PMID- 35790148
OWN - NLM
STAT- MEDLINE
DCOM- 20220728
LR  - 20220803
IS  - 1361-6498 (Electronic)
IS  - 0952-4746 (Linking)
VI  - 42
IP  - 3
DP  - 2022 Jul 27
TI  - Radiation exposure, organ and effective dose of CT-guided liver biopsy as a 
      function of lesion depth and size.
LID - 10.1088/1361-6498/ac7e80 [doi]
AB  - Computed tomography (CT)-guided percutaneous biopsies play an important role in 
      the diagnostic workup of liver lesions. Because radiation dose accumulates 
      rapidly due to repeated image acquisition in a relatively small scan area, 
      analysing radiation exposure is critical for improving radiation protection of 
      CT-guided interventions. The aim of this study was to assess the radiation dose 
      of CT-guided liver biopsies and the influence of lesion parameters, and to 
      establish a local diagnostic reference level (DRL). In this observational 
      retrospective cohort study, dose data of 60 CT-guided liver biopsies between 
      September 2016 and July 2017 were analysed. Radiation exposure was reported for 
      volume-weighted CT dose index (CTDI(vol)), size-specific dose estimate (SSDE), 
      dose-length product (DLP) and effective dose (ED). Radiation dose of CT-guided 
      liver biopsy was (median (interquartile range)): CTDI(vol)9.91 mGy (8.33-11.45 
      mGy), SSDE 10.42 mGy (9.39-11.70 mGy), DLP 542 mGy cm (410-733 mGy cm), ED 8.52 
      mSv (7.17-13.25 mSv). Radiation exposure was significantly higher in biopsies of 
      deep liver lesions compared to superficial lesions (DLP 679 +/- 285 mGy cm vs. 497 
      +/- 167 mGy cm,p= 0.0046). No significant dose differences were observed for 
      differences in lesion or needle size. With helical CT spirals additional to the 
      biopsy-guiding axial CT scans, radiation exposure was significantly increased: 
      797 +/- 287 mGy cm vs. 495 +/- 162 mGy cm,p< 0.0001. The local DRL is CTDI(vol)9.91 
      mGy, DLP 542 mGy cm. Radiation dose is significantly increased in biopsies of 
      deeper liver lesions compared with superficial lesions. Interventions with 
      additional biopsy-guiding CT spirals lead to higher radiation doses. This study 
      provides a detailed analysis of local radiation doses for CT-guided liver 
      biopsies and provides a benchmark for optimising radiation protection in 
      interventional radiology.
CI  - (c) 2022 Society for Radiological Protection. Published on behalf of SRP by IOP 
      Publishing Limited. All rights reserved.
FAU - Zensen, Sebastian
AU  - Zensen S
AUID- ORCID: 0000-0003-2997-0740
AD  - Institute of Diagnostic and Interventional Radiology and Neuroradiology, 
      University Hospital Essen, Hufelandstrasse 55, Essen, 45147, Germany.
FAU - Opitz, Marcel Klaus
AU  - Opitz MK
AUID- ORCID: 0000-0001-7455-8590
AD  - Institute of Diagnostic and Interventional Radiology and Neuroradiology, 
      University Hospital Essen, Hufelandstrasse 55, Essen, 45147, Germany.
FAU - Grueneisen, Johannes Stefan
AU  - Grueneisen JS
AUID- ORCID: 0000-0002-7560-8657
AD  - Institute of Diagnostic and Interventional Radiology and Neuroradiology, 
      University Hospital Essen, Hufelandstrasse 55, Essen, 45147, Germany.
FAU - Li, Yan
AU  - Li Y
AUID- ORCID: 0000-0002-3906-9481
AD  - Institute of Diagnostic and Interventional Radiology and Neuroradiology, 
      University Hospital Essen, Hufelandstrasse 55, Essen, 45147, Germany.
FAU - Haubold, Johannes
AU  - Haubold J
AUID- ORCID: 0000-0003-4843-5911
AD  - Institute of Diagnostic and Interventional Radiology and Neuroradiology, 
      University Hospital Essen, Hufelandstrasse 55, Essen, 45147, Germany.
FAU - Steinberg, Hannah Louisa
AU  - Steinberg HL
AUID- ORCID: 0000-0003-4848-4166
AD  - Institute of Diagnostic and Interventional Radiology and Neuroradiology, 
      University Hospital Essen, Hufelandstrasse 55, Essen, 45147, Germany.
FAU - Forsting, Michael
AU  - Forsting M
AD  - Institute of Diagnostic and Interventional Radiology and Neuroradiology, 
      University Hospital Essen, Hufelandstrasse 55, Essen, 45147, Germany.
FAU - Theysohn, Jens Matthias
AU  - Theysohn JM
AUID- ORCID: 0000-0001-5869-7929
AD  - Institute of Diagnostic and Interventional Radiology and Neuroradiology, 
      University Hospital Essen, Hufelandstrasse 55, Essen, 45147, Germany.
FAU - Bos, Denise
AU  - Bos D
AUID- ORCID: 0000-0002-9585-9787
AD  - Institute of Diagnostic and Interventional Radiology and Neuroradiology, 
      University Hospital Essen, Hufelandstrasse 55, Essen, 45147, Germany.
FAU - Schaarschmidt, Benedikt Michael
AU  - Schaarschmidt BM
AUID- ORCID: 0000-0001-6331-7679
AD  - Institute of Diagnostic and Interventional Radiology and Neuroradiology, 
      University Hospital Essen, Hufelandstrasse 55, Essen, 45147, Germany.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20220727
PL  - England
TA  - J Radiol Prot
JT  - Journal of radiological protection : official journal of the Society for 
      Radiological Protection
JID - 8809257
SB  - IM
MH  - Humans
MH  - Image-Guided Biopsy
MH  - *Liver Neoplasms
MH  - Radiation Dosage
MH  - *Radiation Exposure
MH  - Retrospective Studies
MH  - Tomography, X-Ray Computed/methods
OTO - NOTNLM
OT  - CT
OT  - diagnostic reference level
OT  - dosimetry
OT  - interventional radiology
OT  - liver biopsy
EDAT- 2022/07/06 06:00
MHDA- 2022/07/29 06:00
CRDT- 2022/07/05 20:18
PHST- 2022/05/18 00:00 [received]
PHST- 2022/07/05 00:00 [accepted]
PHST- 2022/07/06 06:00 [pubmed]
PHST- 2022/07/29 06:00 [medline]
PHST- 2022/07/05 20:18 [entrez]
AID - 10.1088/1361-6498/ac7e80 [doi]
PST - epublish
SO  - J Radiol Prot. 2022 Jul 27;42(3). doi: 10.1088/1361-6498/ac7e80.