PMID- 35800426
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 2322-5718 (Print)
IS  - 2322-5726 (Electronic)
IS  - 2322-5718 (Linking)
VI  - 10
IP  - 2
DP  - 2022 Spring
TI  - Challenging Results on FDG PET/CT in a Patient with Uncontrolled Celiac Disease 
      and small bowel adenocarcinoma.
PG  - 155-160
LID - 10.22038/AOJNMB.2022.61853.1437 [doi]
AB  - Celiac disease (CD) is a chronic immune-mediated enteropathy that is caused by 
      both environmental (gluten) and genetic (human leukocyte antigen (HLA) and 
      non-HLA genes) factors. Patients may be asymptomatic or exhibit atypical 
      symptoms, necessitating a high index of suspicion for proper diagnosis. The 
      evaluation of CD patients with (18)F-FDG PET/CT imaging can be difficult, owing 
      to the fact that this disease is inflammatory in nature. Typical (18)F-FDG PET/CT 
      gastrointestinal manifestations of celiac disease include increased multifocal or 
      diffuse bowel uptake, whereas single short segmental uptake is rarely 
      encountered; thus, awareness of this wide range of findings is important to guide 
      physicians through proper management and outcome. We report a case of small 
      intestine adenocarcinoma and known CD complaining of recent episodes of diarrhea 
      and weight loss that had a suspicious small bowel wall thickening that 
      corresponds to a short segmental hypermetabolic process on FDG PET/CT follow-up 
      scan. The patient was then referred to the gastroenterology department and 
      underwent a colonoscopy, a biopsy was taken that revealed CD and was negative for 
      malignancy. Furthermore, 6 months later the abovementioned segmental FDG activity 
      was completely resolved without any treatment received at the given time.
CI  - (c) 2022 mums.ac.ir All rights reserved.
FAU - Mohamedkhair, Ali
AU  - Mohamedkhair A
AD  - Department of Nuclear Medicine, King Hussein Cancer Center, Amman, Jordan.
FAU - Al-Ibraheem, Akram
AU  - Al-Ibraheem A
AD  - Department of Nuclear Medicine, King Hussein Cancer Center, Amman, Jordan.
AD  - School of Medicine, The University of Jordan, Amman, Jordan.
FAU - Saad Abdlkadir, Ahmed
AU  - Saad Abdlkadir A
AD  - Department of Nuclear Medicine, King Hussein Cancer Center, Amman, Jordan.
FAU - Jaber, Omar
AU  - Jaber O
AD  - Department of pathology, King Hussein Cancer Center, Amman, Jordan.
LA  - eng
PT  - Case Reports
PL  - Iran
TA  - Asia Ocean J Nucl Med Biol
JT  - Asia Oceania journal of nuclear medicine & biology
JID - 101611092
PMC - PMC9205848
OTO - NOTNLM
OT  - Adenocarcinoma
OT  - Celiac Disease
OT  - FDG PET/CT
OT  - Single Short Segmental Bowel Uptake
COIS- None to declare.
EDAT- 2022/07/09 06:00
MHDA- 2022/07/09 06:01
PMCR- 2022/03/01
CRDT- 2022/07/08 02:50
PHST- 2021/11/27 00:00 [received]
PHST- 2022/01/08 00:00 [revised]
PHST- 2022/01/14 00:00 [accepted]
PHST- 2022/07/08 02:50 [entrez]
PHST- 2022/07/09 06:00 [pubmed]
PHST- 2022/07/09 06:01 [medline]
PHST- 2022/03/01 00:00 [pmc-release]
AID - 10.22038/AOJNMB.2022.61853.1437 [doi]
PST - ppublish
SO  - Asia Ocean J Nucl Med Biol. 2022 Spring;10(2):155-160. doi: 
      10.22038/AOJNMB.2022.61853.1437.