PMID- 35858014
OWN - NLM
STAT- MEDLINE
DCOM- 20221111
LR  - 20221207
IS  - 1806-9460 (Electronic)
IS  - 1516-3180 (Print)
IS  - 1516-3180 (Linking)
VI  - 140
IP  - 6
DP  - 2022 Nov-Dec
TI  - Association between glycemic control and albuminuria among Peruvian adults with 
      diabetes mellitus 2: a cross-sectional analytical study.
PG  - 767-774
LID - 10.1590/1516-3180.2021.0448.R2.07022022 [doi]
AB  - BACKGROUND: Albuminuria is a risk factor for microvascular and macrovascular 
      complications in the diabetic population. However, few studies have correlated 
      poor glycemic control and albuminuria prevalence in Hispanic populations. 
      OBJECTIVE: To evaluate the association between glycemic control and albuminuria 
      among Peruvian adults with type 2 diabetes mellitus (T2DM). DESIGN AND SETTING: 
      Cross-sectional analytical study among adults with T2DM in Lima, Peru. METHODS: 
      We included adults over 18 years old who were in a clinical follow-up program at 
      a private clinic in Lima in 2018. Poor glycemic control was defined as a serum 
      value of glycosylated hemoglobin A1C (HbA1C) >/= 7%. Albuminuria was defined as 
      albumin values > 30 mg/dl in the first morning urine. We generated generalized 
      linear regression models from the Poisson family with robust variance. We 
      calculated the crude and adjusted prevalence ratios (PRs) with their 95% 
      confidence interval (CI). RESULTS: We analyzed 907 participants of median age 58 
      years (interquartile range, IQR 49 to 66), and 62.8% were males. The prevalence 
      of poor glycemic control was 39.8%, and the prevalence of albuminuria was 22.7%. 
      The prevalences of albuminuria in groups with poor glycemic control and adequate 
      glycemic control were 32.7% and 16.1%, respectively. In the adjusted regression 
      analysis, we found a statistically significant association between poor glycemic 
      control and albuminuria (annual percentage rate, aPR = 1.70; 95% CI: 1.28-2.27). 
      CONCLUSIONS: The prevalence of poor glycemic control and albuminuria was high in 
      our study population. Moreover, Peruvian T2DM adults with poor glycemic control 
      were more likely to have albuminuria.
FAU - Collazos-Huaman, Lucero Del Carmen
AU  - Collazos-Huaman LDC
AUID- ORCID: 0000-0002-9314-1181
AD  - Undergraduate Student, Faculty of Medicine, Universidad Peruana de Ciencias 
      Aplicadas (UPC), Lima, Peru.
FAU - Guerreros-Espino, Camila
AU  - Guerreros-Espino C
AUID- ORCID: 0000-0002-3170-2254
AD  - Undergraduate Student, Faculty of Medicine, Universidad Peruana de Ciencias 
      Aplicadas (UPC), Lima, Peru.
FAU - Herrera-Anazco, Percy
AU  - Herrera-Anazco P
AUID- ORCID: 0000-0003-0282-6634
AD  - MD, MHEd. Researcher, Universidad Privada San Juan Bautista (UPSJB), Lima, Peru; 
      and Assistant Manager, EsSalud, Instituto de Evaluacion de Tecnologias en Salud e 
      Investigacion, Lima, Peru.
FAU - Benites-Zapata, Vicente Aleixandre
AU  - Benites-Zapata VA
AUID- ORCID: 0000-0002-9158-1108
AD  - MD. Researcher, Unidad para la Generacion y Sintesis de Evidencias en Salud, 
      Universidad San Ignacio de Loyola (USIL), Lima, Peru.
LA  - eng
PT  - Journal Article
PL  - Brazil
TA  - Sao Paulo Med J
JT  - Sao Paulo medical journal = Revista paulista de medicina
JID - 100897261
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adult
MH  - Male
MH  - Humans
MH  - Middle Aged
MH  - Adolescent
MH  - Female
MH  - *Albuminuria/complications/epidemiology
MH  - *Diabetes Mellitus, Type 2/complications/epidemiology
MH  - Peru/epidemiology
MH  - Glycemic Control
MH  - Cross-Sectional Studies
MH  - Glycated Hemoglobin/analysis
MH  - Blood Glucose
PMC - PMC9671563
COIS- Conflict of interest: The authors declare that they did not have any conflicts of 
      interest
EDAT- 2022/07/21 06:00
MHDA- 2022/11/15 06:00
PMCR- 2022/07/15
CRDT- 2022/07/20 15:14
PHST- 2021/05/25 00:00 [received]
PHST- 2022/02/07 00:00 [accepted]
PHST- 2022/07/21 06:00 [pubmed]
PHST- 2022/11/15 06:00 [medline]
PHST- 2022/07/20 15:14 [entrez]
PHST- 2022/07/15 00:00 [pmc-release]
AID - S1516-31802022005017201 [pii]
AID - 10.1590/1516-3180.2021.0448.R2.07022022 [doi]
PST - ppublish
SO  - Sao Paulo Med J. 2022 Nov-Dec;140(6):767-774. doi: 
      10.1590/1516-3180.2021.0448.R2.07022022.