PMID- 35847191
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220719
IS  - 2214-6873 (Print)
IS  - 2214-6873 (Electronic)
IS  - 2214-6873 (Linking)
VI  - 29
DP  - 2022 Jul
TI  - Combined use of beta-tricalcium phosphate with different porosities can 
      accelerate bone remodelling in open-wedge high tibial osteotomy.
PG  - 30-34
LID - 10.1016/j.asmart.2022.05.004 [doi]
AB  - BACKGROUND/OBJECTIVE: Beta-tricalcium phosphate (beta-TCP) is often used as a gap 
      filler in open-wedge high tibial osteotomy (OWHTO). The aim of the present study 
      was to investigate the effects of using beta-TCP with different porosities on bone 
      remodelling after OWHTO.Methods: We evaluated 29 knees in 26 patients that 
      underwent OWHTO using beta-TCP with porosities of 60% and 75% (combined group). A 
      further 30 knees in 28 patients that underwent OWHTO using beta-TCP with 60% 
      porosity alone were allocated as a control group. In the combined group, a beta-TCP 
      block with 75% porosity was inserted into the gap at the cancellous bone site and 
      a beta-TCP block with 60% porosity was inserted into the medial cortical bone side. 
      In the control group, a beta-TCP block with 60% porosity was inserted into the 
      osteotomy gap. The bone remodelling phases of the inserted beta-TCP blocks were 
      evaluated on standard anteroposterior radiographs using the modified van Hemert 
      classification at 3 and 6 months post-operatively. RESULTS: The rate of 
      satisfactory bone remodelling at the cancellous bone sites was 86.2% (25/29) in 
      the combined group and 0% (0/30) in the control group at 3 months 
      post-operatively (p<0.05), progressing to 96.6% (28/29) in the combined group and 
      20% (6/30) in the control group at 6 months post-operatively (p<0.05). 
      CONCLUSION: The present study demonstrated that combined use of beta-TCP with high 
      and low porosities can significantly enhance bone formation. The combined use of 
      artificial bones with different porosities is useful for early bone remodelling 
      in OWHTO.
CI  - (c) 2022 Asia Pacific Knee, Arthroscopy and Sports Medicine Society. Published by 
      Elsevier (Singapore) Pte Ltd.
FAU - Sasaki, Sota
AU  - Sasaki S
AD  - Department of Orthopaedic Surgery, Fukuoka University Faculty of Medicine, 7-45-1 
      Nanakuma, Jonan-ku, Fukuoka, 810-0180, Japan.
FAU - Maeyama, Akira
AU  - Maeyama A
AD  - Department of Orthopaedic Surgery, Fukuoka University Faculty of Medicine, 7-45-1 
      Nanakuma, Jonan-ku, Fukuoka, 810-0180, Japan.
FAU - Kiyama, Takahiko
AU  - Kiyama T
AD  - Department of Orthopaedic Surgery, Fukuoka University Faculty of Medicine, 7-45-1 
      Nanakuma, Jonan-ku, Fukuoka, 810-0180, Japan.
FAU - Kamada, Satoshi
AU  - Kamada S
AD  - Department of Rehabilitation, Fukuoka University Faculty of Medicine, 7-45-1 
      Nanakuma, Jonan-ku, Fukuoka, 810-0180, Japan.
FAU - Kobayashi, Tomohiro
AU  - Kobayashi T
AD  - Department of Orthopaedic Surgery, Fukuoka University Faculty of Medicine, 7-45-1 
      Nanakuma, Jonan-ku, Fukuoka, 810-0180, Japan.
FAU - Ishii, Satohiro
AU  - Ishii S
AD  - Department of Orthopaedic Surgery, Fukuoka University Faculty of Medicine, 7-45-1 
      Nanakuma, Jonan-ku, Fukuoka, 810-0180, Japan.
FAU - Yamamoto, Takuaki
AU  - Yamamoto T
AD  - Department of Orthopaedic Surgery, Fukuoka University Faculty of Medicine, 7-45-1 
      Nanakuma, Jonan-ku, Fukuoka, 810-0180, Japan.
LA  - eng
PT  - Journal Article
DEP - 20220705
PL  - Singapore
TA  - Asia Pac J Sports Med Arthrosc Rehabil Technol
JT  - Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and 
      technology
JID - 101648546
PMC - PMC9262697
OTO - NOTNLM
OT  - Beta-tricalcium phosphate
OT  - Bone remodelling
OT  - OWHTO, Medial open-wedge high tibial osteotomy
OT  - Osteotomy
OT  - Porosity
OT  - beta-TCP, beta-tricalcium phosphate
COIS- A conflict of interest occurs when an individual's objectivity is potentially 
      compromised by a desire for financial gain, prominence, professional advancement 
      or a successful outcome. AP-SMART Editors strive to ensure that what is published 
      in the Journal is as balanced, objective and evidence-based as possible. Since it 
      can be difficult to distin-guish between an actual conflict of interest and a 
      perceived conflict of interest, the Journal requires authors to dis-close all and 
      any potential conflicts of interest.
EDAT- 2022/07/19 06:00
MHDA- 2022/07/19 06:01
PMCR- 2022/07/05
CRDT- 2022/07/18 04:12
PHST- 2022/01/10 00:00 [received]
PHST- 2022/04/22 00:00 [revised]
PHST- 2022/05/24 00:00 [accepted]
PHST- 2022/07/18 04:12 [entrez]
PHST- 2022/07/19 06:00 [pubmed]
PHST- 2022/07/19 06:01 [medline]
PHST- 2022/07/05 00:00 [pmc-release]
AID - S2214-6873(22)00014-0 [pii]
AID - 10.1016/j.asmart.2022.05.004 [doi]
PST - epublish
SO  - Asia Pac J Sports Med Arthrosc Rehabil Technol. 2022 Jul 5;29:30-34. doi: 
      10.1016/j.asmart.2022.05.004. eCollection 2022 Jul.