PMID- 35800597
OWN - NLM
STAT- MEDLINE
DCOM- 20221223
LR  - 20221223
IS  - 0857-1074 (Print)
IS  - 2308-118X (Electronic)
IS  - 0857-1074 (Linking)
VI  - 37
IP  - 1
DP  - 2022
TI  - Medication Adherence of Persons with Type 2 Diabetes in Malaysia: A Scoping 
      Review and Meta-Analysis.
PG  - 75-82
LID - 10.15605/jafes.037.01.14 [doi]
AB  - OBJECTIVE: This is a scoping review of Malaysian scientific studies on medication 
      adherence among persons with type 2 diabetes mellitus (T2DM). METHODOLOGY: We 
      conducted a bibliographic search of PubMed, Scopus and Google Scholar using the 
      following keywords: "medication adherence," "drug compliance," "DMTAC" and 
      "Malaysia." The search covered all publications up to 31 December 2021. Eligible 
      articles were original studies conducted in Malaysia that measured or quantified 
      medication adherence among persons with T2DM. RESULTS: We identified 64 eligible 
      studies published between 2008 to 2021. Most studies included patients with T2DM 
      in ambulatory facilities. Five studies were qualitative research. The 
      quantitative research publications included clinical trials, and cross-sectional, 
      validation, retrospective and prospective cohort studies. Thirty-eight studies 
      used medication adherence scales. The Morisky Medication Adherence Scale (MMAS-8, 
      used in 20 studies) and Malaysian Medication Adherence Scale (MALMAS, used in 6 
      studies) were the most commonly used tools. There were 6 validation studies with 
      4 medication adherence scales. A meta-analysis of 10 studies using MMAS-8 or 
      MALMAS revealed that the pooled prevalence of low medication adherence is 34.2% 
      (95% CI: 27.4 to 41.2, random effects model). Eighteen publications evaluated 
      various aspects of the Diabetes Medication Therapy Adherence Clinics (DMTAC). 
      CONCLUSION: This scoping review documented extensive research on medication 
      adherence among persons with diabetes in Malaysia. The quantitative meta-analysis 
      showed a pooled low medication adherence rate.
CI  - (c) 2022 Journal of the ASEAN Federation of Endocrine Societies.
FAU - Teng, Cheong Lieng
AU  - Teng CL
AD  - Department of Family Medicine, International Medical University, Seremban Campus, 
      Negeri Sembilan, Malaysia.
FAU - Chan, Chun Wai
AU  - Chan CW
AD  - Department of Family Medicine, International Medical University, Seremban Campus, 
      Negeri Sembilan, Malaysia.
FAU - Wong, Pei Se
AU  - Wong PS
AD  - Teaching and Learning, School of Pharmacy, International Medical University, 
      Bukit Jalil, Malaysia.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
DEP - 20220430
PL  - Philippines
TA  - J ASEAN Fed Endocr Soc
JT  - Journal of the ASEAN Federation of Endocrine Societies
JID - 8608483
RN  - 0 (Hypoglycemic Agents)
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/drug therapy
MH  - Hypoglycemic Agents/therapeutic use
MH  - Malaysia
MH  - Medication Adherence
PMC - PMC9242658
OTO - NOTNLM
OT  - Malaysia
OT  - diabetes mellitus
OT  - medication adherence
OT  - scoping review
COIS- All authors certified fulfilment of ICMJE authorship criteria.
EDAT- 2022/07/09 06:00
MHDA- 2022/07/09 06:01
PMCR- 2022/01/01
CRDT- 2022/07/08 02:52
PHST- 2021/09/26 00:00 [received]
PHST- 2022/02/04 00:00 [accepted]
PHST- 2022/07/08 02:52 [entrez]
PHST- 2022/07/09 06:00 [pubmed]
PHST- 2022/07/09 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - JAFES-37-1-75 [pii]
AID - 10.15605/jafes.037.01.14 [doi]
PST - ppublish
SO  - J ASEAN Fed Endocr Soc. 2022;37(1):75-82. doi: 10.15605/jafes.037.01.14. Epub 
      2022 Apr 30.