PMID- 35786240
OWN - NLM
STAT- MEDLINE
DCOM- 20220728
LR  - 20221015
IS  - 1747-4094 (Electronic)
IS  - 1747-4094 (Linking)
VI  - 15
IP  - 7
DP  - 2022 Jul
TI  - Hematological parameters and X-ray exposure among medical radiation workers: a 
      systematic review and meta-analysis.
PG  - 645-656
LID - 10.1080/17474086.2022.2096001 [doi]
AB  - BACKGROUND: The aim of this study was to explore the effect of occupational 
      exposure to X-ray on hematological parameters. RESEARCH DESIGN AND METHODS: A 
      systematic search was conducted in the Scopus, PubMed, Web of Science, and Embase 
      databases up to April 2020. The methodological quality was assessed by Joanna 
      Briggs Institute (JBI) Critical Appraisal Checklist . The random-effects model 
      was used to estimate the effect size (standard difference in means (SDMs)). 
      RESULTS: Out of 1750 identified citations, ten studies met the inclusion criteria 
      The overall effect size did not show any significant difference between the two 
      groups (SMDs ranged from -0.382 +/- 0.29 for white blood cells (WBC), 0.213 +/- 0.40 
      for platelet, -0.323 +/- 0.0.16 for mean corpuscular volume (MCV), 0.553 +/- 0.41 for 
      mean corpuscular hemoglobin concentration (MCHC), -1.615 +/- 1.41 for monocyte, 
      0.418 +/- 0.49 for lymphocyte (P-value>0.05). Only the effect size of red blood 
      cells was significantly higher than that of the control group (SMD = 1.06 +/- 0.28; 
      95% CI: 0.504, 1.615; P-value = 0.001). CONCLUSION: The long-term and low-dose 
      radiation may have no significant effect on blood parameters. Future studies are 
      suggested to use other tests such as dicentric chromosome assay (DCA), 
      cytogenetic tests, and modern tests besides blood count parameters.
FAU - Vaziri, Siavash
AU  - Vaziri S
AUID- ORCID: 0000-0002-3907-6155
AD  - Department of Infectious Diseases, School of Medicine, Kermanshah University of 
      Medical Sciences, Kermanshah, Iran.
FAU - Mirzaei, Maryam
AU  - Mirzaei M
AUID- ORCID: 0000-0001-7908-6035
AD  - School of Rehabilitation Sciences, Kermanshah University of Medical Sciences, 
      Kermanshah, Iran.
FAU - Saba, Fakhredin
AU  - Saba F
AUID- ORCID: 0000-0002-7554-8201
AD  - Department of Medical Laboratory Science, School of Paramedical Sciences, 
      Kermanshah University of Medical Sciences, Kermanshah, Iran.
FAU - Salehi Zahabi, Kharaman
AU  - Salehi Zahabi K
AD  - Clinical Research Development Center, Taleghani and Imam Ali Hospitals, 
      Kermanshah University of Medical Sciences, Kermanshah, Iran.
FAU - Salehi Zahabi, Saleh
AU  - Salehi Zahabi S
AUID- ORCID: 0000-0002-2199-699X
AD  - Clinical Research Development Center, Taleghani and Imam Ali Hospitals, 
      Kermanshah University of Medical Sciences, Kermanshah, Iran.
AD  - Radiology and Nuclear Medicine Department, Kermanshah University of Medical 
      Sciences, Kermanshah, Iran.
FAU - Arab-Zozani, Morteza
AU  - Arab-Zozani M
AUID- ORCID: 0000-0001-7223-6707
AD  - Social Determinants of Health Research Center, Birjand University of Medical 
      Sciences, Birjand, Iran.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PT  - Systematic Review
DEP - 20220714
PL  - England
TA  - Expert Rev Hematol
JT  - Expert review of hematology
JID - 101485942
SB  - IM
MH  - *Health Personnel
MH  - Humans
MH  - X-Rays
OTO - NOTNLM
OT  - Blood cells
OT  - meta-analysis
OT  - occupation
OT  - radiation
OT  - systematic review
EDAT- 2022/07/06 06:00
MHDA- 2022/07/29 06:00
CRDT- 2022/07/05 13:16
PHST- 2022/07/06 06:00 [pubmed]
PHST- 2022/07/29 06:00 [medline]
PHST- 2022/07/05 13:16 [entrez]
AID - 10.1080/17474086.2022.2096001 [doi]
PST - ppublish
SO  - Expert Rev Hematol. 2022 Jul;15(7):645-656. doi: 10.1080/17474086.2022.2096001. 
      Epub 2022 Jul 14.