PMID- 35787960
OWN - NLM
STAT- MEDLINE
DCOM- 20221005
LR  - 20221214
IS  - 1878-8769 (Electronic)
IS  - 1878-8750 (Linking)
VI  - 166
DP  - 2022 Oct
TI  - Utility of Postoperative Imaging Software for Deep Brain Stimulation Targeting in 
      Patients with Movement Disorders.
PG  - e163-e176
LID - S1878-8750(22)00916-0 [pii]
LID - 10.1016/j.wneu.2022.06.132 [doi]
AB  - OBJECTIVE: The objective of this study was to evaluate the accuracy of the 
      SureTune3 postoperative imaging software in determining the location of a deep 
      brain stimulation (DBS) electrode based on clinical outcomes and the adverse 
      effects (AEs) observed. METHODS: Twenty-six consecutive patients with Parkinson 
      disease (n = 17), essential tremor (n = 8), and dystonia (n = 1) who underwent 
      bilateral DBS surgery (52 electrodes) were included in this study. Presurgical 
      assessments were performed in all patients prior to surgery and at 3 and 6 months 
      after surgery, using quality-of-life and clinical scales in each case. The 
      SureTune3 software was used to evaluate the anatomical positioning of the DBS 
      electrodes. RESULTS: Following DBS surgery, motor and quality-of-life improvement 
      was observed in all patients. Different AEs were detected in 12 patients, in 10 
      of whom (83.3%) SureTune3 related the symptoms to the positioning of an 
      electrode. A clinical association was observed with SureTune3 for 48 of 52 
      (92.3%) electrodes, whereas no association was found between the AEs or clinical 
      outcomes and the SureTune3 reconstructions for 4 of 52 electrodes (7.7%) from 4 
      different patients. In 2 patients, the contact chosen was modified based on the 
      SureTune3 data, and in 2 cases, the software helped determine that second 
      electrode replacement surgery was necessary. CONCLUSIONS: The anatomical position 
      of electrodes analyzed with SureTune3 software was strongly correlated with both 
      the AEs and clinical outcomes. Thus, SureTune3 may be useful in clinical 
      practice, and it could help improve stimulation parameters and influence 
      decisions to undertake electrode replacement surgery.
CI  - Copyright (c) 2022 Elsevier Inc. All rights reserved.
FAU - Sanchez-Gomez, Almudena
AU  - Sanchez-Gomez A
AD  - Institut de Neurociencies, Service of Neurology, Parkinson's Disease and Movement 
      Disorders Unit., Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain; 
      Institut de Neurociencies, Maeztu Center, Universitat de Barcelona, Barcelona, 
      Catalonia, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer 
      (IDIBAPS), Barcelona, Catalonia, Spain.
FAU - Camargo, Paola
AU  - Camargo P
AD  - Institut de Neurociencies, Service of Neurology, Parkinson's Disease and Movement 
      Disorders Unit., Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain; 
      Institut de Neurociencies, Maeztu Center, Universitat de Barcelona, Barcelona, 
      Catalonia, Spain.
FAU - Camara, Ana
AU  - Camara A
AD  - Institut de Neurociencies, Service of Neurology, Parkinson's Disease and Movement 
      Disorders Unit., Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain; 
      Institut de Neurociencies, Maeztu Center, Universitat de Barcelona, Barcelona, 
      Catalonia, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer 
      (IDIBAPS), Barcelona, Catalonia, Spain.
FAU - Roldan, Pedro
AU  - Roldan P
AD  - Institut de Neurociencies, Maeztu Center, Universitat de Barcelona, Barcelona, 
      Catalonia, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer 
      (IDIBAPS), Barcelona, Catalonia, Spain; Institut de Neurociencies, Service of 
      Neurosurgery, Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain.
FAU - Rumia, Jordi
AU  - Rumia J
AD  - Institut de Neurociencies, Maeztu Center, Universitat de Barcelona, Barcelona, 
      Catalonia, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer 
      (IDIBAPS), Barcelona, Catalonia, Spain; Institut de Neurociencies, Service of 
      Neurosurgery, Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain.
FAU - Compta, Yaroslau
AU  - Compta Y
AD  - Institut de Neurociencies, Service of Neurology, Parkinson's Disease and Movement 
      Disorders Unit., Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain; 
      Institut de Neurociencies, Maeztu Center, Universitat de Barcelona, Barcelona, 
      Catalonia, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer 
      (IDIBAPS), Barcelona, Catalonia, Spain.
FAU - Carbayo, Alvaro
AU  - Carbayo A
AD  - Institut de Neurociencies, Service of Neurology, Parkinson's Disease and Movement 
      Disorders Unit., Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain; 
      Institut de Neurociencies, Maeztu Center, Universitat de Barcelona, Barcelona, 
      Catalonia, Spain.
FAU - Marti, Maria Jose
AU  - Marti MJ
AD  - Institut de Neurociencies, Service of Neurology, Parkinson's Disease and Movement 
      Disorders Unit., Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain; 
      Institut de Neurociencies, Maeztu Center, Universitat de Barcelona, Barcelona, 
      Catalonia, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer 
      (IDIBAPS), Barcelona, Catalonia, Spain.
FAU - Munoz, Esteban
AU  - Munoz E
AD  - Institut de Neurociencies, Service of Neurology, Parkinson's Disease and Movement 
      Disorders Unit., Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain; 
      Institut de Neurociencies, Maeztu Center, Universitat de Barcelona, Barcelona, 
      Catalonia, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer 
      (IDIBAPS), Barcelona, Catalonia, Spain.
FAU - Valldeoriola, Francesc
AU  - Valldeoriola F
AD  - Institut de Neurociencies, Service of Neurology, Parkinson's Disease and Movement 
      Disorders Unit., Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain; 
      Institut de Neurociencies, Maeztu Center, Universitat de Barcelona, Barcelona, 
      Catalonia, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer 
      (IDIBAPS), Barcelona, Catalonia, Spain. Electronic address: fvallde@clinic.cat.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220701
PL  - United States
TA  - World Neurosurg
JT  - World neurosurgery
JID - 101528275
SB  - IM
MH  - *Deep Brain Stimulation/methods
MH  - *Dystonia/therapy
MH  - Electrodes, Implanted/adverse effects
MH  - *Essential Tremor/surgery
MH  - Humans
MH  - Software
OTO - NOTNLM
OT  - Deep brain stimulation
OT  - Dystonia
OT  - Essential tremor
OT  - Imaging
OT  - Parkinson disease
OT  - SureTune3
EDAT- 2022/07/06 06:00
MHDA- 2022/10/06 06:00
CRDT- 2022/07/05 17:56
PHST- 2022/05/07 00:00 [received]
PHST- 2022/06/24 00:00 [revised]
PHST- 2022/06/25 00:00 [accepted]
PHST- 2022/07/06 06:00 [pubmed]
PHST- 2022/10/06 06:00 [medline]
PHST- 2022/07/05 17:56 [entrez]
AID - S1878-8750(22)00916-0 [pii]
AID - 10.1016/j.wneu.2022.06.132 [doi]
PST - ppublish
SO  - World Neurosurg. 2022 Oct;166:e163-e176. doi: 10.1016/j.wneu.2022.06.132. Epub 
      2022 Jul 1.