PMID- 35807020
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230308
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 11
IP  - 13
DP  - 2022 Jun 28
TI  - One-Year Follow-Up of Patients Admitted for Emergency Coronary Angiography after 
      Resuscitated Cardiac Arrest.
LID - 10.3390/jcm11133738 [doi]
LID - 3738
AB  - (1) Background: Despite the improvement of the in-hospital survival rate after 
      aborted sudden cardiac death (SCD), cerebral anoxia may have severe neurologic 
      consequences and may impair long-term outcome and quality of life of surviving 
      patients. The aim of this study was to assess neurological outcomes at one year 
      after resuscitated cardiac arrest; (2) Methods: This prospective, observational, 
      and multicentre study included patients >18 yo admitted in the catheterisation 
      laboratory for coronary angiography after aborted SCD between 1 May 2018 and 31 
      May 2020. Only patients who were discharged alive from hospital were evaluated. 
      The primary endpoint was survival without neurological sequelae at one-year 
      follow-up defined by a cerebral performance category (CPC) of one or two. 
      Secondary end points included all-cause mortality, New York Heart Association 
      (NYHA) functional class, neurologic evaluation at discharge, three-month and 
      one-year follow-up using the CPC scale, and quality of life at 1 year using the 
      Quality of Life after Brain Injury (QOLIBRI) questionnaire; (3) Results: Among 
      143 patients admitted for SCD within the study period, 61 (42.7%) were discharged 
      alive from hospital, among whom 55 (90.1%) completed the one-year follow-up. No 
      flow and low flow times were 1.9 +/- 2.4 min and 16.5 +/- 10.4 min, respectively. For 
      93.4% of the surviving patients, an initial shockable rhythm (n = 57) was 
      observed and acute coronary syndrome was diagnosed in 75.4% of them (n = 46). At 
      1 year, survival rate without neurologic sequelae was 87.2% (n = 48). Patients 
      with poor outcome were older (69.3 vs. 57.4 yo; p = 0.04) and had lower body mass 
      index (22.4 vs. 26.7; p = 0.013) and a lower initial Left Ventricle Ejection 
      Fraction (LVEF) (32.1% vs. 40.3%; p = 0.046). During follow-up, neurological 
      status improved in 36.8% of patients presenting sequelae at discharge, and 
      overall quality of life was satisfying for 66.7% of patients according to the 
      QOLIBRI questionnaire; (4) Conclusions: Among patients admitted to the 
      catheterisation laboratory for aborted SCD, mainly related to Acute Coronary 
      Syndrom (ACS), less than a half of them were alive at discharge. However, the 
      one-year survival rate without neurological sequelae was high and overall quality 
      of life was good.
FAU - Delbaere, Quentin
AU  - Delbaere Q
AD  - Department of Cardiology, Arnaud de Villeneuve University Hospital, 34295 
      Montpellier, France.
FAU - Akodad, Myriam
AU  - Akodad M
AD  - Department of Cardiology, Arnaud de Villeneuve University Hospital, 34295 
      Montpellier, France.
FAU - Roubille, Francois
AU  - Roubille F
AUID- ORCID: 0000-0002-5288-9687
AD  - Department of Cardiology, Arnaud de Villeneuve University Hospital, 34295 
      Montpellier, France.
FAU - Lattuca, Benoit
AU  - Lattuca B
AUID- ORCID: 0000-0001-6167-500X
AD  - Department of Cardiology, Caremeau University Hospital, 30900 Nimes, France.
FAU - Cayla, Guillaume
AU  - Cayla G
AD  - Department of Cardiology, Caremeau University Hospital, 30900 Nimes, France.
FAU - Leclercq, Florence
AU  - Leclercq F
AUID- ORCID: 0000-0001-5936-5184
AD  - Department of Cardiology, Arnaud de Villeneuve University Hospital, 34295 
      Montpellier, France.
LA  - eng
PT  - Journal Article
DEP - 20220628
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC9267145
OTO - NOTNLM
OT  - coronary angiography
OT  - neurological sequelae
OT  - quality of life
OT  - sudden cardiac death
COIS- The authors declare no conflict of interest. The funders had no role in the 
      design of the study; in the collection, analyses, or interpretation of data; in 
      the writing of the manuscript, or in the decision to publish the results.
EDAT- 2022/07/10 06:00
MHDA- 2022/07/10 06:01
PMCR- 2022/06/28
CRDT- 2022/07/09 01:16
PHST- 2022/05/17 00:00 [received]
PHST- 2022/06/15 00:00 [revised]
PHST- 2022/06/17 00:00 [accepted]
PHST- 2022/07/09 01:16 [entrez]
PHST- 2022/07/10 06:00 [pubmed]
PHST- 2022/07/10 06:01 [medline]
PHST- 2022/06/28 00:00 [pmc-release]
AID - jcm11133738 [pii]
AID - jcm-11-03738 [pii]
AID - 10.3390/jcm11133738 [doi]
PST - epublish
SO  - J Clin Med. 2022 Jun 28;11(13):3738. doi: 10.3390/jcm11133738.