PMID- 35764607 OWN - NLM STAT- MEDLINE DCOM- 20220630 LR - 20230701 IS - 2058-6124 (Electronic) IS - 2058-6124 (Linking) VI - 8 IP - 1 DP - 2022 Jun 28 TI - Successful pregnancy and cesarean delivery in a tetraplegic, home-invasively-mechanically-ventilated patient - case report. PG - 62 LID - 10.1038/s41394-022-00528-4 [doi] LID - 62 AB - INTRODUCTION: Pregnancies are rare in patients with severely disabilitating spinal cord injuries (SCI) but increasing alongside social awareness concerning reproductive equality. Physicians should be aware of several potential complications during pregnancy and delivery, particularly autonomic dysreflexia. CASE PRESENTATION: We report a successful pregnancy of a 32-year-old woman with a severe SCI at the C2 level (C1-4 ASIA Impairment Scale grade A) and total dependency on home invasive mechanical ventilation (HIMV), an extremely rare treatment. An elective cesarean section was chosen as the delivery mode at 34 + 0 weeks of gestation. Both the mother and the child recovered well. DISCUSSION: Severe spinal cord injury and dependency on mechanical ventilation are not absolute contraindications for pregnancy. With careful planning, pregnancy is possible also for patients with the most severe forms of SCI. Adequate pain relief during cesarean delivery is required despite complete spinal cord injury in order to avoid excessive hemodynamic responses and spinal reflexes. A multidisciplinary team is needed to ensure safe pregnancy and delivery of these high-risk pregnancies. CI - (c) 2022. The Author(s), under exclusive licence to International Spinal Cord Society. FAU - Jernman, Riina AU - Jernman R AD - Helsinki University Hospital, Obstetrics and Gynecology, Helsinki, Finland. riina.jernman@hus.fi. FAU - Vaananen, Antti AU - Vaananen A AD - Helsinki University Hospital, Anesthesiology and Intensive Care, Helsinki, Finland. FAU - Kreivi, Hanna-Riikka AU - Kreivi HR AD - Helsinki University Hospital, Heart and Lung Center, Pulmonary Medicine, Helsinki, Finland. LA - eng PT - Case Reports PT - Journal Article DEP - 20220628 PL - England TA - Spinal Cord Ser Cases JT - Spinal cord series and cases JID - 101680856 SB - IM MH - Adult MH - *Autonomic Dysreflexia MH - Cesarean Section MH - Child MH - Family MH - Female MH - Humans MH - Pregnancy MH - Respiration, Artificial MH - *Spinal Cord Injuries/complications PMC - PMC9240012 COIS- The authors declare no competing interests. EDAT- 2022/06/29 06:00 MHDA- 2022/07/01 06:00 PMCR- 2023/06/28 CRDT- 2022/06/28 23:13 PHST- 2022/02/10 00:00 [received] PHST- 2022/06/09 00:00 [accepted] PHST- 2022/06/07 00:00 [revised] PHST- 2022/06/28 23:13 [entrez] PHST- 2022/06/29 06:00 [pubmed] PHST- 2022/07/01 06:00 [medline] PHST- 2023/06/28 00:00 [pmc-release] AID - 10.1038/s41394-022-00528-4 [pii] AID - 528 [pii] AID - 10.1038/s41394-022-00528-4 [doi] PST - epublish SO - Spinal Cord Ser Cases. 2022 Jun 28;8(1):62. doi: 10.1038/s41394-022-00528-4.