PMID- 35845024 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220719 IS - 2364-3722 (Print) IS - 2196-9736 (Electronic) IS - 2196-9736 (Linking) VI - 10 IP - 7 DP - 2022 Jul TI - Bowel preparation prior to colonoscopy with a new colonic irrigation device: Results of a prospective observational study. PG - E971-E977 LID - 10.1055/a-1858-3728 [doi] AB - Background and study aims The success of colonoscopy is mainly dependent on the effectiveness of prior bowel preparation (BP). Patients often consider BP to be the most burdensome part of colonoscopy, which might be a main barrier to the procedure. The aim of this study was to evaluate safety and effectiveness of colonic irrigation with a new colon hydrotherapy (CHT) device as an alternative to traditional oral BP. Patients and methods A prospective, non-randomized observational study was conducted to evaluate the quality of BP. A BP was considered effective if a score of 6 or better through the Boston Bowel Preparation Scale (BBPS) could be reached. Colonoscopy was performed immediately following colonic irrigation. For safety analysis, data on adverse events (AEs) were collected. Among the secondary outcomes, the BBPS assessed in each bowel segment and cecal intubation rate were analyzed. Results Twenty-eight consecutive patients (11 male [39.3%] and 17 [60.7 %] female) undergoing screening/surveillance or diagnostic colonoscopy were enrolled. Mean age was 54 +/- 12.4 years (range 19-80). The evaluated mean BBPS was 7.8 +/- 1.5. Twenty-five patients (89.3 %) had a BBPS score of 6 or above. Colonic irrigation was performed without any complications and no AEs were reported within 30 days. The cecal intubation rate was 100 %. Conclusions Colonic irrigation with a new CHT device is an effective and low-risk alternative to traditional oral preparation prior to colonoscopy. CI - The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). FAU - Teich, Niels AU - Teich N AD - Internistische Gemeinschaftspraxis fur Verdauungs- und Stoffwechselkrankheiten, Leipzig und Schkeuditz, Germany. FAU - Klecker, Chris AU - Klecker C AD - Internistische Gemeinschaftspraxis fur Verdauungs- und Stoffwechselkrankheiten, Leipzig und Schkeuditz, Germany. FAU - Klugmann, Tobias AU - Klugmann T AD - Internistische Gemeinschaftspraxis fur Verdauungs- und Stoffwechselkrankheiten, Leipzig und Schkeuditz, Germany. FAU - Dietel, Peter AU - Dietel P AD - Internistische Gemeinschaftspraxis fur Verdauungs- und Stoffwechselkrankheiten, Leipzig und Schkeuditz, Germany. LA - eng PT - Journal Article DEP - 20220715 PL - Germany TA - Endosc Int Open JT - Endoscopy international open JID - 101639919 PMC - PMC9286771 COIS- Competing interests The authors received financial remuneration for all study procedures in accordance with the German tariff for doctors (GOA) by Herrmann Apparatebau GmbH, Germany. EDAT- 2022/07/19 06:00 MHDA- 2022/07/19 06:01 PMCR- 2022/07/01 CRDT- 2022/07/18 03:44 PHST- 2021/11/04 00:00 [received] PHST- 2022/05/03 00:00 [accepted] PHST- 2022/07/18 03:44 [entrez] PHST- 2022/07/19 06:00 [pubmed] PHST- 2022/07/19 06:01 [medline] PHST- 2022/07/01 00:00 [pmc-release] AID - 10.1055/a-1858-3728 [doi] PST - epublish SO - Endosc Int Open. 2022 Jul 15;10(7):E971-E977. doi: 10.1055/a-1858-3728. eCollection 2022 Jul.