PMID- 3578006
OWN - NLM
STAT- MEDLINE
DCOM- 19870602
LR  - 20190626
IS  - 0002-8703 (Print)
IS  - 0002-8703 (Linking)
VI  - 113
IP  - 5
DP  - 1987 May
TI  - Segmental wall motion abnormalities in dilated cardiomyopathy: hemodynamic 
      characteristics and comparison with thallium-201 myocardial scintigraphy.
PG  - 1123-8
AB  - This study assessed the hemodynamic characteristics of segmental wall motion 
      abnormality of the left ventricle in patients with dilated cardiomyopathy (DCM) 
      and its relation to the thallium-201 (TI-201) myocardial scintigraphy (MPI). Left 
      ventriculograms and MPI in 23 patients were analyzed by the use of quantitative 
      indexes of regional wall motion and TI-201 uptake based on a mean and a standard 
      deviation of 13 normal subjects. Relative normokinesis in our definition was more 
      frequently seen in the inferior wall than in the anterior wall (p less than 
      0.01). In contrast, severe asynergy was more often seen in the anterior wall than 
      in the inferior wall (p less than 0.01). There were 11 patients who had relative 
      normokinesis and asynergy together. By means of the index of wall motion, the DCM 
      patients were divided into two groups, one with segmental wall motion abnormality 
      (SWMA) and another with diffuse wall motion abnormality (DWMA). The DWMA group 
      had higher left ventricular end-diastolic pressures (p less than 0.05) and the 
      tendency of large left ventricular end-diastolic volumes than the SWMA group. 
      There was a rough correlation (r = 0.58) between the quantitative indexes of 
      TI-201 uptake and wall motion at the same region of the left ventricle. Thus, the 
      nonuniformity of the left ventricular wall motion was recognized in the patients 
      with DCM and more increased preload was shown in the patients with DWMA than in 
      the group with SWMA. Further, the regional asynergy may be related to the 
      localized fibrosis within the left ventricle in DCM, considering the result that 
      the worse TI-201 uptake was roughly accompanied by the more severe asynergy.
FAU - Yamaguchi, S
AU  - Yamaguchi S
FAU - Tsuiki, K
AU  - Tsuiki K
FAU - Hayasaka, M
AU  - Hayasaka M
FAU - Yasui, S
AU  - Yasui S
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Am Heart J
JT  - American heart journal
JID - 0370465
RN  - 0 (Radioisotopes)
RN  - AD84R52XLF (Thallium)
SB  - IM
MH  - Adult
MH  - Cardiac Catheterization
MH  - Cardiomyopathy, Dilated/*diagnostic imaging/physiopathology
MH  - Cineangiography
MH  - Female
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Myocardial Contraction
MH  - Radioisotopes
MH  - Radionuclide Imaging
MH  - Thallium
EDAT- 1987/05/01 00:00
MHDA- 1987/05/01 00:01
CRDT- 1987/05/01 00:00
PHST- 1987/05/01 00:00 [pubmed]
PHST- 1987/05/01 00:01 [medline]
PHST- 1987/05/01 00:00 [entrez]
AID - 0002-8703(87)90922-7 [pii]
AID - 10.1016/0002-8703(87)90922-7 [doi]
PST - ppublish
SO  - Am Heart J. 1987 May;113(5):1123-8. doi: 10.1016/0002-8703(87)90922-7.