PMID- 35770358
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2234-7550 (Print)
IS  - 2234-5930 (Electronic)
IS  - 1225-1585 (Linking)
VI  - 48
IP  - 3
DP  - 2022 Jun 30
TI  - Minimal clinically important difference of mouth opening in oral submucous 
      fibrosis patients: a retrospective study.
PG  - 167-173
LID - 10.5125/jkaoms.2022.48.3.167 [doi]
AB  - OBJECTIVES: The purpose of this study was to estimate the minimal clinically 
      important difference (MCID) of mouth opening (MO) and patient satisfaction in 
      surgically treated oral submucous fibrosis (OSMF) patients. MATERIALS AND 
      METHODS: The status of MO was collected preoperatively (T0), postoperatively at 3 
      months (T1), and at a minimum of 6 months postoperatively (T2). MCID was 
      determined through the anchor-based approach with the change difference method, 
      mean change method, and receiver operator characteristic curve (ROC) method. 
      RESULTS: In this study, 35 patients enrolled and completed postoperative 
      follow-up (T2) averaging a duration of 18.1 months. At T1, using the change 
      difference method, MO was 14.89 mm and the ROC curve exhibited a 11.5 gain in MO 
      (sensitivity 81.8% and specificity 100%, area under the curve [AUC] of 0.902) and 
      was classified as MCID as reported by patients. At T2, MCID of MO was 9.75 mm 
      using the change difference method and 11.75 mm by the mean change method. The 
      ROC curve revealed that the MCID of MO at T2 was 10.5 mm with 73.9% sensitivity 
      and 83.3% specificity (AUC of 0.873). The kappa value was 0.91, confirming 
      reliability of the data. CONCLUSION: This study demonstrated MCID values that 
      indicate the clinical relevance of surgical treatment of OSMF if the minimum 
      possible gain in MO is approximately 10 mm.
FAU - Kaur, Amanjot
AU  - Kaur A
AUID- ORCID: 0000-0001-5560-0140
AD  - Oral and Maxillofacial Surgery, Department of Dentistry, All India Institute of 
      Medical Sciences (AIIMS), Jodhpur, India.
FAU - Rustagi, Neeti
AU  - Rustagi N
AUID- ORCID: 0000-0003-3051-5411
AD  - Department of Community Medicine and Family Medicine, All India Institute of 
      Medical Sciences (AIIMS), Jodhpur, India.
FAU - Ganesan, Aparna
AU  - Ganesan A
AUID- ORCID: 0000-0002-4249-2651
AD  - Oral and Maxillofacial Surgery, Department of Dentistry, All India Institute of 
      Medical Sciences (AIIMS), Jodhpur, India.
FAU - Pm, Nihadha
AU  - Pm N
AUID- ORCID: 0000-0002-0498-564X
AD  - Oral and Maxillofacial Surgery, Department of Dentistry, All India Institute of 
      Medical Sciences (AIIMS), Jodhpur, India.
FAU - Kumar, Pravin
AU  - Kumar P
AUID- ORCID: 0000-0001-9318-9188
AD  - Oral and Maxillofacial Surgery, Department of Dentistry, All India Institute of 
      Medical Sciences (AIIMS), Jodhpur, India.
FAU - Chaudhry, Kirti
AU  - Chaudhry K
AUID- ORCID: 0000-0002-8261-7033
AD  - Oral and Maxillofacial Surgery, Department of Dentistry, All India Institute of 
      Medical Sciences (AIIMS), Jodhpur, India.
LA  - eng
PT  - Journal Article
PL  - Korea (South)
TA  - J Korean Assoc Oral Maxillofac Surg
JT  - Journal of the Korean Association of Oral and Maxillofacial Surgeons
JID - 101580242
PMC - PMC9247444
OTO - NOTNLM
OT  - Minimal clinically important difference
OT  - Oral submucous fibrosis
COIS- Conflict of Interest No potential conflict of interest relevant to this article 
      was reported.
EDAT- 2022/07/01 06:00
MHDA- 2022/07/01 06:01
PMCR- 2022/06/30
CRDT- 2022/06/30 03:03
PHST- 2022/04/04 00:00 [received]
PHST- 2022/05/04 00:00 [accepted]
PHST- 2022/06/30 03:03 [entrez]
PHST- 2022/07/01 06:00 [pubmed]
PHST- 2022/07/01 06:01 [medline]
PHST- 2022/06/30 00:00 [pmc-release]
AID - jkaoms.2022.48.3.167 [pii]
AID - jkaoms-48-3-167 [pii]
AID - 10.5125/jkaoms.2022.48.3.167 [doi]
PST - ppublish
SO  - J Korean Assoc Oral Maxillofac Surg. 2022 Jun 30;48(3):167-173. doi: 
      10.5125/jkaoms.2022.48.3.167.