PMID- 3584231
OWN - NLM
STAT- MEDLINE
DCOM- 19870720
LR  - 20161026
IS  - 0021-9509 (Print)
IS  - 0021-9509 (Linking)
VI  - 28
IP  - 3
DP  - 1987 May-Jun
TI  - Seventy-six month experience with the Omniscience cardiac valve.
PG  - 328-32
AB  - Between August 1978 and September 1984, 440 patients were implanted with the 
      Omniscience cardiac valve at three North American medical centers (210 aortic, 
      AVR; 165 mitral, MVR; and 65 double valve replacements). Total follow-up was 1056 
      patient years; survivors were followed up to 76 months (mean 32), with 99% 
      accountability. One hundred and eighty-six (42%) also underwent prior or 
      concomitant major cardiac surgical procedures. Mean age was 56 +/- 12 years. 
      Preoperatively, 3% were in New York Heart Association (NYHA) Class I, 18% II, 54% 
      III, 26% IV. The 5 1/2 year actuarial survival rate for death from valve-related 
      causes (thromboembolism, valve thrombosis, perivalvular leak) was 97% overall. 
      The 5 1/2 year actuarial survival rate from all death causes was 78%. The 
      complication rates, expressed as %/patient-year (endocarditis 0.7; 
      anticoagulant-related hemorrhage 1.0; perivalvular leak 1.5; pannus/tissue 
      overgrowth 0.6; and transient ischemic episode 1.2) demonstrate that advanced age 
      at implant and additional major cardiac surgical procedures do not affect 
      occurrence. Actuarial freedom from thrombotic complications (thromboembolism with 
      residual deficit and valve thrombosis) at 5 1/2 years was 95% overall. 
      Postoperatively, of 348 patients with known NYHA, 65% were in NYHA I, 28% II, 5% 
      III, and 2% IV.
FAU - DeWall, R A
AU  - DeWall RA
FAU - Schuster, B
AU  - Schuster B
FAU - Hicks, G Jr
AU  - Hicks G Jr
FAU - Pelletier, C
AU  - Pelletier C
FAU - Bonan, R
AU  - Bonan R
FAU - Martineau, J P
AU  - Martineau JP
FAU - Panebianco, A
AU  - Panebianco A
FAU - Yip, L
AU  - Yip L
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - J Cardiovasc Surg (Torino)
JT  - The Journal of cardiovascular surgery
JID - 0066127
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aortic Valve/surgery
MH  - Equipment Failure
MH  - Female
MH  - Heart Valve Diseases/*surgery
MH  - *Heart Valve Prosthesis/mortality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve/surgery
MH  - Postoperative Complications
MH  - Thromboembolism/etiology
EDAT- 1987/05/01 00:00
MHDA- 2001/03/28 10:01
CRDT- 1987/05/01 00:00
PHST- 1987/05/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1987/05/01 00:00 [entrez]
PST - ppublish
SO  - J Cardiovasc Surg (Torino). 1987 May-Jun;28(3):328-32.