PMID- 35795301
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 1178-7074 (Print)
IS  - 1178-7074 (Electronic)
IS  - 1178-7074 (Linking)
VI  - 15
DP  - 2022
TI  - Relationships Among Gut Microbiota, Ischemic Stroke and Its Risk Factors: Based 
      on Research Evidence.
PG  - 2003-2023
LID - 10.2147/IJGM.S353276 [doi]
AB  - Stroke is a highly lethal disease and disabling illness while ischemic stroke 
      accounts for the majority of stroke. It has been found that inflammation plays a 
      key role in the initiation and progression of stroke, and atherosclerotic plaque 
      rupture is considered to be the leading cause of ischemic stroke. Furthermore, 
      chronic inflammatory diseases, such as obesity, type 2 diabetes mellitus (T2DM) 
      and hypertension, are also considered as the high-risk factors for stroke. 
      Recently, the topic on how gut microbiota affects human health has aroused great 
      concern. The initiation and progression of ischemic stroke has been found to have 
      close relation with gut microbiota dysbiosis. Hence, this manuscript briefly 
      summarizes the roles of gut microbiota in ischemic stroke and its related risk 
      factors, and the practicability of preventing and alleviating ischemic stroke by 
      reconstructing gut microbiota.
CI  - (c) 2022 Huang et al.
FAU - Huang, Qinhong
AU  - Huang Q
AD  - First Clinical School, Guangzhou Medical University, Guangzhou, 511436, People's 
      Republic of China.
FAU - Cai, Guannan
AU  - Cai G
AD  - First Clinical School, Guangzhou Medical University, Guangzhou, 511436, People's 
      Republic of China.
FAU - Liu, Ting
AU  - Liu T
AD  - Guangzhou Key Laboratory of Enhanced Recovery after Abdominal Surgery, Innovation 
      Center for Advanced Interdisciplinary Medicine, the Fifth Affiliated Hospital of 
      Guangzhou Medical University, Guangzhou, 510700, People's Republic of China.
FAU - Liu, Zhihua
AU  - Liu Z
AUID- ORCID: 0000-0002-2786-3506
AD  - Department of Anorectal Surgery, the Fifth Affiliated Hospital of Guangzhou 
      Medical University, Guangzhou, 510700, People's Republic of China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220223
PL  - New Zealand
TA  - Int J Gen Med
JT  - International journal of general medicine
JID - 101515487
PMC - PMC9252587
OTO - NOTNLM
OT  - T2DM
OT  - gut microbiota
OT  - hypertension
OT  - inflammation
OT  - ischemic stroke
OT  - obesity
OT  - type 2 diabetes mellitus
COIS- The authors report no conflicts of interest in this work.
EDAT- 2022/07/08 06:00
MHDA- 2022/07/08 06:01
PMCR- 2022/02/23
CRDT- 2022/07/07 02:25
PHST- 2021/12/09 00:00 [received]
PHST- 2022/02/08 00:00 [accepted]
PHST- 2022/07/07 02:25 [entrez]
PHST- 2022/07/08 06:00 [pubmed]
PHST- 2022/07/08 06:01 [medline]
PHST- 2022/02/23 00:00 [pmc-release]
AID - 353276 [pii]
AID - 10.2147/IJGM.S353276 [doi]
PST - epublish
SO  - Int J Gen Med. 2022 Feb 23;15:2003-2023. doi: 10.2147/IJGM.S353276. eCollection 
      2022.