PMID- 35834154
OWN - NLM
STAT- MEDLINE
DCOM- 20220804
LR  - 20220804
IS  - 1573-7403 (Electronic)
IS  - 1386-341X (Linking)
VI  - 25
IP  - 4
DP  - 2022 Aug
TI  - Predictive value of macular ganglion cell-inner plexiform layer thickness in 
      visual field defect of pituitary adenoma patients: a case-control study.
PG  - 667-672
LID - 10.1007/s11102-022-01248-6 [doi]
AB  - OBJECTIVE: The present study explored the association between preoperative 
      macular ganglion cell-inner plexiform layer thickness (GCIPL) and retinal nerve 
      fiber layer thickness (RNFL) measured by optical coherence tomography (OCT) and 
      the recovery of visual field (VF) defect after surgery in pituitary adenoma 
      patients. METHODS: This case-control study included patients with pituitary 
      adenoma in the Neurosurgery Department of Shanxi Provincial People's Hospital 
      between October 2019 and June 2021. Cranial MRI examination, three-dimensional 
      OCT, and VF testing (Humphrey Field Analyzer II750) were performed before and at 
      6months after the surgery. RESULTS: Fifty-three pituitary adenoma patients (81 
      eyes) were enrolled; 15 patients (23 eyes) were in the visual field did not 
      recover group (VFNR), and 38 patients (58 eyes) were in the visual field 
      recovered group (VFR). The temporal RNFL (P = 0.002) and average RNFL (P = 0.009) 
      in the VFNR group were significantly lower than in the VFR group. The superior 
      nasal GCIPL (P = 0.001), inferior nasal GCIPL (P = 0.001) and average GCIPL 
      (P = 0.01) were significantly lower in the VFNR group than in the VFR group (all 
      P < 0.01).The multivariable logistic regression analysis showed that nasal 
      inferior GCIPL was an independent risk factor for VF recovery (odds ratio 
      (OR) = 1.376,95% confidence interval (CI):1.089-1.739,P = 0.007). In the received 
      operating characteristics (ROC) analysis, the area under the ROC curve (AUROCs) 
      was the highest for nasal inferior GCIPL (AUROC = 0.739). CONCLUSIONS: In 
      patients who underwent resection of pituitary adenoma, nasal inferior GCIPL was 
      an independent risk factor of visual field defect recover after surgery.
CI  - (c) 2022. The Author(s), under exclusive licence to Springer Science+Business 
      Media, LLC, part of Springer Nature.
FAU - Xia, Li
AU  - Xia L
AD  - Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing 
      Ophthalmolgy and Visual Science Key Laboratory, Beijing Tongren Eye Center, 
      Capital Medical University, No.17 Hougou Lane, Chongnei Street, 100005, Beijing, 
      People's Republic of China.
AD  - Department of Ophthalmology, Shanxi Provincial People's Hospital, No.29 Twin 
      Towers, YingZe District, 030000, Taiyuan, People's Republic of China.
FAU - Wenhui, Jia
AU  - Wenhui J
AD  - Department of neurology, Shanxi Provincial People's Hospital, No.29 Twin Towers, 
      YingZe District, 030000, Taiyuan, People's Republic of China.
FAU - Xiaowen, Yang
AU  - Xiaowen Y
AD  - Infectious disease department, Shanxi Provincial People's Hospital, No.29 Twin 
      Towers, YingZe District, 030000, Taiyuan, People's Republic of China.
FAU - Wenfang, Xie
AU  - Wenfang X
AD  - Department of Ophthalmology, Shanxi Provincial People's Hospital, No.29 Twin 
      Towers, YingZe District, 030000, Taiyuan, People's Republic of China.
FAU - Wei, Zhang
AU  - Wei Z
AD  - Department of Ophthalmology, Shanxi Provincial People's Hospital, No.29 Twin 
      Towers, YingZe District, 030000, Taiyuan, People's Republic of China.
FAU - Yanjun, Hu
AU  - Yanjun H
AD  - Department of nuclear magnetic, Shanxi Provincial People's Hospital, No.29 Twin 
      Towers, YingZe District, 030000, Taiyuan, People's Republic of China.
FAU - Xiaoyan, Peng
AU  - Xiaoyan P
AD  - Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Beijing 
      Ophthalmolgy and Visual Science Key Laboratory, Beijing Tongren Eye Center, 
      Capital Medical University, No.17 Hougou Lane, Chongnei Street, 100005, Beijing, 
      People's Republic of China. Xiaoyan74000041@ccmu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20220714
PL  - United States
TA  - Pituitary
JT  - Pituitary
JID - 9814578
SB  - IM
MH  - *Adenoma/surgery
MH  - Case-Control Studies
MH  - Humans
MH  - Intraocular Pressure
MH  - Nerve Fibers
MH  - *Pituitary Neoplasms
MH  - Retinal Ganglion Cells
MH  - Tomography, Optical Coherence/methods
MH  - Vision Disorders
MH  - Visual Fields
OTO - NOTNLM
OT  - Case-control
OT  - Optical coherence tomography
OT  - Pituitary adenoma
OT  - Visual filed defect
EDAT- 2022/07/15 06:00
MHDA- 2022/08/05 06:00
CRDT- 2022/07/14 11:23
PHST- 2022/06/24 00:00 [accepted]
PHST- 2022/07/15 06:00 [pubmed]
PHST- 2022/08/05 06:00 [medline]
PHST- 2022/07/14 11:23 [entrez]
AID - 10.1007/s11102-022-01248-6 [pii]
AID - 10.1007/s11102-022-01248-6 [doi]
PST - ppublish
SO  - Pituitary. 2022 Aug;25(4):667-672. doi: 10.1007/s11102-022-01248-6. Epub 2022 Jul 
      14.