PMID- 35805726
OWN - NLM
STAT- MEDLINE
DCOM- 20220712
LR  - 20220812
IS  - 1660-4601 (Electronic)
IS  - 1661-7827 (Print)
IS  - 1660-4601 (Linking)
VI  - 19
IP  - 13
DP  - 2022 Jun 30
TI  - Outdoor Air Pollution and Indoor Window Condensation Associated with Childhood 
      Symptoms of Allergic Rhinitis to Pollen.
LID - 10.3390/ijerph19138071 [doi]
LID - 8071
AB  - Pollen is the main factor causing asthma and allergic rhinitis (AR). However, the 
      key indoor and outdoor factors associated with childhood symptoms of allergic 
      rhinitis (SAR) to pollen are unclear. We investigate the association of exposure 
      to outdoor air pollution and indoor environmental factors with childhood SAR to 
      pollen and consider SAR to pollen in different seasons. A cross-sectional study 
      of 2598 preschool children aged 3-6 was conducted in Changsha, China (2011-2012). 
      The prevalence of SAR to pollen in children and information on indoor 
      environmental factors were obtained by questionnaire. Children's exposure to 
      outdoor air pollutants (PM(10), SO(2,) and NO(2)) was estimated from the 
      monitored concentrations. The association of exposure to indoor environmental 
      factors and outdoor air pollution with childhood SAR to pollen was estimated by 
      multiple logistic regression models using odds ratio (OR) and a 95% confidence 
      interval (CI), and the relationship between outdoor air pollutants and childhood 
      SAR to pollen was investigated using restricted cubic splines. We found that 
      early-life and current exposure to outdoor air pollution were significantly 
      associated with childhood SAR to pollen in autumn, including exposure to SO(2) 
      one year before conception (OR = 1.60, 95% CI = 1.08-2.37) and during entire 
      pregnancy (OR = 1.49, 95% CI = 1.01-2.20) periods, exposure to PM(10) during the 
      current period (OR = 1.78, 95% CI = 1.07-2.96), and exposure to NO(2) during the 
      early-life (one year before conception and entire pregnancy) and current periods 
      with ORs (95% CI) of 1.72 (1.10-2.71), 1.82 (1.17-2.83), and 1.94 (1.11-3.40), 
      respectively. Further, we found significant associations of both prenatal and 
      postnatal exposure to window condensation with childhood SAR to pollen, with ORs 
      (95% CI) = 1.37 (1.05-1.77) and 1.38 (1.02-1.88), respectively. We encourage SAR 
      to pollen sufferers to stay indoors due to outdoor air pollution and higher 
      pollen concentration outdoors, but indoor ventilation should be maintained.
FAU - Liu, Yingjie
AU  - Liu Y
AUID- ORCID: 0000-0001-6583-3669
AD  - School of Energy Science and Engineering, Central South University, Changsha 
      410083, China.
FAU - Lu, Chan
AU  - Lu C
AUID- ORCID: 0000-0002-0110-9492
AD  - XiangYa School of Public Health, Central South University, Changsha 410078, 
      China.
FAU - Li, Yuguo
AU  - Li Y
AD  - Department of Mechanical Engineering, The University of Hong Kong, Hong Kong 
      999077, China.
FAU - Norback, Dan
AU  - Norback D
AUID- ORCID: 0000-0002-5174-6668
AD  - Department of Medical Sciences, Uppsala University, 752 36 Uppsala, Sweden.
FAU - Deng, Qihong
AU  - Deng Q
AUID- ORCID: 0000-0001-9824-3534
AD  - School of Public Health, Zhengzhou University, Zhengzhou 450001, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220630
PL  - Switzerland
TA  - Int J Environ Res Public Health
JT  - International journal of environmental research and public health
JID - 101238455
RN  - 0 (Air Pollutants)
RN  - S7G510RUBH (Nitrogen Dioxide)
SB  - IM
MH  - *Air Pollutants/analysis
MH  - *Air Pollution/analysis
MH  - *Air Pollution, Indoor/analysis
MH  - Child
MH  - Child, Preschool
MH  - China/epidemiology
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Nitrogen Dioxide/analysis
MH  - Pollen
MH  - Pregnancy
MH  - *Rhinitis, Allergic/epidemiology/etiology
PMC - PMC9266097
OTO - NOTNLM
OT  - air pollution
OT  - indoor ventilation
OT  - pollen allergy
OT  - seasonal allergic rhinitis
OT  - window condensation
COIS- The authors declare no conflict of interest.
EDAT- 2022/07/10 06:00
MHDA- 2022/07/14 06:00
PMCR- 2022/06/30
CRDT- 2022/07/09 01:09
PHST- 2022/05/20 00:00 [received]
PHST- 2022/06/24 00:00 [revised]
PHST- 2022/06/25 00:00 [accepted]
PHST- 2022/07/09 01:09 [entrez]
PHST- 2022/07/10 06:00 [pubmed]
PHST- 2022/07/14 06:00 [medline]
PHST- 2022/06/30 00:00 [pmc-release]
AID - ijerph19138071 [pii]
AID - ijerph-19-08071 [pii]
AID - 10.3390/ijerph19138071 [doi]
PST - epublish
SO  - Int J Environ Res Public Health. 2022 Jun 30;19(13):8071. doi: 
      10.3390/ijerph19138071.