PMID- 35780098
OWN - NLM
STAT- MEDLINE
DCOM- 20220706
LR  - 20220716
IS  - 1471-2415 (Electronic)
IS  - 1471-2415 (Linking)
VI  - 22
IP  - 1
DP  - 2022 Jul 2
TI  - Refractive error characteristics and influence on ocular parameters in patients 
      with unilateral congenital ptosis.
PG  - 291
LID - 10.1186/s12886-022-02511-x [doi]
LID - 291
AB  - BACKGROUND: The study aimed to investigate the difference in refractive status 
      and ocular parameters between ptotic and fellow eyes in patients with unilateral 
      congenital ptosis. METHODS: Thirty patients (53% males, age 22.00 +/- 11.41 years) 
      with unilateral congenital ptosis diagnosed and treated at the First Affiliated 
      Hospital of Sun-yat Sen University were enrolled and underwent detailed 
      refractive examinations from March 2019 to February 2022. Ocular biometric 
      measurements were performed by an IOL Master 700 biometer. The differences in 
      refractive error characteristics, best-corrected visual acuity (BCVA), and ocular 
      parameters including axial length (AL), central corneal thickness (CCT), aqueous 
      depth (AQD), anterior chamber depth (ACD), lens thickness (LT), and keratometry 
      values between ptotic and fellow eyes were analysed. RESULTS: A lower BCVA 
      (logMAR, median (IQR), 0.00 (- 0.13,0.00), P = 0.009) and a higher incidence of 
      amblyopia (n (%), 7(23%), P = 0.016) were observed in ptotic eyes. The CCT of 
      ptotic eyes was greater than that of fellow eyes (mean +/- SD, 539.83 +/- 26.73 mum, 
      P < 0.001). The keratometry values at the flat axis (K1) and mean corneal power 
      (Km) were smaller in ptotic eyes (mean +/- SD, 42.11 +/- 1.49 D, 42.68 +/- 1.52 D, 
      respectively, both P = 0.001). There was no significant difference in AL between 
      ptotic and fellow eyes. CONCLUSIONS: Congenital ptosis influences ocular 
      parameters, mainly causing a thicker and flatter cornea. Patients with unilateral 
      congenital ptosis might have lower BCVA in the ptotic eyes.
CI  - (c) 2022. The Author(s).
FAU - Liu, Yingli
AU  - Liu Y
AD  - Department of Ophthalmology, First Affiliated Hospital of Sun Yat-sen University, 
      58 Zhongshan 2nd Road, Yuexiu District, Guangzhou, Guangdong Province, 510080, P. 
      R. China.
FAU - Chen, Tingting
AU  - Chen T
AD  - Department of Ophthalmology, First Affiliated Hospital of Sun Yat-sen University, 
      58 Zhongshan 2nd Road, Yuexiu District, Guangzhou, Guangdong Province, 510080, P. 
      R. China.
FAU - Huang, Jingwen
AU  - Huang J
AD  - Department of Ophthalmology, First Affiliated Hospital of Sun Yat-sen University, 
      58 Zhongshan 2nd Road, Yuexiu District, Guangzhou, Guangdong Province, 510080, P. 
      R. China.
FAU - Li, Wentao
AU  - Li W
AD  - Department of Ophthalmology, First Affiliated Hospital of Sun Yat-sen University, 
      58 Zhongshan 2nd Road, Yuexiu District, Guangzhou, Guangdong Province, 510080, P. 
      R. China.
FAU - Chen, Yilin
AU  - Chen Y
AD  - Department of Ophthalmology, First Affiliated Hospital of Sun Yat-sen University, 
      58 Zhongshan 2nd Road, Yuexiu District, Guangzhou, Guangdong Province, 510080, P. 
      R. China.
FAU - Huo, Lijun
AU  - Huo L
AD  - Department of Ophthalmology, First Affiliated Hospital of Sun Yat-sen University, 
      58 Zhongshan 2nd Road, Yuexiu District, Guangzhou, Guangdong Province, 510080, P. 
      R. China. huolijun@mail.sysu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20220702
PL  - England
TA  - BMC Ophthalmol
JT  - BMC ophthalmology
JID - 100967802
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Amblyopia
MH  - *Blepharoptosis/congenital
MH  - Child
MH  - Cornea
MH  - Female
MH  - Humans
MH  - Male
MH  - Refraction, Ocular
MH  - *Refractive Errors
MH  - Young Adult
PMC - PMC9250722
OTO - NOTNLM
OT  - Congenital ptosis
OT  - IOL master700
OT  - Ocular parameters
OT  - Refractive error
COIS- The authors declare that they have no competing interests.
EDAT- 2022/07/03 06:00
MHDA- 2022/07/07 06:00
PMCR- 2022/07/02
CRDT- 2022/07/02 23:14
PHST- 2022/03/06 00:00 [received]
PHST- 2022/06/23 00:00 [accepted]
PHST- 2022/07/02 23:14 [entrez]
PHST- 2022/07/03 06:00 [pubmed]
PHST- 2022/07/07 06:00 [medline]
PHST- 2022/07/02 00:00 [pmc-release]
AID - 10.1186/s12886-022-02511-x [pii]
AID - 2511 [pii]
AID - 10.1186/s12886-022-02511-x [doi]
PST - epublish
SO  - BMC Ophthalmol. 2022 Jul 2;22(1):291. doi: 10.1186/s12886-022-02511-x.