PMID- 35841128 OWN - NLM STAT- MEDLINE DCOM- 20221205 LR - 20230531 IS - 2055-5822 (Electronic) IS - 2055-5822 (Linking) VI - 9 IP - 5 DP - 2022 Oct TI - The development and initial validation of the PROMIS(R)+HF-27 and PROMIS+HF-10 profiles. PG - 3380-3392 LID - 10.1002/ehf2.14061 [doi] AB - AIMS: Heart failure (HF) is a common and morbid condition impacting multiple health domains. We previously reported the development of the PROMIS(R)-Plus-HF (PROMIS+HF) profile measure, including universal and HF-specific items. To facilitate use, we developed shorter, PROMIS+HF profiles intended for research and clinical use. METHODS AND RESULTS: Candidate items were selected based on psychometric properties and symptom range coverage. HF clinicians (n = 43) rated item importance and clinical actionability. Based on these results, we developed the PROMIS+HF-27 and PROMIS+HF-10 profiles with summary scores (0-100) for overall, physical, mental, and social health. In a cross-sectional sample (n = 600), we measured internal consistency reliability (Cronbach's alpha and Spearman-Brown), test-retest reliability (intraclass coefficient; n = 100), known-groups validity via New York Heart Association (NYHA) class, and convergent validity with Kansas City Cardiomyopathy Questionnaire (KCCQ) scores. In a longitudinal sample (n = 75), we evaluated responsiveness of baseline/follow-up scores by calculating mean differences and Cohen's d and comparing with paired t-tests. Internal consistency was good to excellent (alpha 0.82-0.94) for all PROMIS+HF-27 scores and acceptable to good (alpha/Spearman-Brown 0.60-0.85) for PROMIS+HF-10 scores. Test-retest intraclass coefficients were acceptable to excellent (0.75-0.97). Both profiles demonstrated known-groups validity for the overall and physical health summary scores based on NYHA class, and convergent validity for nearly all scores compared with KCCQ scores. In the longitudinal sample, we demonstrated responsiveness for PROMIS+HF-27 and PROMIS+HF-10 overall and physical summary scores. For the PROMIS+HF overall summary scores, a group-based increase of 7.6-8.3 points represented a small to medium change (Cohen's d = 0.40-0.42). For the PROMIS+HF physical summary scores, a group-based increase of 5.0-5.9 points represented a small to medium change (Cohen's d = 0.29-0.35). CONCLUSIONS: The PROMIS+HF-27 and PROMIS+HF-10 profiles demonstrated good psychometric characteristics with evidence of responsiveness for overall and physical health. These new measures can facilitate patient-centred research and clinical care, such as improving care quality through symptom monitoring, facilitating shared decision-making, evaluating quality of care, assessing new interventions, and monitoring during the initiation and titration of guideline-directed medical therapy. CI - (c) 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. FAU - Ahmad, Faraz S AU - Ahmad FS AUID- ORCID: 0000-0002-2613-2541 AD - Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Suite 600, Chicago, IL, 60611, USA. AD - The Center for Health Information Partnerships (CHIP), Institute of Public Health & Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. FAU - Jackson, Kathryn L AU - Jackson KL AD - Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. FAU - Yount, Susan E AU - Yount SE AD - Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. FAU - Rothrock, Nan E AU - Rothrock NE AD - Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. FAU - Kallen, Michael A AU - Kallen MA AD - Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. FAU - Lacson, Leilani AU - Lacson L AD - Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. FAU - Bilimoria, Karl Y AU - Bilimoria KY AD - Surgical Outcomes and Quality Improvement Center (SOQIC), Department of Surgery and Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. FAU - Kho, Abel N AU - Kho AN AD - The Center for Health Information Partnerships (CHIP), Institute of Public Health & Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. FAU - Mutharasan, Raja Kannan AU - Mutharasan RK AD - Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Suite 600, Chicago, IL, 60611, USA. FAU - McCullough, Peter A AU - McCullough PA AD - Truth for Health Foundation, Tucson, AZ. FAU - Bruckel, Jeffrey AU - Bruckel J AD - Division of Cardiology, University of Rochester Medical Center, Rochester, NY, USA. FAU - Fedson, Savitri AU - Fedson S AD - Section of Cardiology, Michael E DeBakey Veterans Administration Medical Center, Houston, TX, USA. AD - Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX, USA. FAU - Kimmel, Stephen E AU - Kimmel SE AD - Department of Epidemiology, University of Florida College of Public Health and Health Professions and College of Medicine, Gainesville, FL, USA. FAU - Eton, David T AU - Eton DT AD - Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA. AD - Division of Health Care Delivery Research, Mayo Clinic, Rochester, MN, USA. FAU - Grady, Kathleen L AU - Grady KL AD - Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Suite 600, Chicago, IL, 60611, USA. AD - Division of Cardiac Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. FAU - Yancy, Clyde W AU - Yancy CW AD - Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Suite 600, Chicago, IL, 60611, USA. FAU - Cella, David AU - Cella D AD - Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. AD - Center for Patient Centered Outcomes, Institute of Public Health & Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. LA - eng GR - K12 HS026385/HS/AHRQ HHS/United States GR - K23 HL155970/HL/NHLBI NIH HHS/United States GR - P30 DK092949/DK/NIDDK NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. DEP - 20220715 PL - England TA - ESC Heart Fail JT - ESC heart failure JID - 101669191 SB - IM MH - Humans MH - Reproducibility of Results MH - Surveys and Questionnaires MH - *Quality of Life MH - Cross-Sectional Studies MH - *Heart Failure/diagnosis PMC - PMC9715763 OTO - NOTNLM OT - Health status OT - Heart failure OT - Outcomes research OT - Patient-reported outcomes OT - Quality of life COIS- None declared. EDAT- 2022/07/17 06:00 MHDA- 2022/12/06 06:00 PMCR- 2022/07/15 CRDT- 2022/07/16 00:02 PHST- 2022/06/11 00:00 [revised] PHST- 2022/03/18 00:00 [received] PHST- 2022/06/27 00:00 [accepted] PHST- 2022/07/17 06:00 [pubmed] PHST- 2022/12/06 06:00 [medline] PHST- 2022/07/16 00:02 [entrez] PHST- 2022/07/15 00:00 [pmc-release] AID - EHF214061 [pii] AID - 10.1002/ehf2.14061 [doi] PST - ppublish SO - ESC Heart Fail. 2022 Oct;9(5):3380-3392. doi: 10.1002/ehf2.14061. Epub 2022 Jul 15.