PMID- 35782373 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220716 IS - 2757-7392 (Electronic) IS - 1307-5888 (Print) IS - 2757-7392 (Linking) VI - 3 IP - 1 DP - 2022 Jan TI - Graft versus host disease after liver transplantation: A case report. PG - 30-32 LID - 10.14744/hf.2021.2021.0006 [doi] AB - Graft Versus Host Disease (GVHD) is a severe immunological-clinicopathological condition mediated by healthy T-lymphocytes in donor tissue against the immunosuppressed host tissue and rarely seen after solid organ transplantation (SOT). A 72-year old male patient underwent cadaveric liver transplantation. On day 34 of the postoperative follow-up, the patient developed fever, generalized skin rash and hemorrhagic lesions in the oropharynx. Skin biopsy was consistent with GVHD. Despite high-dose corticosteroid treatment, he died on postoperative day 51. Although it is seen rarely after liver transplantation, GVHD is an important clinical entity for which early diagnosis is critical due to its high rates of mortality. CI - (c) Copyright 2022 by Hepatology Forum - Available online at www.hepatologyforum.org. FAU - Acar, Sencan AU - Acar S AUID- ORCID: 0000-0001-8086-0956 AD - Department of Gastroenterology and Organ Transplantation Center, Sakarya University Faculty of Medicine, Sakarya, Turkey. FAU - Arat, Mutlu AU - Arat M AUID- ORCID: 0000-0003-2039-8557 AD - Department of Haematology and Bone Marrow Transplantation Unit, Bilim University Faculty of Medicine, Sisli Florence Nightingale Hospital, Istanbul, Turkey. FAU - Tecimer, Tulay AU - Tecimer T AUID- ORCID: 0000-0003-3891-7570 AD - Department of Pathology, Acibadem University Fculty of Medicine and Nisantasi Pathology Center, Istanbul, Turkey. FAU - Yalcin Polat, Kamil AU - Yalcin Polat K AUID- ORCID: 0000-0002-2840-2429 AD - Department of General Surgery and Organ Transplantation Center, Memorial Atasehir Hospital, Istanbul, Turkey. FAU - Akyildiz, Murat AU - Akyildiz M AUID- ORCID: 0000-0002-2080-7528 AD - Department of Gastroenterology and Organ Transplantation Center, Koc University Faculty of Medicine. Istanbul, Turkey. LA - eng PT - Case Reports DEP - 20220110 PL - Turkey TA - Hepatol Forum JT - Hepatology forum JID - 9918351171306676 PMC - PMC9138908 OTO - NOTNLM OT - Graft versus host disease OT - hemorrhagic lesions OT - liver transplantation OT - pancytopenia OT - rash COIS- Conflict of Interest: The authors have no conflict of interest to declare. EDAT- 2022/07/06 06:00 MHDA- 2022/07/06 06:01 PMCR- 2022/01/10 CRDT- 2022/07/05 09:50 PHST- 2021/03/01 00:00 [received] PHST- 2021/12/23 00:00 [accepted] PHST- 2022/07/05 09:50 [entrez] PHST- 2022/07/06 06:00 [pubmed] PHST- 2022/07/06 06:01 [medline] PHST- 2022/01/10 00:00 [pmc-release] AID - hf-3-30 [pii] AID - 10.14744/hf.2021.2021.0006 [doi] PST - epublish SO - Hepatol Forum. 2022 Jan 10;3(1):30-32. doi: 10.14744/hf.2021.2021.0006. eCollection 2022 Jan.