PMID- 35786582
OWN - NLM
STAT- MEDLINE
DCOM- 20220707
LR  - 20221103
IS  - 2548-0839 (Electronic)
IS  - 2548-0839 (Linking)
VI  - 7
IP  - 2
DP  - 2022 Jun
TI  - Diabetes Mellitus Affects the Microhardness of Root Dentine: An in-vitro Study.
PG  - 122-128
LID - 10.14744/eej.2022.37029 [doi]
AB  - OBJECTIVE: This study was undertaken to compare microhardness and erosion 
      susceptibility of root dentine in teeth extracted from diabetic and non-diabetic 
      donors after the application of different root canal irrigants. METHODS: 
      Forty-eight single-rooted premolars with single canals (24 each from diabetic and 
      non-diabetic) were selected, and root canals were shaped by using rotary ProTaper 
      files. Dentine slices of 4 mm were transversely sectioned from the middle root 
      third. Specimens were assigned to four subgroups (n=6) and irrigated for 5 
      minutes: 1) 2.6% sodium hypochlorite (NaOCl); 2) 17% ethylenediaminetetraacetic 
      acid (EDTA); 3) 2% chlorhexidine (CHX); and 4) normal saline. Surface 
      microhardness was determined at 100- and 500-microm depths from the pulp-dentine 
      interface. Scanning electron microscope (SEM) was used to determine the severity 
      of dentine erosion. Data were analyzed by using two-way ANOVA, Post-hoc Tukey's, 
      and Chi-square tests (P<0.05). RESULTS: Diabetes as well as NaOCl and EDTA 
      decreased surface microhardness of dentine significantly (P<0.05). Diabetes had 
      little effect on the erosion susceptibility of dentine (P>0.05). CONCLUSION: Root 
      canal irrigants can significantly lower the microhardness; specifically, in 
      diabetic patients, and may be a factor affecting the longevity of root 
      canal-treated teeth.
FAU - Saghiri, Mohammad Ali
AU  - Saghiri MA
AD  - Department of Restorative Dentistry, Rutgers Faculty of Dental Medicine, New 
      Jersey, USA / Department of Endodontics, University of the Pacific, Arthur A. 
      Dugoni Faculty of Dentistry, California, USA.
FAU - Rahmani, Behnam
AU  - Rahmani B
AD  - Sector of Angiogenesis Regenerative Medicine, Dr. Hajar Afsar Lajevardi Research 
      Group (ADMD), New Jersey, USA.
FAU - Conte, Michael
AU  - Conte M
AD  - Department of Restorative Dentistry, Clinical Affairs, Rutgers Faculty of Dental 
      Medicine, New Jersey, USA.
FAU - Nath, Devyani
AU  - Nath D
AD  - Department of Restorative Dentistry, Biomaterials and Prosthodontics Laboratory, 
      Rutgers Faculty of Dental Medicine, New Jersey, USA.
FAU - Peters, Ove
AU  - Peters O
AD  - Department of Endodontics, University of the Pacific, Arthur A. Dugoni Faculty of 
      Dentistry, California, USA; Oral Health Centre, University of Queensland, 
      Brisbane, Australia.
FAU - Morgano, Steven
AU  - Morgano S
AD  - Department of Restorative Dentistry, Rutgers Faculty of Dental Medicine, New 
      Jersey, USA.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Turkey
TA  - Eur Endod J
JT  - European endodontic journal
JID - 101717480
RN  - 0 (Root Canal Irrigants)
RN  - 9G34HU7RV0 (Edetic Acid)
SB  - IM
MH  - Dental Pulp Cavity
MH  - Dentin
MH  - *Diabetes Mellitus
MH  - Edetic Acid/pharmacology
MH  - Humans
MH  - *Root Canal Irrigants/pharmacology
PMC - PMC9285991
COIS- The authors deny any conflict of interest.
EDAT- 2022/07/06 06:00
MHDA- 2022/07/08 06:00
PMCR- 2022/06/15
CRDT- 2022/07/05 13:34
PHST- 2022/07/05 13:34 [entrez]
PHST- 2022/07/06 06:00 [pubmed]
PHST- 2022/07/08 06:00 [medline]
PHST- 2022/06/15 00:00 [pmc-release]
AID - EEJ-7-122 [pii]
AID - 10.14744/eej.2022.37029 [doi]
PST - ppublish
SO  - Eur Endod J. 2022 Jun;7(2):122-128. doi: 10.14744/eej.2022.37029.