PMID- 35858498 OWN - NLM STAT- MEDLINE DCOM- 20221020 LR - 20230119 IS - 2211-0356 (Electronic) IS - 2211-0348 (Print) IS - 2211-0348 (Linking) VI - 66 DP - 2022 Oct TI - Fulminant neuromyelitis optica spectrum disorder (NMOSD) following COVID-19 vaccination: A need for reconsideration? PG - 104035 LID - S2211-0348(22)00543-0 [pii] LID - 10.1016/j.msard.2022.104035 [doi] AB - During the coronavirus disease 2019 (COVID-19) pandemic, mass vaccination was a beneficial strategy in many countries. Nevertheless, reports of serious complications such as postvaccination neuromyelitis optica spectrum disorder (NMOSD) raised concerns about the safety of vaccines. Anamnart and colleagues explained postvaccination NMOSD following different vaccines, including COVID-19. To emphasize the message of this article, in this letter, we present a unique case of postvaccination NMOSD with a fulminant and fatal course, which may show a plausible relationship between COVID-19 vaccination and triggering anti-aquaporin-4 antibody (AQP4-Ab). CI - Copyright (c) 2022. Published by Elsevier B.V. FAU - Motahharynia, Ali AU - Motahharynia A AD - Center for Translational Neuroscience, Isfahan University of Medical Sciences, Isfahan, Iran; Isfahan Neuroscience Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. FAU - Naghavi, Saba AU - Naghavi S AD - Center for Translational Neuroscience, Isfahan University of Medical Sciences, Isfahan, Iran; Isfahan Neuroscience Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. FAU - Shaygannejad, Vahid AU - Shaygannejad V AD - Center for Translational Neuroscience, Isfahan University of Medical Sciences, Isfahan, Iran; Isfahan Neuroscience Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. FAU - Adibi, Iman AU - Adibi I AD - Center for Translational Neuroscience, Isfahan University of Medical Sciences, Isfahan, Iran; Isfahan Neuroscience Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: i_adibi@med.mui.ac.ir. LA - eng PT - Case Reports PT - Letter DEP - 20220705 PL - Netherlands TA - Mult Scler Relat Disord JT - Multiple sclerosis and related disorders JID - 101580247 RN - 0 (anti-aquaporin 4 autoantibody) RN - 0 (Aquaporin 4) RN - 0 (Autoantibodies) RN - 0 (COVID-19 Vaccines) SB - IM CIN - Mult Scler Relat Disord. 2022 Dec;68:104089. PMID: 35987109 MH - Humans MH - Aquaporin 4 MH - Autoantibodies MH - *COVID-19/prevention & control MH - *COVID-19 Vaccines/adverse effects MH - *Neuromyelitis Optica/complications MH - Vaccination/adverse effects PMC - PMC9254455 OTO - NOTNLM OT - COVID-19 vaccine OT - NMOSD OT - Neuromyelitis optica spectrum disorder OT - Postvaccination COIS- Declaration of Interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2022/07/21 06:00 MHDA- 2022/10/20 06:00 PMCR- 2022/07/05 CRDT- 2022/07/20 18:13 PHST- 2022/04/26 00:00 [received] PHST- 2022/07/04 00:00 [accepted] PHST- 2022/07/21 06:00 [pubmed] PHST- 2022/10/20 06:00 [medline] PHST- 2022/07/20 18:13 [entrez] PHST- 2022/07/05 00:00 [pmc-release] AID - S2211-0348(22)00543-0 [pii] AID - 104035 [pii] AID - 10.1016/j.msard.2022.104035 [doi] PST - ppublish SO - Mult Scler Relat Disord. 2022 Oct;66:104035. doi: 10.1016/j.msard.2022.104035. Epub 2022 Jul 5.