PMID- 35863643 OWN - NLM STAT- MEDLINE DCOM- 20221005 LR - 20221214 IS - 1878-8769 (Electronic) IS - 1878-8750 (Linking) VI - 166 DP - 2022 Oct TI - Does Preoperative Symptom Duration Impact Clinical Outcomes After Minimally Invasive Transforaminal Lumbar Interbody Fusion in the Ambulatory Setting? PG - e599-e606 LID - S1878-8750(22)01004-X [pii] LID - 10.1016/j.wneu.2022.07.055 [doi] AB - BACKGROUND: The effect of prolonged symptom duration in patients undergoing ambulatory MIS-TLIF on postoperative clinical outcomes has not been well studied. We aim to compare symptom duration of pain and/or weakness on postoperative outcomes in patients undergoing outpatient MIS-TLIF. METHODS: Patients undergoing outpatient MIS-TLIF were gathered in a single-surgeon database. Exclusion criteria were patients missing onset of symptoms, date of surgery, or diagnosis of malignancy, trauma, or infection. Patients were grouped by symptoms <1 year or symptoms >/=1 year. Propensity score matching for demographics was utilized. Minimal clinically important difference (MCID) achievement was calculated by comparing change in patient-reported outcome measures (PROMs) to previously established values. Inferential statistics for demographics, perioperative characteristics, PROMs, and MCID were utilized to compare between groups and/or postoperative improvement. RESULTS: After matching, there were a total of 56 patients, with 30 patients with symptoms <1-year. The <1-year cohort reported significant improvement in all time points in VAS back/leg and 12-week/6-months in ODI. The >/=1-year cohort demonstrated significant improvement in 6-month Patient-Reported Outcomes Measurement-Information System Physical Function, 6-week to 1-year VAS back, 6-week VAS leg, and 6-month ODI. The <1-year cohort had higher MCID attainment rates in 1-year VAS back/leg. CONCLUSIONS: Independent of symptom duration, patients reported significant improvement in back pain at all postoperative periods. Patients presenting with shorter symptom duration consistently reported significant improvement in leg pain postoperatively. Patients with shorter symptom duration demonstrated greater MCID achievement in back and leg pain. Patients indicated for outpatient MIS-TLIF may benefit more from earlier intervention following onset of symptoms. CI - Copyright (c) 2022 Elsevier Inc. All rights reserved. FAU - Nie, James W AU - Nie JW AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. FAU - Hartman, Timothy J AU - Hartman TJ AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. FAU - MacGregor, Keith R AU - MacGregor KR AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. FAU - Oyetayo, Omolabake O AU - Oyetayo OO AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. FAU - Zheng, Eileen AU - Zheng E AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. FAU - Singh, Kern AU - Singh K AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. Electronic address: kern.singh@rushortho.com. LA - eng PT - Journal Article DEP - 20220719 PL - United States TA - World Neurosurg JT - World neurosurgery JID - 101528275 SB - IM MH - Back Pain/etiology/surgery MH - Humans MH - Lumbar Vertebrae/surgery MH - Minimally Invasive Surgical Procedures MH - *Spinal Fusion/adverse effects MH - Treatment Outcome OTO - NOTNLM OT - Ambulatory OT - Inpatient OT - MCID OT - MIS-TLIF OT - Outpatient OT - PROMs OT - Transforaminal Lumbar Interbody Fusion EDAT- 2022/07/22 06:00 MHDA- 2022/10/06 06:00 CRDT- 2022/07/21 19:37 PHST- 2022/06/16 00:00 [received] PHST- 2022/07/12 00:00 [revised] PHST- 2022/07/13 00:00 [accepted] PHST- 2022/07/22 06:00 [pubmed] PHST- 2022/10/06 06:00 [medline] PHST- 2022/07/21 19:37 [entrez] AID - S1878-8750(22)01004-X [pii] AID - 10.1016/j.wneu.2022.07.055 [doi] PST - ppublish SO - World Neurosurg. 2022 Oct;166:e599-e606. doi: 10.1016/j.wneu.2022.07.055. Epub 2022 Jul 19.