PMID- 35830245 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230614 IS - 1929-0748 (Print) IS - 1929-0748 (Electronic) IS - 1929-0748 (Linking) VI - 11 IP - 7 DP - 2022 Jul 13 TI - Adapting a Motivational Interviewing Intervention to Improve HIV Prevention Among Young, Black, Sexual Minority Men in Alabama: Protocol for the Development of the Kings Digital Health Intervention. PG - e36655 LID - 10.2196/36655 [doi] LID - e36655 AB - BACKGROUND: African American or Black young men who have sex with men (BYMSM) are at a disproportionate risk for contracting HIV and have high rates of undiagnosed, and therefore untreated, HIV infection. In the southern United States, BYMSM face region-specific hurdles to HIV prevention, such as limited access to care and high levels of racism and intersectional stigma, necessitating HIV testing and pre-exposure prophylaxis interventions that address sociocultural and structural barriers while motivating BYMSM to engage in prevention. Brothers Saving Brothers (BSB) is a motivational interviewing behavioral intervention that successfully and simultaneously increased community-based HIV testing and prevention counseling and education among BYMSM in the midwestern United States. OBJECTIVE: The aim of this protocol is to detail the process for the adaption of the BSB intervention for midwestern BYMSM to the Kings intervention for southern BYMSM. During the adaptation process, the intervention will be modernized to include rapid HIV testing, as opposed to HIV testing that requires BYMSM to return for test results, pre-exposure prophylaxis, and the provision of structural supports, and for relevance in the southern United States. METHODS: Aim 1 is to gather qualitative data through focus groups and in-depth interviews with BYMSM aged 18 to 29 years in Alabama and in-depth interviews with prevention and outreach workers who routinely work with BYMSM in Alabama. NVivo qualitative software (QSR International) will be used for the coding and analysis of the transcripts via a thematic analysis approach. For aim 2, intervention mapping will guide the adaptation process, intervention content, components, and design. Both aims 1 and 2 will leverage the Exploration, Preparation, Implementation, Sustainment implementation science framework, with emphasis on the exploration and preparation phases of this model. By applying these frameworks, the original midwestern BSB intervention will be scientifically adapted to the southern BYMSM Kings intervention. RESULTS: This study is ongoing as of 2022 and is expected to conclude in 2024, with aims 1 and 2 being completed in 2023. Qualitative data will offer insight into the current real-world experiences and preferences of BYMSM in Alabama. Feedback will be collected through the adaptation process to inform intervention refinement. Institutional review board approvals have been received. CONCLUSIONS: The findings will inform next steps, that is, testing the Kings intervention for feasibility, acceptability, and preliminary effectiveness in a pilot hybrid type 1 effective-implementation randomized controlled trial. The study results will provide insights about important considerations for HIV prevention among BYMSM in the southern United States. TRIAL REGISTRATION: ClinicalTrials.gov NCT03680729; https://clinicaltrials.gov/ct2/show/NCT03680729. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/36655. CI - (c)Henna Budhwani, B Matthew Kiszla, Angulique Y Outlaw, Robert A Oster, Michael J Mugavero, Mallory O Johnson, Lisa B Hightow-Weidman, Sylvie Naar, Janet M Turan. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 13.07.2022. FAU - Budhwani, Henna AU - Budhwani H AUID- ORCID: 0000-0002-6716-9754 AD - Department of Health Policy and Organization, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, United States. FAU - Kiszla, B Matthew AU - Kiszla BM AUID- ORCID: 0000-0002-1650-0056 AD - School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States. FAU - Outlaw, Angulique Y AU - Outlaw AY AUID- ORCID: 0000-0001-5495-8693 AD - Wayne State University, Detroit, MI, United States. FAU - Oster, Robert A AU - Oster RA AUID- ORCID: 0000-0002-2247-8596 AD - School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States. FAU - Mugavero, Michael J AU - Mugavero MJ AUID- ORCID: 0000-0001-6916-6701 AD - School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States. FAU - Johnson, Mallory O AU - Johnson MO AUID- ORCID: 0000-0003-0480-2804 AD - Department of Medicine, University of California San Francisco, San Francisco, CA, United States. FAU - Hightow-Weidman, Lisa B AU - Hightow-Weidman LB AUID- ORCID: 0000-0002-2421-923X AD - University of North Carolina at Chapel Hill, Chapel Hill, NC, United States. FAU - Naar, Sylvie AU - Naar S AUID- ORCID: 0000-0001-6369-4685 AD - College of Medicine, Florida State University, Tallahassee, FL, United States. FAU - Turan, Janet M AU - Turan JM AUID- ORCID: 0000-0002-7802-6206 AD - Department of Health Policy and Organization, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, United States. LA - eng SI - ClinicalTrials.gov/NCT03680729 GR - K01 MH116737/MH/NIMH NIH HHS/United States GR - P30 MH062246/MH/NIMH NIH HHS/United States PT - Journal Article DEP - 20220713 PL - Canada TA - JMIR Res Protoc JT - JMIR research protocols JID - 101599504 PMC - PMC9330190 OTO - NOTNLM OT - African American OT - Alabama OT - HIV OT - implementation science OT - intervention OT - men who have sex with men OT - pre-exposure prophylaxis OT - sociocultural OT - structural barriers OT - youth COIS- Conflicts of Interest: None declared. EDAT- 2022/07/14 06:00 MHDA- 2022/07/14 06:01 PMCR- 2022/07/13 CRDT- 2022/07/13 11:54 PHST- 2022/01/19 00:00 [received] PHST- 2022/06/21 00:00 [accepted] PHST- 2022/05/15 00:00 [revised] PHST- 2022/07/13 11:54 [entrez] PHST- 2022/07/14 06:00 [pubmed] PHST- 2022/07/14 06:01 [medline] PHST- 2022/07/13 00:00 [pmc-release] AID - v11i7e36655 [pii] AID - 10.2196/36655 [doi] PST - epublish SO - JMIR Res Protoc. 2022 Jul 13;11(7):e36655. doi: 10.2196/36655.