PMID- 35813861
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 1687-8450 (Print)
IS  - 1687-8469 (Electronic)
IS  - 1687-8450 (Linking)
VI  - 2022
DP  - 2022
TI  - Effect of Ropivacaine Combined with Small Doses of Triamcinolone and Continuous 
      Nerve Block of Unilateral Paravertebral Canal Guided by Ultrasound on Metastasis 
      after Radical Treatment of Lung Cancer.
PG  - 6310081
LID - 10.1155/2022/6310081 [doi]
LID - 6310081
AB  - Continuous nerve block of unilateral paravertebral canal is one of the most 
      reliable and the most commonly performed techniques to control intra- and 
      postoperative pain. It is the technique of injecting local anaesthetic alongside 
      the thoracic vertebra close to where the spinal nerves emerge from the 
      intervertebral foramen. This produces unilateral, segmental, somatic, and 
      sympathetic nerve blockade, which is effective for anaesthesia and in treating 
      acute and chronic pain of unilateral origin from the chest and abdomen. 
      Ultrasound guidance with or without nerve stimulator has reduced the amount of 
      local anaesthetics (LA) to achieve a successful block, which may minimize 
      complications of continuous nerve block of unilateral paravertebral canal. 
      Previous studies have suggested that continuous nerve block of unilateral 
      paravertebral canal with ropivacaine combined with small doses of triamcinolone 
      was effective to achieve sensory and motor block after lung cancer surgery. 
      Previous studies have used a fixed large dose in different volumes and 
      concentrations for a nerve block, infraclavicular block, axillary block, and 
      humeral canal block. The results of these studies with the respects of onset 
      time, successful rate, and block duration were not consistent. Various factors, 
      including the technique used, the anatomic aspects of the injection, and the 
      pharmacodynamics aspect of drug, may influence the results. We tested the 
      hypothesis that 50,25,10 mg ropivacaine and 50,25,10 mg triamcinolone of three 
      combinations of volumes and concentrations for ultrasound-guided continuous nerve 
      block of unilateral paravertebral canal produce different effects in the aspect 
      of survival rate. Here, the drug effect was analyzed using the cross cluster 
      K-nearest neighbors (KNN). The whole experimentation was carried out under MATLAB 
      environment.
CI  - Copyright (c) 2022 Dan Xu and Wei Luo.
FAU - Xu, Dan
AU  - Xu D
AD  - Anesthesiology Department, The Second Hospital of Dalian Medical University, 
      Dalian, Liaoning, China.
FAU - Luo, Wei
AU  - Luo W
AUID- ORCID: 0000-0003-2147-7601
AD  - Anesthesiology Department, The Second Hospital of Dalian Medical University, 
      Dalian, Liaoning, China.
LA  - eng
PT  - Journal Article
DEP - 20220629
PL  - Egypt
TA  - J Oncol
JT  - Journal of oncology
JID - 101496537
PMC - PMC9259295
COIS- The authors declare no conflicts of interest.
EDAT- 2022/07/12 06:00
MHDA- 2022/07/12 06:01
PMCR- 2022/06/29
CRDT- 2022/07/11 04:07
PHST- 2022/01/14 00:00 [received]
PHST- 2022/04/04 00:00 [accepted]
PHST- 2022/07/11 04:07 [entrez]
PHST- 2022/07/12 06:00 [pubmed]
PHST- 2022/07/12 06:01 [medline]
PHST- 2022/06/29 00:00 [pmc-release]
AID - 10.1155/2022/6310081 [doi]
PST - epublish
SO  - J Oncol. 2022 Jun 29;2022:6310081. doi: 10.1155/2022/6310081. eCollection 2022.