PMID- 35854437
OWN - NLM
STAT- MEDLINE
DCOM- 20230524
LR  - 20230524
IS  - 1940-1574 (Electronic)
IS  - 0003-3197 (Linking)
VI  - 74
IP  - 6
DP  - 2023 Jul
TI  - Impact of Stress Hyperglycemia on the Timing of Complete Revascularization in 
      Non-diabetes Patients with ST Elevation Myocardial Infarction and Multivessel 
      Disease.
PG  - 587-595
LID - 10.1177/00033197221115555 [doi]
AB  - Background: Stress hyperglycemia (SHG) is related to an increased risk of 
      mortality in diabetic patients with ST elevation myocardial infarction (STEMI) 
      undergoing primary percutaneous coronary intervention (PPCI). However, data are 
      limited in non-diabetic patients especially in patients with multivessel disease 
      (MVD). Methods and Results: In this retrospective study, 742 non-diabetic 
      patients with STEMI and MVD were divided into SHG group and non-SHG group. The 
      overall incidence of SHG was 24.9%. The incidence of no-reflow (NR) phenomenon 
      (18.4% vs 11.8%; P = .024) and in-hospital mortality (1.6% vs .2%; P = .020) in 
      SHG group were significantly higher than those in non-SHG group. SHG was 
      associated with 30-day MACE (hazard ratio, 4.265; 95% confidence interval (CI), 
      1.354-13.439; P = .013), but not 1-year. Multivariate logistic analysis showed 
      that SHG (odds ratio: 1.691, 95% CI: 1.072-2.667, P = .024) was an independent 
      predictor of NR. If complete revascularization (CR) was performed during PPCI, 
      the incidence of NR would be significantly higher. Conclusion: In non-diabetic 
      patients with STEMI and MVD, SHG is associated with increased SF-NR and 
      short-term adverse events, and CR during PPCI further increases the risk of NR.
FAU - Zheng, Wen
AU  - Zheng W
AD  - Department of Cardiology Beijing Anzhen Hospital, Capital Medical University, 
      Beijing, China.
FAU - Huang, Xin
AU  - Huang X
AUID- ORCID: 0000-0002-1248-9996
AD  - Department of Cardiology, Beijing Shijitan Hospital, Capital Medical University, 
      Beijing, China.
FAU - Zhao, Xuedong
AU  - Zhao X
AD  - Department of Cardiology Beijing Anzhen Hospital, Capital Medical University, 
      Beijing, China.
FAU - Gong, Wei
AU  - Gong W
AD  - Department of Cardiology Beijing Anzhen Hospital, Capital Medical University, 
      Beijing, China.
FAU - Wang, Xiao
AU  - Wang X
AD  - Department of Cardiology Beijing Anzhen Hospital, Capital Medical University, 
      Beijing, China.
FAU - Nie, Shaoping
AU  - Nie S
AD  - Department of Cardiology Beijing Anzhen Hospital, Capital Medical University, 
      Beijing, China.
LA  - eng
PT  - Journal Article
DEP - 20220719
PL  - United States
TA  - Angiology
JT  - Angiology
JID - 0203706
SB  - IM
CIN - Angiology. 2023 Jul;74(6):596-597. PMID: 36165396
MH  - Humans
MH  - *ST Elevation Myocardial Infarction/surgery/complications
MH  - *Coronary Artery Disease
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Treatment Outcome
MH  - *Percutaneous Coronary Intervention/adverse effects
MH  - *Diabetes Mellitus/epidemiology
MH  - *Hyperglycemia/complications
MH  - Myocardial Revascularization/adverse effects
OTO - NOTNLM
OT  - ST segment elevation myocardial infarction
OT  - complete revascularization
OT  - multivessel coronary artery disease
OT  - no-reflow
OT  - stress hyperglycemia
EDAT- 2022/07/21 06:00
MHDA- 2023/05/24 06:42
CRDT- 2022/07/20 00:42
PHST- 2023/05/24 06:42 [medline]
PHST- 2022/07/21 06:00 [pubmed]
PHST- 2022/07/20 00:42 [entrez]
AID - 10.1177/00033197221115555 [doi]
PST - ppublish
SO  - Angiology. 2023 Jul;74(6):587-595. doi: 10.1177/00033197221115555. Epub 2022 Jul 
      19.