PMID- 35799341
OWN - NLM
STAT- MEDLINE
DCOM- 20220711
LR  - 20221116
IS  - 1942-5473 (Electronic)
IS  - 0164-1263 (Print)
IS  - 0164-1263 (Linking)
VI  - 44
IP  - 3
DP  - 2022 May 15
TI  - An Observational Retrospective Study of Adverse Events and Behavioral Outcomes 
      During Pediatric Dental Sedation.
PG  - 174-180
AB  - Purpose: The purpose of this study was to examine a university-based dental 
      electronic health records (EHR) database to identify sedation-related adverse 
      events (AEs) and assess patients' behavioral outcomes during routine pediatric 
      dental sedations (PDSs) in a dental school clinic. Methods: A database was 
      screened for patients younger than 18 years old who had received dental sedation 
      in 2019. The qualifying EHRs were then accessed and sedations were reviewed for 
      AEs, which were categorized using a 12-point classification system and the 
      Tracking and Reporting Outcomes of Procedural Sedation Tool. Patient behaviors 
      were assessed using provider progress notes and categorized as presence/ absence 
      of agitation. Results: A total of 690 sedations were reviewed, yielding 28 AEs. 
      Emesis was the most common AE observed in 1.3 percent of sedations. Respiratory 
      and cardiovascular AEs were observed in 0.7 percent and 0.6 percent of sedations, 
      respectively. Agitation was identified in 47.5 percent of sedations, while 34.1 
      percent of agitations resulted in the documented suspension of dental treatment. 
      Agitation was mainly observed for nitrous oxide and oral sedation resulting in 
      one failed sedation out of five sedations for each method. Conclusions: 
      Potentially serious adverse effects were identified during pediatric dental 
      sedations, but their incidence was low. A significant proportion of the sedated 
      children experienced agitation, resulting in some sedation failures. Such events 
      need to be tracked and examined for risk assessment reduction and quality-of-care 
      improvement.
FAU - Zouaidi, Kawtar
AU  - Zouaidi K
AD  - Dr. Zouaidi is a graduate research assistant in the Diagnostic and Biomedical 
      Sciences Department, at the School of Dentistry, University of Texas Health 
      Science Center at Houston, Houston, Texas, USA.
FAU - Olson, Gregory
AU  - Olson G
AD  - Dr. Olson is a professor and chair of the Department of Pediatric Dentistry, at 
      the School of Dentistry, University of Texas Health Science Center at Houston, 
      Houston, Texas, USA.
FAU - Lee, Helen H
AU  - Lee HH
AD  - Dr. Lee is an associate professor, Department of Anesthesiology, University of 
      Illinois at Chicago, Chicago, Ill., USA.
FAU - Kalenderian, Elsbeth
AU  - Kalenderian E
AD  - Dr. Kalenderian is a professor, School of Dentistry, University of California at 
      San Francisco, San Francisco, Calif., USA, and a senior lecturer, Harvard School 
      of Dental Medicine, Boston, Mass., USA, and an adjunct professor, School of 
      Dentistry, University of Pretoria, Pretoria, South Africa.
FAU - Walji, Muhammad F
AU  - Walji MF
AD  - Dr. Walji is a professor/associate dean for Technology Services and Informatics, 
      Diagnostic and Biomedical Sciences Department, at the School of Dentistry, 
      University of Texas Health Science Center at Houston, Houston, Texas, USA ;, 
      Email: Muhammad.f.walji@uth.tmc.edu.
LA  - eng
GR  - R01 DE022628/DE/NIDCR NIH HHS/United States
GR  - R18 HS027268/HS/AHRQ HHS/United States
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - Pediatr Dent
JT  - Pediatric dentistry
JID - 7909102
RN  - 0 (Hypnotics and Sedatives)
RN  - K50XQU1029 (Nitrous Oxide)
SB  - IM
MH  - Adolescent
MH  - Child
MH  - *Conscious Sedation/adverse effects/methods
MH  - Humans
MH  - Hypnotics and Sedatives/adverse effects
MH  - Incidence
MH  - *Nitrous Oxide/adverse effects
MH  - Retrospective Studies
PMC - PMC9648664
MID - NIHMS1787379
COIS- The authors declare that there is no conflict of interest.
EDAT- 2022/07/09 06:00
MHDA- 2022/07/12 06:00
PMCR- 2022/11/15
CRDT- 2022/07/08 00:32
PHST- 2022/07/08 00:32 [entrez]
PHST- 2022/07/09 06:00 [pubmed]
PHST- 2022/07/12 06:00 [medline]
PHST- 2022/11/15 00:00 [pmc-release]
PST - ppublish
SO  - Pediatr Dent. 2022 May 15;44(3):174-180.