PMID- 35818095
OWN - NLM
STAT- MEDLINE
DCOM- 20220713
LR  - 20220726
IS  - 2583-150X (Electronic)
IS  - 0970-258X (Linking)
VI  - 34
IP  - 6
DP  - 2021 Nov-Dec
TI  - Prevalence of obstructive sleep apnoea among patients admitted with acute 
      coronary syndrome in a hill state of northern India.
PG  - 337-340
LID - 10.25259/NMJI_413_21 [pii]
AB  - Background Obstructive sleep apnoea (OSA) is one of the emerging non-traditional 
      cardiovascular risk factors. Studying OSA may contribute towards a better 
      understanding of current concepts of atherogenesis and in guiding therapy. 
      Methods We conducted this cross-sectional study among 66 patients with acute 
      coronary syndrome (ACS) in a tertiary care hospital from 1 January 2019 to 30 
      June 2020. We included patients of ST elevation myocardial infarction (STEMI)/ 
      non-STEMI (on achieving Killip class I/II) and unstable angina and performed 
      in-hospital overnight polysomnography (PSG) within 8 weeks of index event. 
      Apnoea-hypoapnoea index (AHI) value 5-<15 was defined as mild OSA, AHI 15-<30 as 
      moderate OSA and AHI >30 as severe OSA. We analysed data using Epi Info version 
      7.2.4 for Windows. Results The 66 patients had a mean (SD) age of 57.7 (11.1) 
      years and 54 (81.8%) were men. Forty-three (65.1%) patients had STEMI, 19 (28.7%) 
      had non-STEMI and 4 (6%) had unstable angina. On PSG, the prevalence of OSA 
      (AHI>5) was 78.8% (95% CI 67.0-87.9). Of these, AHI >15 was significantly 
      associated with diabetes, hypertension and different measures of obesity 
      (p<0.05). Conclusions This study, conducted in a hill state of northern India, 
      showed a high prevalence of OSA in patients with ACS. Obesity, diabetes mellitus 
      and hypertension were significantly associated with severity of OSA (AHI>15).
FAU - Mahajan, Sanyam K
AU  - Mahajan SK
AD  - Department of Medicine, Indira Gandhi Medical College, Shimla 171001, Himachal 
      Pradesh, India.
FAU - Verma, Balbir S
AU  - Verma BS
AD  - Department of Medicine, Indira Gandhi Medical College, Shimla 171001, Himachal 
      Pradesh, India.
FAU - Sharma, Sunil
AU  - Sharma S
AD  - Department of Pulmonary Medicine, Critical Care and Sleep Medicine, Shimla 
      171001, Himachal Pradesh, India.
FAU - Mahajan, Kunal
AU  - Mahajan K
AD  - Department of Cardiology, Critical Care and Sleep Medicine, Shimla 171001, 
      Himachal Pradesh, India.
FAU - Singh, Balraj
AU  - Singh B
AD  - Department of Community Medicine, Critical Care and Sleep Medicine, Shimla 
      171001, Himachal Pradesh, India.
LA  - eng
PT  - Case Reports
PL  - India
TA  - Natl Med J India
JT  - The National medical journal of India
JID - 8809315
SB  - IM
MH  - *Acute Coronary Syndrome/complications/epidemiology
MH  - Angina, Unstable/complications/epidemiology
MH  - Cross-Sectional Studies
MH  - *Diabetes Mellitus
MH  - Female
MH  - Humans
MH  - *Hypertension
MH  - India/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Obesity
MH  - Prevalence
MH  - *Sleep Apnea, Obstructive/complications/diagnosis/epidemiology
EDAT- 2022/07/12 06:00
MHDA- 2022/07/14 06:00
CRDT- 2022/07/11 23:32
PHST- 2022/07/11 23:32 [entrez]
PHST- 2022/07/12 06:00 [pubmed]
PHST- 2022/07/14 06:00 [medline]
AID - 10.25259/NMJI_413_21 [pii]
AID - 10.25259/NMJI_413_21 [doi]
PST - ppublish
SO  - Natl Med J India. 2021 Nov-Dec;34(6):337-340. doi: 10.25259/NMJI_413_21.