PMID- 35870775
OWN - NLM
STAT- MEDLINE
DCOM- 20221216
LR  - 20221222
IS  - 1873-1597 (Electronic)
IS  - 1572-1000 (Linking)
VI  - 40
DP  - 2022 Dec
TI  - Prognostic factors associated with the course of vitreomacular traction in eyes 
      with age-related macular degeneration.
PG  - 103025
LID - S1572-1000(22)00311-8 [pii]
LID - 10.1016/j.pdpdt.2022.103025 [doi]
AB  - CLINICAL RELEVANCE: Vitreomacular traction(VMT) is a clinical syndrome that can 
      cause decreased vision and may affect the treatment response in cases of 
      age-related macular degeneration(AMD). Factors affecting the course of VMT in AMD 
      cases will guide the clinician in terms of patient management. BACKGROUND: The 
      aim of this study was to determine the prevalence of VMT in patients with AMD, to 
      evaluate the natural course of VMT, and to investigate factors associated with 
      the prognosis of VMT in eyes with AMD. METHODS: This retrospective case series 
      was conducted with 55 eyes of 46 patients who were diagnosed as having AMD 
      accompanying with VMT. Demographic data, complete ophthalmologic examination 
      findings, type of AMD, receiving an intravitreal injection(IVI), number of IVIs, 
      and the presence of complete spontaneous release were obtained from the medical 
      records of the patients. The horizontal length of VMT(HLVMT), central macular 
      thickness(CMT), the horizontal length of choroidal neovascularization(HLCNV) were 
      evaluated from spectral-domain optical coherence tomography(SD-OCT) images. 
      RESULTS: Spontaneous release was observed in 7(28%) eyes of the exudative AMD 
      group and 10(33.3%) eyes of the nonexudative AMD group. On the last visit, the 
      HLVMT was increased in 22(40%) of the eyes and a decrease in HLVMT was observed 
      in 8(14.5%) of the eyes. In the remaining 12(21.8%) eyes had unchanged HLVMT. In 
      all eyes with CNV, the area of VMT corresponded in 100% with localization of the 
      CNV complex. No significant difference was found between the eyes with 
      spontaneous release and persistent traction in terms of the type of AMD, IVI, 
      HLVMT, age, gender, and crystalline lens status. CONCLUSION: In this study, VMT 
      was observed at higher rates in eyes with exudative AMD compared to the eyes with 
      nonexudative AMD. However, spontaneous release rates were found close to those 
      with idiopathic VMT independently of the type of AMD, HLVMT, and IVI.
CI  - Copyright (c) 2022 Elsevier B.V. All rights reserved.
FAU - Garip, Ruveyde
AU  - Garip R
AD  - Department of Ophthalmology, Trakya University School of Medicine, Edirne, 
      Turkey. Electronic address: ruveydegarip@gmail.com.
FAU - Cinar, Ayca K
AU  - Cinar AK
AD  - Department of Ophthalmology, Trakya University School of Medicine, Edirne, 
      Turkey. Electronic address: aycakupeli@gmail.com.
FAU - Cinar, Abdulkadir C
AU  - Cinar AC
AD  - Department of Ophthalmology, Trakya University School of Medicine, Edirne, 
      Turkey.
FAU - Sakallioglu, Ahmet Kursad
AU  - Sakallioglu AK
AD  - Department of Ophthalmology, Trakya University School of Medicine, Edirne, 
      Turkey.
FAU - Guclu, Hande
AU  - Guclu H
AD  - Department of Ophthalmology, Trakya University School of Medicine, Edirne, 
      Turkey.
FAU - Gurlu, Vuslat
AU  - Gurlu V
AD  - Department of Ophthalmology, Trakya University School of Medicine, Edirne, 
      Turkey.
LA  - eng
PT  - Journal Article
DEP - 20220720
PL  - Netherlands
TA  - Photodiagnosis Photodyn Ther
JT  - Photodiagnosis and photodynamic therapy
JID - 101226123
SB  - IM
MH  - Humans
MH  - Vitreous Body/pathology
MH  - Retrospective Studies
MH  - Prognosis
MH  - Visual Acuity
MH  - Tissue Adhesions/pathology
MH  - *Photochemotherapy/methods
MH  - *Macular Degeneration/epidemiology
MH  - Tomography, Optical Coherence/methods
OTO - NOTNLM
OT  - Age related macular degeneration
OT  - Optical coherence tomography
OT  - Vitreomacular traction
COIS- Declaration of Competing Interest Authors declare no conflict of interest. The 
      manuscript has been read and approved by all the authors. The requirements for 
      authorship have been met, and each author believes that the manuscript represents 
      honest work.
EDAT- 2022/07/24 06:00
MHDA- 2022/12/15 06:00
CRDT- 2022/07/23 19:28
PHST- 2022/04/21 00:00 [received]
PHST- 2022/07/18 00:00 [revised]
PHST- 2022/07/19 00:00 [accepted]
PHST- 2022/07/24 06:00 [pubmed]
PHST- 2022/12/15 06:00 [medline]
PHST- 2022/07/23 19:28 [entrez]
AID - S1572-1000(22)00311-8 [pii]
AID - 10.1016/j.pdpdt.2022.103025 [doi]
PST - ppublish
SO  - Photodiagnosis Photodyn Ther. 2022 Dec;40:103025. doi: 
      10.1016/j.pdpdt.2022.103025. Epub 2022 Jul 20.