PMID- 35873122 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220726 IS - 1011-6842 (Print) IS - 1011-6842 (Linking) VI - 38 IP - 4 DP - 2022 Jul TI - Effects of Addition of Inspiratory Muscle Training to Exercise-Based Cardiac Rehabilitation on Inspiratory Muscle Strength, Peak Oxygen Consumption, and Selected Hemodynamics in Chronic Heart Failure. PG - 485-494 LID - 10.6515/ACS.202207_38(4).20220117A [doi] AB - BACKGROUND: Evidence supports the clinical benefits of isolated inspiratory muscle training (IMT) in patients with chronic heart failure (CHF); however, the rationale of IMT in combination with exercise training in cardiac rehabilitation settings for CHF has yet to be confirmed. OBJECTIVE: This study aimed to assess the effect of the addition of IMT in combination with aerobic/resistance training (AT/RT) on maximal inspiratory pressure (PImax), peak oxygen consumption (VO(2peak)), selected hemodynamic variables, and health-related quality of life (HRQoL) compared to sham-IMT combined with AT/RT in patients with CHF. METHODS: Twenty-five male patients with CHF completed a 6-month cardiac rehabilitation program of either a sham-IMT/AT/RT program (control group, 51.84 +/- 4.56 years old, n(1) = 13), or a real-IMT/AT/RT program (study group, 51.75 +/- 4.73 years old, n(2) = 12). Inclusion criteria were ischemic heart failure, New York Heart Association (NYHA) class II-III, and reduced ejection fraction. Outcome measures were PImax, VO(2peak), resting heart rate (RHR), heart rate (HR) reserve, rate pressure product (RPP), left-ventricular ejection fraction, and Minnesota Living with Heart Failure Questionnaire (MLwHFQ). Absolute mean changes from baseline (Delta) in the outcome measures were statistically analyzed as independent outcomes. RESULTS: DeltaPImax, DeltaRHR, DeltaHR reserve, and DeltaMLwHFQ total score were significantly greater in the study group than in the control group (p < 0.05). In addition, DeltaRPP showed an observed difference in favor of the study group with a tendency towards statistical significance (p = 0.07). CONCLUSIONS: IMT could be a successful complementary intervention to exercise-based cardiac rehabilitation programs comprising AT/RT, yielding greater improvements in PImax, RHR, HR reserve, and HRQoL in male patients with ischemic heart failure (NYHA class II-III). FAU - Ahmad, Ahmad Mahdi AU - Ahmad AM AD - Department of Physical Therapy for Cardiovascular and Respiratory Disorders, Faculty of Physical Therapy, Cairo University. FAU - Hassan, Mai Helmy AU - Hassan MH AD - Department of Physiotherapy, National Heart Institute, Giza, Egypt. LA - eng PT - Journal Article PL - China (Republic : 1949- ) TA - Acta Cardiol Sin JT - Acta Cardiologica Sinica JID - 101687085 PMC - PMC9295030 OTO - NOTNLM OT - Cardiac rehabilitation OT - Chronic heart failure OT - Exercise OT - Inspiratory muscle training OT - Quality of life EDAT- 2022/07/26 06:00 MHDA- 2022/07/26 06:01 PMCR- 2022/07/01 CRDT- 2022/07/25 03:31 PHST- 2021/09/12 00:00 [received] PHST- 2022/01/17 00:00 [accepted] PHST- 2022/07/25 03:31 [entrez] PHST- 2022/07/26 06:00 [pubmed] PHST- 2022/07/26 06:01 [medline] PHST- 2022/07/01 00:00 [pmc-release] AID - 10.6515/ACS.202207_38(4).20220117A [doi] PST - ppublish SO - Acta Cardiol Sin. 2022 Jul;38(4):485-494. doi: 10.6515/ACS.202207_38(4).20220117A.