PMID- 35841863
OWN - NLM
STAT- MEDLINE
DCOM- 20220913
LR  - 20221110
IS  - 1872-6968 (Electronic)
IS  - 0303-8467 (Linking)
VI  - 220
DP  - 2022 Sep
TI  - Application of transcranial doppler in patients after stent-assisted coil 
      embolization.
PG  - 107347
LID - S0303-8467(22)00228-1 [pii]
LID - 10.1016/j.clineuro.2022.107347 [doi]
AB  - BACKGROUND AND PURPOSE: Patients with intracranial aneurysms treated with 
      stent-assisted coil embolization (SACE) require radiological and clinical 
      follow-up in view of in-stent stenosis (ISS). The aim of the study was to 
      evaluate transcranial Doppler (TCD) as an alternative to more invasive digital 
      subtraction angiography (DSA) in monitoring patients with SACE. METHODS: Over the 
      course of 72 months, from January 2016 to December 2021, we analyzed 49 patients 
      treated with SACE because of internal carotid artery (ICA) aneurysms (C6 
      ophthalmic segment or C7 communicating segment). DSA was performed in all 
      patients at 24-months and TCD was examined preoperatively and at 3, 6, 12, and 
      24-months postoperatively. The degree of stenosis found on TCD was compared with 
      the results of DSA. Preoperative and postoperative blood flow velocities, 
      including peak systolic blood flow velocity (Vs), end diastolic velocity (Vd), 
      and mean velocity (Vm), were compared and the optimal cutoff velocities for 
      detecting stenosis were calculated. RESULTS: Pre-embolization middle cerebral 
      artery (MCA) and intracranial terminal internal cerebral arteries (TICA) 
      velocities and pulsatility index (PI) did not significantly differ between the 
      ipsilateral and contralateral sides. The blood flow velocities, Vs, Vd, and Vm, 
      on the operation side significantly increased after SACE (P < 0.05). Over the 
      24-month study period, 7 of the 49 patients (14.3%) exhibited angiographic ISS. 
      ISS of TCD and DSA results at 24-months were compared and found to correlate 
      well; the Cohen's kappa coefficient was 0.851 (95% CI 0.651-1.051). The optimal 
      cutoff velocity for detecting ISS was MCA Vs = 173.5 cm/s. CONCLUSIONS: TCD is a 
      potentially useful adjunct for evaluating ISS after SACE.
CI  - Copyright (c) 2022 The Authors. Published by Elsevier B.V. All rights reserved.
FAU - Shi, Xin
AU  - Shi X
AD  - The Second Hospital of Hebei Medical University, Hebei, China.
FAU - Huang, Jing
AU  - Huang J
AD  - The Second Hospital of Hebei Medical University, Hebei, China.
FAU - Su, Xudong
AU  - Su X
AD  - The Second Hospital of Hebei Medical University, Hebei, China.
FAU - Chang, Xiangyang
AU  - Chang X
AD  - The Second Hospital of Hebei Medical University, Hebei, China.
FAU - Dang, Zhimin
AU  - Dang Z
AD  - The Second Hospital of Hebei Medical University, Hebei, China.
FAU - Yang, Guofeng
AU  - Yang G
AD  - The Second Hospital of Hebei Medical University, Hebei, China. Electronic 
      address: guilaidingding@sina.com.
LA  - eng
PT  - Journal Article
DEP - 20220621
PL  - Netherlands
TA  - Clin Neurol Neurosurg
JT  - Clinical neurology and neurosurgery
JID - 7502039
SB  - IM
MH  - Blood Flow Velocity
MH  - Constriction, Pathologic
MH  - Humans
MH  - *Middle Cerebral Artery/diagnostic imaging/surgery
MH  - Stents
MH  - *Ultrasonography, Doppler, Transcranial
OTO - NOTNLM
OT  - Aneurysms
OT  - In-stent stenosis
OT  - Stent-assisted coil embolization
OT  - Transcranial Doppler
EDAT- 2022/07/17 06:00
MHDA- 2022/09/14 06:00
CRDT- 2022/07/16 18:31
PHST- 2022/04/19 00:00 [received]
PHST- 2022/06/07 00:00 [revised]
PHST- 2022/06/19 00:00 [accepted]
PHST- 2022/07/17 06:00 [pubmed]
PHST- 2022/09/14 06:00 [medline]
PHST- 2022/07/16 18:31 [entrez]
AID - S0303-8467(22)00228-1 [pii]
AID - 10.1016/j.clineuro.2022.107347 [doi]
PST - ppublish
SO  - Clin Neurol Neurosurg. 2022 Sep;220:107347. doi: 10.1016/j.clineuro.2022.107347. 
      Epub 2022 Jun 21.