      Epub 2022 Jun 25.