PMID- 35869740
OWN - NLM
STAT- MEDLINE
DCOM- 20220908
LR  - 20230916
IS  - 1752-2978 (Electronic)
IS  - 1752-296X (Linking)
VI  - 29
IP  - 5
DP  - 2022 Oct 1
TI  - Can low-carbohydrate diets be recommended for reducing cardiovascular risk?
PG  - 413-419
LID - 10.1097/MED.0000000000000750 [doi]
AB  - PURPOSE OF REVIEW: This review provides a rationale for implementing carbohydrate 
      restriction as a dietary therapy to improve biomarkers of cardiovascular health 
      and suggests that this will require a paradigm shift away from what is currently 
      promulgated as a 'heart-healthy' diet. RECENT FINDINGS: Type 2 diabetes mellitus 
      (T2DM), metabolic syndrome, and related co-morbidities are major risk factors for 
      cardiovascular disease (CVD). Ideally, then, a diet intended to support 
      cardiovascular health should be one that improves or reverses these underlying 
      risk factors. Carbohydrate restriction is effective for this purpose as well as 
      for favorably impacting atherogenic dyslipidemia. Recent consensus reports from 
      select national organizations have endorsed low-carbohydrate diets for improving 
      glycemia and cardiovascular risk. Reluctance among public health organizations 
      and some clinicians to more widely promote this therapeutic nutritional approach 
      is driven primarily by the increase in serum low-density lipoprotein cholesterol 
      (LDL-C) observed in a proportion of individuals who adopt a low-carbohydrate 
      diet. Here we explore the rationale for using carbohydrate restriction to improve 
      cardiovascular health by way of favorably impacting T2DM and insulin resistance, 
      and why this salutary effect outweighs the potential adverse effects of an 
      increase in serum LDL-C. SUMMARY: Carbohydrate restriction is a logical 
      foundation for a dietary intervention intended to reduce CVD risk, particularly 
      among individuals with T2DM or metabolic syndrome.
CI  - Copyright (c) 2022 The Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Berger, Amy
AU  - Berger A
AD  - Private Practice Nutritionist.
FAU - Thorn, Eric
AU  - Thorn E
AD  - Virginia Hospital Center Physician Group Cardiology, Arlington, Virginia, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220816
PL  - England
TA  - Curr Opin Endocrinol Diabetes Obes
JT  - Current opinion in endocrinology, diabetes, and obesity
JID - 101308636
RN  - 0 (Blood Glucose)
RN  - 0 (Cholesterol, LDL)
SB  - IM
MH  - Blood Glucose/metabolism
MH  - *Cardiovascular Diseases/etiology/prevention & control
MH  - Cholesterol, LDL
MH  - *Diabetes Mellitus, Type 2
MH  - Diet, Carbohydrate-Restricted
MH  - Heart Disease Risk Factors
MH  - Humans
MH  - *Metabolic Syndrome
MH  - Risk Factors
EDAT- 2022/07/24 06:00
MHDA- 2022/09/09 06:00
CRDT- 2022/07/23 03:42
PHST- 2022/07/24 06:00 [pubmed]
PHST- 2022/09/09 06:00 [medline]
PHST- 2022/07/23 03:42 [entrez]
AID - 01266029-202210000-00002 [pii]
AID - 10.1097/MED.0000000000000750 [doi]
PST - ppublish
SO  - Curr Opin Endocrinol Diabetes Obes. 2022 Oct 1;29(5):413-419. doi: 
      10.1097/MED.0000000000000750. Epub 2022 Aug 16.