PMID- 35799563 OWN - NLM STAT- MEDLINE DCOM- 20220711 LR - 20220820 IS - 0974-5181 (Electronic) IS - 0971-9784 (Print) IS - 0971-9784 (Linking) VI - 25 IP - 3 DP - 2022 Jul-Sep TI - Comparative study of cardiac output measurement by regional impedance cardiography and thermodilution method in patients undergoing off pump coronary artery bypass graft surgery. PG - 335-342 LID - 10.4103/aca.aca_44_21 [doi] AB - BACKGROUND: An ideal CO monitor should be noninvasive, cost effective, reproducible, reliable during various physiological states. Limited literature is available regarding the noninvasive CO monitoring in open chest surgeries. AIM: The aim of this study was to compare the CO measurement by Regional Impedance Cardiography (RIC) and Thermodilution (TD) method in patients undergoing off pump coronary artery bypass graft surgery (OPCAB). SETTINGS AND DESIGN: We conducted a prospective observational comparative study of CO measurement by the noninvasive RIC method using the NICaS Hemodynamic Navigator system and the gold standard TD method using pulmonary artery catheter in patients undergoing OPCAB. A total of 150 data pair from the two CO monitoring techniques were taken from 15 patients between 40-70 years at various predefined time intervals of the surgery. PATIENTS AND METHODS: We have tried to find out the accuracy, precision and cost effectiveness of the newer RIC technique. Mean CO, bias and precision were compared for each pair i.e.TD-CO and RIC-CO as recommended by Bland and Altman. The Sensitivity and specificity of cutoff value to predict change in TD-CO was used to create a Receiver operating characteristic or ROC curve. RESULTS: Mean TD-CO values were around 4.52 +/- 1.09 L/min, while mean RIC- CO values were around 4.77+/- 1.84 L/min. The difference in CO change was found to be statistically not significant (p value 0.667). The bias was small (-0.25). The Bland Altman plot revealed a mean difference of -0.25 litres. The RIC method had a sensitivity of 55.56 % and specificity of 33.33 % in predicting 15% change in CO of TD method and the total diagnostic accuracy was 46.67%. CONCLUSION: A fair correlation was found between the two techniques. The RIC method may be considered as a promising noninvasive, potentially low cost alternative to the TD technique of hemodynamic measurement. FAU - Guha, Amrita AU - Guha A AD - Department of Cardiac Anaesthesiology, Medanta the Medicity, Gurugram, Haryana, India. FAU - Arora, Dheeraj AU - Arora D AD - Department of Cardiac Anaesthesiology, Medanta the Medicity, Gurugram, Haryana, India. FAU - Mehta, Yatin AU - Mehta Y AD - Department of Cardiac Anaesthesiology, Medanta the Medicity, Gurugram, Haryana, India. LA - eng PT - Journal Article PT - Observational Study PL - India TA - Ann Card Anaesth JT - Annals of cardiac anaesthesia JID - 9815987 SB - IM MH - Cardiac Output/physiology MH - *Cardiography, Impedance/methods MH - Catheterization, Swan-Ganz MH - *Coronary Artery Bypass, Off-Pump MH - Humans MH - Reproducibility of Results MH - Thermodilution/methods PMC - PMC9387605 OTO - NOTNLM OT - Noninvasive cardiac output monitoring OT - off pump coronary artery bypass graft surgery OT - regional impedance cardiography OT - thermodilution COIS- There are no conflicts of interest. EDAT- 2022/07/09 06:00 MHDA- 2022/07/12 06:00 PMCR- 2022/07/01 CRDT- 2022/07/08 02:33 PHST- 2022/07/08 02:33 [entrez] PHST- 2022/07/09 06:00 [pubmed] PHST- 2022/07/12 06:00 [medline] PHST- 2022/07/01 00:00 [pmc-release] AID - AnnCardAnaesth_2022_25_3_335_349930 [pii] AID - ACA-25-335 [pii] AID - 10.4103/aca.aca_44_21 [doi] PST - ppublish SO - Ann Card Anaesth. 2022 Jul-Sep;25(3):335-342. doi: 10.4103/aca.aca_44_21.