PMID- 35841806 OWN - NLM STAT- MEDLINE DCOM- 20220809 LR - 20220902 IS - 1876-7753 (Electronic) IS - 1873-5061 (Linking) VI - 63 DP - 2022 Aug TI - Establishment of a human induced pluripotent stem cell line (CSUASOi010-A) by reprogramming peripheral blood mononuclear cells of a type 2 diabetic mellitus patient. PG - 102851 LID - S1873-5061(22)00200-8 [pii] LID - 10.1016/j.scr.2022.102851 [doi] AB - Type 2 diabetes mellitus (T2DM) is a major caused by insulin resistance with a relative deficiency in insulin secretion. Statistically, T2DM accounts for 90% of diabetes cases worldwide. We report the patient-specific human induced pluripotent stem cell line (iPSC) CSUASOi010-A by using Peripheral blood mononuclear cells (PBMCs) of a 62-year-old female from Type 2 diabetes mellitus (T2DM). Patient blood-derived cells were reprogrammed using the Sendai virus. CI - Copyright (c) 2022 The Authors. Published by Elsevier B.V. All rights reserved. FAU - Ding, Chengcheng AU - Ding C AD - Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China. FAU - Tan, Feng AU - Tan F AD - Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China. FAU - Zhou, Yalan AU - Zhou Y AD - Affiliated Hospital of Jining Medical College, China. FAU - Duan, Chunwen AU - Duan C AD - Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China. FAU - Gu, Jianing AU - Gu J AD - Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China. FAU - Cui, Zekai AU - Cui Z AD - Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China. FAU - Chen, Zhongping AU - Chen Z AD - Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Changsha Aier Eye Hospital, #388 Furong Middle Road, Changsha, Hunan 410015, China. FAU - Tang, Shibo AU - Tang S AD - Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China. Electronic address: tangsb@mail.sysu.edu.com. FAU - Chen, Jiansu AU - Chen J AD - Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Key Laboratory for Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China; Institute of Ophthalmology, Medical College, Jinan University, Guangzhou 510632, China. Electronic address: chenjiansu2000@163.com. LA - eng PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20220707 PL - England TA - Stem Cell Res JT - Stem cell research JID - 101316957 SB - IM MH - Cell Differentiation MH - Cell Line MH - Cellular Reprogramming MH - *Diabetes Mellitus, Type 2/metabolism MH - Female MH - Genetic Vectors MH - Humans MH - *Induced Pluripotent Stem Cells/metabolism MH - Karyotype MH - Leukocytes, Mononuclear/metabolism MH - Middle Aged EDAT- 2022/07/17 06:00 MHDA- 2022/08/10 06:00 CRDT- 2022/07/16 18:25 PHST- 2022/04/19 00:00 [received] PHST- 2022/05/27 00:00 [revised] PHST- 2022/07/01 00:00 [accepted] PHST- 2022/07/17 06:00 [pubmed] PHST- 2022/08/10 06:00 [medline] PHST- 2022/07/16 18:25 [entrez] AID - S1873-5061(22)00200-8 [pii] AID - 10.1016/j.scr.2022.102851 [doi] PST - ppublish SO - Stem Cell Res. 2022 Aug;63:102851. doi: 10.1016/j.scr.2022.102851. Epub 2022 Jul 7.