PMID- 35815272
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220716
IS  - 1741-427X (Print)
IS  - 1741-4288 (Electronic)
IS  - 1741-427X (Linking)
VI  - 2022
DP  - 2022
TI  - Interpretation of a Quantitative Diagnosis Model of Traditional Chinese Medicine 
      Syndromes Based on Computer Adaptive Testing.
PG  - 3203158
LID - 10.1155/2022/3203158 [doi]
LID - 3203158
AB  - OBJECTIVES: The aim of this study is to interpret a quantitative diagnosis model 
      of traditional Chinese medicine (TCM) syndromes based on computer adaptive 
      testing (CAT), from the perspective of both patients and clinicians. METHODS: In 
      this cross-sectional study, patients with postprandial distress syndrome 
      completed the CAT model of TCM syndromes and the Chinese version of the Quality 
      of Life Questionnaire for Functional Digestive Disorders (Chin-FDDQL); the 
      clinicians' diagnosis was concurrently recorded. The patients completed this 
      questionnaire again after 14 +/- 2 days. The kappa test and paired chi-square test 
      were used to evaluate the consistency between the CAT model and clinical 
      diagnosis. Minimal clinically important differences (MCID) of the Chin-FDDQL 
      scores were used to assess clinical efficacy from the patients' perspective. 
      Logistic regression was used to examine the association between changes in the 
      CAT model syndrome domain scores and changes in clinical outcomes. RESULTS: 
      Changes in the CAT model syndrome domain scores may affect the clinical outcomes 
      of patients with the total scores of Chin-FDDQL (all P < 0.05). There was a 
      correlation between changes in the CAT model syndrome domain scores and the 
      patients' clinical outcomes. Different syndrome elements had different effects on 
      various Chin-FDDQL domains, which was consistent with the theory of TCM. 
      CONCLUSIONS: This study proposes a method for the clinical interpretation of the 
      CAT model of TCM syndromes, including evidence derived from the application. It 
      may provide a reference for future interpretation of other CAT models.
CI  - Copyright (c) 2022 Simeng Yao et al.
FAU - Yao, Simeng
AU  - Yao S
AUID- ORCID: 0000-0001-8282-4801
AD  - Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
FAU - Huang, Zhongyu
AU  - Huang Z
AUID- ORCID: 0000-0001-5990-2103
AD  - Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan 
      University, Guangzhou, Guangdong, China.
AD  - The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 
      Guangzhou, Guangdong, China.
AD  - Laboratory for Neuroscience in Health and Disease, Guangzhou First People's 
      Hospital, School of Medicine, South China University of Technology, Guangzhou, 
      Guangdong, China.
FAU - Liu, Xianhua
AU  - Liu X
AD  - Shenzhen Baoan Traditional Chinese Medicine Hospital Group, Shenzhen, Guangdong, 
      China.
FAU - Yan, Qiaofeng
AU  - Yan Q
AD  - No. 1 Traditional Chinese Medicine Hospital Changde, Changde, Hunan, China.
FAU - Tang, Jing
AU  - Tang J
AD  - Department of Traditional Chinese Medicine, General Hospital of the Western 
      Theater Command, Chengdu, Sichuan, China.
FAU - Liu, Fengbin
AU  - Liu F
AUID- ORCID: 0000-0003-2641-7499
AD  - The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 
      Guangzhou, Guangdong, China.
FAU - Hou, Zhengkun
AU  - Hou Z
AUID- ORCID: 0000-0001-7491-441X
AD  - The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 
      Guangzhou, Guangdong, China.
LA  - eng
PT  - Journal Article
DEP - 20220630
PL  - United States
TA  - Evid Based Complement Alternat Med
JT  - Evidence-based complementary and alternative medicine : eCAM
JID - 101215021
PMC - PMC9262526
COIS- The authors declare that there are no conflicts of interest regarding the 
      publication of this article.
EDAT- 2022/07/12 06:00
MHDA- 2022/07/12 06:01
PMCR- 2022/06/30
CRDT- 2022/07/11 04:30
PHST- 2021/07/23 00:00 [received]
PHST- 2022/03/06 00:00 [revised]
PHST- 2022/06/09 00:00 [accepted]
PHST- 2022/07/11 04:30 [entrez]
PHST- 2022/07/12 06:00 [pubmed]
PHST- 2022/07/12 06:01 [medline]
PHST- 2022/06/30 00:00 [pmc-release]
AID - 10.1155/2022/3203158 [doi]
PST - epublish
SO  - Evid Based Complement Alternat Med. 2022 Jun 30;2022:3203158. doi: 
      10.1155/2022/3203158. eCollection 2022.