PMID- 35778927
OWN - NLM
STAT- MEDLINE
DCOM- 20230123
LR  - 20230123
IS  - 1443-1661 (Electronic)
IS  - 0915-5635 (Linking)
VI  - 35
IP  - 2
DP  - 2023 Jan
TI  - Clinical and technical outcomes of endoscopic closure of postendoscopic 
      submucosal dissection defects: Literature review over one decade.
PG  - 216-231
LID - 10.1111/den.14397 [doi]
AB  - Endoscopic submucosal dissection (ESD), which enables curative en bloc resection 
      of early gastrointestinal neoplasms, has been an attractive minimally invasive 
      surgery during the past two decades. Large post-ESD defects must be carefully 
      managed to prevent adverse events (AEs). The major AEs comprise delayed bleeding 
      (DB) and delayed perforation (DP), and overall AEs comprise DB plus DP. This 
      review aimed to clarify the clinical efficacy and technical outcomes of 
      endoscopic prophylactic closure for post-ESD defects. We identified studies 
      involving >/=10 patients up to March 2022 in which endoscopic closure was applied 
      for gastric, duodenal, and colorectal post-ESD defects. In the stomach, total 
      rates of overall AEs and DB were significantly lower in the closure than 
      non-closure group. In the duodenum, total rates of overall AEs, DB, and DP were 
      significantly lower in the closure group. In the colorectum, total rates of 
      overall AEs and DB were significantly lower in the closure group. Closure 
      techniques, categorized into three groups (clip-based techniques, mechanical 
      clipping, and surgical stitch-based techniques), were illustrated. Endoscopic 
      closure demonstrated a certain ability to reduce DB after gastric, duodenal, and 
      colorectal ESD as well as DP after duodenal ESD. Considering closure-associated 
      costs, the indications and limitations of closure techniques should be further 
      investigated.
CI  - (c) 2022 Japan Gastroenterological Endoscopy Society.
FAU - Kobara, Hideki
AU  - Kobara H
AUID- ORCID: 0000-0002-8508-827X
AD  - Departments of Gastroenterology and Neurology, Faculty of Medicine, Kagawa 
      University, Kagawa, Japan.
FAU - Tada, Naoya
AU  - Tada N
AD  - Departments of Gastroenterology and Neurology, Faculty of Medicine, Kagawa 
      University, Kagawa, Japan.
FAU - Fujihara, Shintaro
AU  - Fujihara S
AD  - Departments of Gastroenterology and Neurology, Faculty of Medicine, Kagawa 
      University, Kagawa, Japan.
FAU - Nishiyama, Noriko
AU  - Nishiyama N
AD  - Departments of Gastroenterology and Neurology, Faculty of Medicine, Kagawa 
      University, Kagawa, Japan.
FAU - Masaki, Tsutomu
AU  - Masaki T
AD  - Departments of Gastroenterology and Neurology, Faculty of Medicine, Kagawa 
      University, Kagawa, Japan.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220825
PL  - Australia
TA  - Dig Endosc
JT  - Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy 
      Society
JID - 9101419
SB  - IM
MH  - Humans
MH  - Retrospective Studies
MH  - Endoscopy
MH  - Dissection/methods
MH  - *Gastrointestinal Neoplasms/surgery
MH  - *Endoscopic Mucosal Resection/adverse effects/methods
MH  - Treatment Outcome
MH  - *Colorectal Neoplasms/surgery
OTO - NOTNLM
OT  - clip
OT  - endoscopic submucosal dissection
OT  - gastrointestinal neoplasm
OT  - hemorrhage
OT  - suture
EDAT- 2022/07/03 06:00
MHDA- 2023/01/24 06:00
CRDT- 2022/07/02 03:52
PHST- 2022/05/10 00:00 [received]
PHST- 2022/06/30 00:00 [accepted]
PHST- 2022/07/03 06:00 [pubmed]
PHST- 2023/01/24 06:00 [medline]
PHST- 2022/07/02 03:52 [entrez]
AID - 10.1111/den.14397 [doi]
PST - ppublish
SO  - Dig Endosc. 2023 Jan;35(2):216-231. doi: 10.1111/den.14397. Epub 2022 Aug 25.