PMID- 3579944
OWN - NLM
STAT- MEDLINE
DCOM- 19870611
LR  - 20190612
IS  - 0006-291X (Print)
IS  - 0006-291X (Linking)
VI  - 144
IP  - 2
DP  - 1987 Apr 29
TI  - Combined study of 1H-magnetic resonance imaging and depth-selected, EKG-gated 
      31P-magnetic resonance spectroscopy of the heart in vivo.
PG  - 841-8
AB  - NMR is useful for both 1H-magnetic resonance imaging (MRI) and magnetic resonance 
      spectroscopy (MRS). We undertook to combine these two merits of NMR for in vivo 
      characterization of living rat heart in wide bore (9 cm) superconducting magnet 
      under high magnetic field (6.4 Tesla). Spatial resolution of 1H-MRI attained 0.1 
      mm by spin warp method. Then, depth-selected, EKG-gated 31P-MRS was performed, 
      adjusting the detection area to cover the heart that was identified by the 
      preceding 1H-MRI. Three evidences that 31P-SMR signal chiefly originated from the 
      heart without cross talk of adjacent organs indicated that combination of 1H-MRI 
      and in vivo 31P-MRS under high magnetic field in whole animal is promising for 
      more accurate evaluation of cardiac muscle metabolism.
FAU - Toyo-Oka, T
AU  - Toyo-Oka T
FAU - Nagayama, K
AU  - Nagayama K
FAU - Umeda, M
AU  - Umeda M
FAU - Ogawa, S
AU  - Ogawa S
FAU - Eguchi, K
AU  - Eguchi K
FAU - Hosoda, S
AU  - Hosoda S
FAU - Sugimoto, T
AU  - Sugimoto T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Biochem Biophys Res Commun
JT  - Biochemical and biophysical research communications
JID - 0372516
RN  - 0 (Phosphates)
RN  - L628TT009W (Isoproterenol)
SB  - IM
MH  - Animals
MH  - Electrocardiography
MH  - Heart/*anatomy & histology/drug effects/physiology
MH  - Isoproterenol/pharmacology
MH  - Magnetic Resonance Spectroscopy/methods
MH  - Male
MH  - Phosphates/analysis
MH  - Rats
MH  - Rats, Inbred Strains
EDAT- 1987/04/29 00:00
MHDA- 1987/04/29 00:01
CRDT- 1987/04/29 00:00
PHST- 1987/04/29 00:00 [pubmed]
PHST- 1987/04/29 00:01 [medline]
PHST- 1987/04/29 00:00 [entrez]
AID - S0006-291X(87)80041-4 [pii]
AID - 10.1016/s0006-291x(87)80041-4 [doi]
PST - ppublish
SO  - Biochem Biophys Res Commun. 1987 Apr 29;144(2):841-8. doi: 
      10.1016/s0006-291x(87)80041-4.